Combiflam Tablet

Combiflam Tablet treats inflammations as well as pain. This medicine is a combination of two non-steroidal anti-inflammatory drugs (NSAIDs), viz. Ibuprofen and Paracetamol. NSAIDs control hormones that cause pain and inflammation in the body.

It thus offers relief from several problems like toothache, headache, arthritis, pain in the back, other types of small injuries and menstrual cramps. This medication is suitable for adults as well as children who are 6 months and above.

Ensure that you do not take Combiflam Tab if:

• You have heart disease and are at a risk of suffering from a stroke or heart attack.
• You have recently had a bypass operation.
• You are allergic to any substance that is present in Combiflam Tablet.

If you have health problems like asthma, fluid retention, kidney issues, frequent development of ulcers and bleeding, ask you medical practitioner if you can take Combiflam Tablet.

Combiflam medicine should not be taken during the last trimester of pregnancy as it has been found that it can harm the fetus. Research has not revealed if the drug is harmful to infants who are still breastfeeding. In this case, it is best that you take your doctor’s advice.

Get in touch with your health care provider as soon as possible if you develop some of these serious side effects like pain in the stomach, indigestion, problems with breathing, weight gain, itchy skin, feeling excessively tired and weak, problems with urination and bowel movements, development of acid in the stomach etc.

If self-administered, use exactly as directed (do not increase dose or frequency); adverse reactions can occur with overuse. Do not take longer than 3 days for fever, or 10 days for pain without consulting a medical advisor.

Management of a nonsteroidal anti-inflammatory drug (NSAID) intoxication is primarily supportive and symptomatic. Fluid therapy is commonly effective in managing the hypotension that may occur following an acute NSAID overdose, except when this is due to acute blood loss.

Seizures tend to be very short-lived and often do not require drug treatment; although, recurrent seizures should be treated with I.V. diazepam. Since many of the NSAIDs undergo enterohepatic cycling, multiple doses of charcoal may be needed to reduce the potential for delayed toxicities.

• Dysmenorrhea

• Fever And Pain

• Headache

• Pain In Muscles

• Joint Pain

• Allergy

• Asthma

• Kidney Disease

• Severe Liver Impairment

• Coronary Artery Bypass Surgery (Cabg)

• Peptic Ulcer

• Acid Or Sour Stomach

• Abdominal Discomfort

• Constipation

• Heartburn

• Indigestion

• Nausea

• How long is the duration of effect?

  The duration of effect lasts for 6-8 hours.

• What is the onset of action?

  The onset of action occurs anytime between 30 minutes to one hour after taking it.

• Are there any pregnancy warnings?

  No, this medicine is not safe for pregnant women as it can affect the foetus.

• Is it habit forming?

  There are no habit forming tendencies reported with this pill.

• Are there any breast-feeding warnings?

  No, this medicine is not safe for breastfeeding women as it can affect the baby.

• Is It safe with alcohol?

  This medicine is not safe with alcohol.

• Is it safe to drive while on this medicine?

  Yes, you can drive after taking this pill.

• Does this affect kidney function?

  Patients who have impaired kidney function should not take this pill as it can lead to more kidney problems.

• Does this affect liver function?

  Patients who have impaired liver function should not take this pill as it can lead to more liver problems, including liver failure.

Below is the list of medicines, which have the same composition, strength and form as Combiflam Tablet , and hence can be used as its substitute.

• Brufamol Tablet

  Menarini India Pvt Ltd

• Zupar 400 mg/325 mg Captab

  Glaxo SmithKline Pharmaceuticals Ltd

• Ibunij 400 Mg/325 Mg Tablet

  Sunij Pharma Pvt Ltd

• Lupiflam 400 mg/325 mg Tablet

  Lupin Ltd

• Ibupar 400 mg/325 mg Tablet

  Troikaa Pharmaceuticals Ltd

• Ibudex 400 mg/325 mg Tablet

  Wockhardt Ltd

• Pyremol Plus Ib 400 Mg/325 Mg Tablet

  Alembic Pharmaceuticals Ltd

• Lupiflam M Tablet

  Lupin Ltd

• Bruceta Forte 400mg/325mg Tablet

  Alkem Laboratories Ltd

• Arfen Compound 400 mg/325 mg Tablet

  Centaur Pharmaceuticals Pvt Ltd

• Are there any missed dose instructions?

  If you miss a dose, you should take one as soon as you remember that you’ve missed the dose.

• Are there any overdose instructions?

  If you have overdosed on the pill, you must consult your doctor immediately. Certain signs of overdose include confusion, drowsiness and lightheadedness.

It is a nonsteroidal anti-inflammatory drug that works by inhibiting the enzymes cyclo-oxygenase I and II. This leads to a decrease in the synthesis of prostaglandins that regulate fever, inflammation, pain and swelling.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  When taken with alcohol, this pill can increase the patients risk of developing liver problems.

• Interaction with Lab Test

  5-HIAA Urine Test

  You may get a false-positive result for this test if you take Combiflam Tablet.

• Interaction with Medicine

  • One must take caution while taking this medicine. This medication may interact with other medications like Ketoconazole, Metformin, Anti-hypertensives, Methotrexate, Corticosteroids, Aspirin if administered concomitantly.
  • Increased toxicity: May increase digoxin, methotrexate, and lithium serum concentrations; other nonsteroidal anti-inflammatories may increase adverse gastrointestinal effects.

• Interaction with Disease

  It can have negative interactions with certain diseases. These include kidney problems, fluid retention, pregnancy, ulcers, bleeding, and asthma..

• Interaction with Food

  Food may decrease the rate but not the extent of oral absorption; drug may cause GI upset, bleeding, ulceration, perforation; take with food or milk to minimize GI upset

• Ques : What is Combiflam Tablet?

  Ans : It is a combination of paracetamol and ibuprofen and is used to diminish linked to menstrual cycles and arthritis. It is used to relieve the pain related to everyday aches like headache, toothache, muscle pain or back pain etc. The ibuprofen present in the Combiflam decreases the hormones that cause pain and inflammation in the body. Whereas, paracetamol on the other hand blocks chemical that causes pain and it lowers the fever by changing the temp of the body according to the brain.

• Ques : What Combiflam Tablet used for?

  Ans : It is a widely popular medicine and is used almost in every case such as fever and pain, Mellow pain, Menstrual Cramps, Osteoarthritis, Rheumatoid Arthritis and Appetite. Also in problems like Asthma, Fluid Retention, Kidney Issues, frequent Development of ulcers and bleeding you can take combiflam if your doctor suggests it. Women in the 3rd trimester of their pregnancy shall not consume this medicine.

• Ques : What are the side effects of Combiflam Tablet?

  Ans : The side effects of Combiflam Tablet include Nausea or Vomiting, Rash, Gastric or Mouth Ulcer, Abnormal Blood Counts, Fatigue, Heartburn, Abdominal Discomfort, Constipation, Loss of appetite, Drowsiness, etc If any of these symptoms occur, you should consult your doctor and if it gets worse you should contact the emergency services. Combiflam is consumed by a large mass of population and these side effects are found in a very small number of the population.

• Ques : Can we take Combiflam Tablet empty stomach?

  Ans : Painkillers can aggravate the stomach lining because they have components like ibuprofen, aspirin and other NSAIDs. Painkillers such as Paracetamol do not aggravate the stomach and therefore they can be eaten empty stomach. Whereas the medicines like aspirin shall be taken with some food or fruits or with a glass of milk.

• Ques : Is Combiflam Tablet good for health?

  Ans : Consuming limited dosage of medicine is good for health. Overdose of this medication can cause various health issues such as respiratory disorders, asthma and other lung problems.

• Ques : Does Combiflam Tablet have paracetamol?

  Ans : Yes, it is a medication that contains paracetamol as an active ingredient present in it.

• Ques : Is Combiflam Tablet anti inflammatory?

  Ans : Yes, It is a medication that comes under non steroidal anti-inflammatory drugs.

• Ques : Can Combiflam Tablet be taken for toothache?

  Ans : Combiflam Tablet is a painkiller medication. It can be used to give relief in pain during toothache, but it can not treat toothache.

• Combiflam: Uses, Side Effects, Mechanism,Dosage- Drugs Bank [Internet]. drugsbanks.com. 2018 [Cited 24 April 2019]. Available from:

  https://www.drugsbanks.com/combiflam/

• Acetaminophen mixture with ibuprofen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/ibuprofen%20%252F%20acetaminophen

• Ibuprofen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/ibuprofen

• Acetaminophen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/paracetamol