Combither At 120 MG Injection

Combither At 120 MG Injection very effective in the treatment of severe malaria caused by Plasmodium falciparum strains when other medicines fail to show positive results. However, it cannot be used to prevent malaria.

The active constituent of this medicine is a derivative of artemisinin is a water-soluble hemisuccinate. It can be given by injection into a vein or a muscle or taken by mouth.

This medicine is generally well-tolerated in the body. It appears to be safe to use during pregnancy or breastfeeding. If you have faced a previous severe allergic reaction to this drug then you should avoid the use of it.

This medicine should be avoided as it includes isoniazid, amiodarone, methoxsalen, desipramine, ketoconazole, letrozole, methoxsalen, and tranylcypromine.

The recommended dose for adults and children over 6 months is generally 5 mg and should be taken orally on the first day. The dose gradually increases and is used in combination with other medicines to cure malaria. If the administration of this medication is happening in the form of injections then that should be performed by a healthcare professional.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Malaria

  This medicine is used to treat malaria caused by Plasmodium falciparum strain of the parasite. It may also be used for the treatment of malaria that are resistant to other medicines.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Allergy

  This medicine is not recommended for use if you have a known history of allergy to Combither At 120 MG Injection.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Dizziness

• Headache

• Abdominal Pain

• Diarrhoea

• Injection Site Pain

• Fever With Body Pain

• Anemia

• Low Wbc Count

• Swelling Of The Liver

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• How long is the duration of effect?

  The time duration for which the effect of this medicine persists is not established.

• What is the onset of action?

  The time taken for this medicine to show its effect is not established. However, it reaches the peak level in the body within an hour of administration.

• Are there any pregnancy warnings?

  Use of this medicine in pregnant women is not recommended unless absolutely necessary.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  Use of this medicine while breastfeeding is not recommended unless necessary.

• Does this affect kidney function?

  Caution must be taken. Dose adjustment is needed in case of patients with impaired renal function.

• Does this affect liver function?

  Caution must be taken. Dose adjustment is needed in case of patients with impaired liver function.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Below is the list of medicines, which have the same composition, strength and form as Combither At 120 MG Injection , and hence can be used as its substitute.

• Falcigo 120 MG Injection

  Zydus Cadila

• Falcinil Forte 120 MG Injection

  Zuventus Healthcare Ltd

• Larinate 120 MG Injection

  Ipca Laboratories Pvt Ltd.

• Match Ar 120 MG Injection

  Mankind Pharmaceuticals Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Missed Dose instructions

  Contact your doctor immediately if you miss a scheduled dose of this medicine.

• Are there any overdose instructions?

  Contact your doctor immediately if an overdose with this medicine is suspected.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• India

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

This medication acts on the schizonts (ring stage) in the blood and causes the lysis of the parasite.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Medicine

  Mefloquine

  Report the use of mefloquine or any other anti-malarial medicine to the doctor before receiving Combither At 120 MG Injection. You may require a dose adjustment and more frequent monitoring when using these medicines together.

  Pyrimethamine

  Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent monitoring while using these medicines together.

• Interaction with Disease

  Liver Disease

  This medicine should be administered with caution in patients having an impaired liver function. Appropriate diagnostic tests must be performed before determining the dose regimen. Suitable dose adjustment and frequent monitoring may be needed to ensure safe and effective use.

  Kidney Disease

  This medicine should be administered with caution in patients having an impaired kidney function. Suitable dose adjustment and frequent monitoring may be needed to ensure safe and effective use.

• Interaction with Food

  Food

  Information not available.

• Ques : What is Combither At 120 MG Injection?

  Ans : This medication a derivative of artemisinin is a water-soluble hemisuccinate. It is very effective in the treatment of severe malaria caused by Plasmodium falciparum strains when other medicines fail to show positive results.

• Ques : How long do I need to use Combither At 120 MG Injection before I see improvement in my condition?

  Ans : This medication is to be taken till the time you see an improvement in your health conditions.

• Ques : At what frequency do I need to use Combither At 120 MG Injection?

  Ans : The recommended dose for adults and children over 6 months is generally 5 mg per kg orally on the first day. In a few areas, a higher dose of 25 mg may be required for a cure to be obtained.

• Ques : Should I use Combither At 120 MG Injection empty stomach, before food or after food?

  Ans : This medication should be taken after food in a prescribed dosage.

• Ques : What are the instructions for the storage and disposal of Combither At 120 MG Injection?

  Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

• Artesunate- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 16 December 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/artesunate

• Artesunate- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 16 December 2019]. Available from:

  https://www.drugbank.ca/drugs/DB09274

• Artesunate- WHO Model Prescribing Information: Drugs Used in Parasitic Diseases - Second Edition [Internet]. apps.who.int 1995 [Cited 16 December 2019]. Available from:

  https://apps.who.int/medicinedocs/en/d/Jh2922e/2.5.11.html

• Lumefantrine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 16 December 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/lumefantrine