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Overview

Crocin 500 MG Tablet

Manufacturer :  Glaxosmithkline Pharmaceuticals Ltd
Medicine Composition :  Paracetamol
Prescription vs OTC : Prescription by Doctor not required

About Crocin 500 MG Tablet

Crocin 500 MG Tablet is used a pain-relieving medication. It is primarily used to treat acute pain. The conditions of acute pain include backache, headache, arthritis and toothache, etc.

The active ingredient falls under the class of analgesics, belonging to the category of NSAID. This medication also reduces pain in the body caused due to fever.

You should not consume this tablet if:

  • You are allergic to this medicine.
  • You are suffering from a serious liver disorder.
  • You normally consume more than 3 alcohol beverages per day or have a history of alcoholism.

You must not take the medicine in more than the amount prescribed or longer than the prescribed period. It can be taken with food or without it, but you must take it, in the same way, every day.

The medicine must be swallowed whole, without trying to crush, break or mixing it in water. As it is a pain reliever, it is unlikely that you will miss a dose. In case you do, refrain from taking two doses together to make up for the missed one.

In case of overdosing, Acetylcysteine 140 mg/kg orally (loading) followed by 70 mg/kg every 4 hours for 17 doses. Therapy should be initiated based upon laboratory analysis suggesting high probability of hepatotoxic potential. Activated charcoal is very effective at binding acetaminophen.

Take exactly as directed (do not increase dose or frequency); most adverse effects are related to excessive use. Take with food or milk. While using this medication, avoid alcohol and other prescription or OTC medications that contain acetaminophen.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). This medication will not reduce inflammation; consult prescriber for anti-inflammatory, if needed.

    What are the uses of Crocin 500 MG Tablet

    What are the contraindications of Crocin 500 MG Tablet ?

    What are the side effects of Crocin 500 MG Tablet ?

    Key highlights of Crocin 500 MG Tablet

    • How long is the duration of effect?

      The effect usually lasts upto 6 hours after intake.

    • What is the onset of action?

      The effect of the drug can be seen or felt within one hour after oral administration, the effect is noticed within 10 minutes if it is intravenously administered.

    • Are there any pregnancy warnings?

      It is not considered safe for expecting mothers to take this medication as there may be some danger to the fetus.

    • Is it habit forming?

      No, habit forming tendencies have not been reported.

    • Are there any breast-feeding warnings?

      It is safe for breast feeding mothers as the drug does not pass through breast milk.

    • Is It safe with alcohol?

      No, it is not safe to consume the drug with alcohol as there can be adverse side effects.

    • Is it safe to drive while on this medicine?

      This drug has been reported to cause dizziness and nausea, hence it is not safe or recommended to drive while taking this drug.

    • Does this affect kidney function?

      This does not cause affect kidney functions, if the kidney is already weak due to pre-medications then it is advised not to take this medication.Dosing interval in renal impairment:

      • Clcr 10-50 mL/minute: Administer every 6 hours.
      • Clcr <10 mL/minute: Administer every 8 hours (metabolites accumulate).
      • Hemodialysis: Moderately dialyzable (20% to 50%).

    • Does this affect liver function?

      Appears to be well tolerated in cirrhosis; serum levels may need monitoring with long-term use. Kindly consult your doctor before taking Crocin 500 MG Tablet.

    What are the substitutes for Crocin 500 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Crocin 500 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The drug is to be taken as and when required, however, one should not consume more than 4 grams of the drug per day as there are chances of over dosing.

    • Are there any overdose instructions?

      In case of an overdose contact the nearest emergency room or consult the doctor immediately. Overdoes may cause liver damage if immediate action is not taken.

    How does this medication work?

    Crocin 500 MG Tablet works by inhibiting the synthesis of prostaglandins in the central nervous system and peripherally blocks pain impulse generation; produces antipyresis from inhibition of hypothalamic heat-regulating center.

      What are the interactions of Crocin 500 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Excessive intake of alcohol may increase the risk of acetaminophen-induced hepatotoxicity; avoid or limit alcohol intake.
      • Interaction with Medicine

        Increased toxicity: Barbiturates, carbamazepine, hydantoins, sulfinpyrazone can increase the hepatotoxic potential of acetaminophen; chronic ethanol abuse increases risk for acetaminophen toxicity; effect of warfarin may be enhanced.
      • Interaction with Disease

        May cause severe hepatic toxicity on overdose; use with caution in patients with alcoholic liver disease; chronic daily dosing in adults of 5-8 g of acetaminophen over several weeks or 3-4 g/day of acetaminophen for 1 year have resulted in liver damage.
      • Interaction with Food

        May slightly delay absorption of extended-release preparations; rate of absorption may be decreased when given with food high in carbohydrates.

      FAQs about Crocin 500 MG Tablet

      • Ques : What is Crocin 500 MG Tablet?

        Ans : This is a medication that performs its action by obstructing the release of pain and fever chemical messengers.

      • Ques : What is the use of Crocin 500 MG Tablet?

        Ans : This medicine is used for the treatment and prevention of conditions and symptoms of diseases like Post immunization pyrexia, menstrual cramps and fever.

      • Ques : What are the side effects of Crocin 500 MG Tablet?

        Ans : Crocin 500 MG Tablet is a medication which has some commonly reported side effects. These side effects may or may not occur always and some of them are rare but severe. This is not a complete list and if you experience any of the below-mentioned side effects, contact your doctor immediately. Here are some side effects of Crocin 500 includes: Allergic reaction, gastric ulcers, fatigue, anaemia, nausea and vomiting are possible side effects.

      • Ques : Is Crocin 500 MG Tablet an antibiotic?

        Ans : No, Crocin 500 MG Tablet is not an antibiotic. It is classified as a mild analgesic used for the treatment of fever and is the most used painkiller. It is used to relieve mild to moderate pain in cases of back pain, headaches, arthritis, and toothaches. This Tablet decreases pain in the body caused due to fever. It is often given to patients with cancer or who are undergoing surgery to help them cope with pain. It is a prescribed medication which should only be used on a prescription.

      • Ques : How long do I need to use Crocin 500 MG Tablet before I see improvement in my condition?

        Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 to 3 days, before noticing an improvement in the condition. But the same duration is not mandatory for everyone and so, it is not a standard time period for this medication's action. Please consult your doctor, for the time period you need to consume this medication.

      • Ques : At what frequency do I need to use Crocin 500 MG Tablet?

        Ans : This medication is generally used once or twice a day, as the time interval to which this medication has an impact, is around 12 to 24 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

      • Ques : Should I use Crocin 500 MG Tablet empty stomach, before food or after food?

        Ans : This medication is advised to be consumed orally. The salts involved in this medication react properly if it is taken after having food. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

      • Ques : What are the instructions for the storage and disposal of Crocin 500 MG Tablet?

        Ans : This medication contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children. It is advised to dispose of the expired or unused medication, for avoiding its inadequate effect.

      • Ques : Is there any food or drink I need to avoid?

        Ans : You can follow your normal diet under the usage of this medication.

      • Ques : Will Crocin 500 MG Tablet be more effective if taken in more than the recommended dose?

        Ans : There is no need to take this medication more than its recommended doses.

      • Ques : Can I take other medications along with Crocin 500 MG Tablet?

        Ans : Do not use any OTC for cough, cold, allergy, or pain medication without consulting your doctor or pharmacist. Crocin 500 MG Tablet contains many combinations of medicines. If you use certain products together you may accidentally use too much of Paracetamol.

      • Ques : Can I take Crocin 500 MG Tablet with antibiotics?

        Ans : There are hundreds of antibiotics used to treat infections, so once you receive your prescription, ask your doctor or pharmacist if you can also take this medication at the same time that you take the antibiotic.

      • Ques : Is Crocin 500 MG Tablet an NSAID drug?

        Ans : No, this medication is not classified as an NSAID (Nonsteroidal anti-inflammatory drug). It is classified as a miscellaneous analgesic for mild to moderate pain and fever.

      References

      • Crocin: Uses, Side Effects, Precautions, Dosage- Drugs Bank [Internet]. drugsbanks.com. 2018 [Cited 24 April 2019]. Available from:

        https://www.drugsbanks.com/crocin/

      • Acetaminophen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/paracetamol

      • 7 Select Acetaminophen- acetaminophen tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2017 [Cited 23 April 2019]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=168da31e-de62-4280-9c66-2b41d2d93c31

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Rohini DhillonMBA( CHA), MBBS, PGDMCHGeneral Physician
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