Dasatinib

Dasatinib is primarily used to treat Philadelphia chromosome positive myeloid leukemia or lymphoblastic leukemia. It may also be used to treat Philadelphia chromosome positive myeloid or lymphoid blast phase when it is a chronic condition, or appears to be accelerating in growth. This drug is available in the form of tablets, and is meant to be administered orally. The recommended dosage for adults is 140 mg, taken once in a day. The tablets should not be crushed or chewed; they are meant to be swallowed, and can be taken either in the morning or in the evening, with or without meals.

Do not take this medicine if you are allergic to any of its components. This drug could potentially cause myelosuppression, cardiovascular disorders, bleeding problems, severe skin disorders, fluid retention and resultant swelling or edema, pulmonary arterial hypertension, fetal toxicity, and QT prolongation. This medicine could also cause a sudden and significant fall in the count of white blood cells, red blood cells, or platelets, so you will be advised to assess your blood cell counts once every week for the first two months, and then once a month after that.

There are no records of contraindications to this medication.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Chronic Myeloid Leukaemia

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Nausea

• Vomiting

• Abdominal Pain

• Rash

• Headache

• Edema (Swelling)

• Reduced Blood Platelets

• Musculoskeletal Bone

• Muscle Or Joint Pain

• Breathing Difficulty

• Anemia

• Fatigue

• Infections

• Fever

• Bleeding

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  Sprycel 50mg tablet is unsafe to use during pregnancy.
  There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.

• Are there any breast-feeding warnings?

  Sprycel 50mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.

• Is it safe to drive while on this medicine?

  Caution is advised when driving or operating machinery.

• Does this affect kidney function?

  There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Are there any missed dose instructions?

  If you miss a dose of Dasatinib, skip it and continue with your normal schedule. Do not double the dose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

Below is the list of medicines, which contains Dasatinib as ingredient

• Sprycel 50Mg Tablet

  Bms India Pvt Ltd

• Sprycel 70Mg Tablet

  Bms India Pvt Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

Dasatinib works as an inhibitor of the SRC-family tyrosine kinase and BCR-ABL kinase. As a result, it binds to these kinases and blocks their growth-promoting functions thus helps inhibit the growth of chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL).

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Dasatinib-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/dasatinib

• Dasatinib-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 2 June 2022].Available from:

  https://go.drugbank.com/drugs/DB01254

• DASATINIB Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=DASATINIB