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Overview

Derinide 400mcg Rotacap

Manufacturer :  Zydus Cadila
Medicine Composition :  Budesonide
Prescription vs OTC : Prescription by Doctor required

About Derinide 400mcg Rotacap

Derinide 400mcg Rotacap is a medication of the corticosteroid type that reduces inflammation in the body. It is available as a nasal spray, inhaler, pill and rectal form. For long-term management of asthma and chronic obstructive pulmonary disease, the inhaler is used.

The nasal spray is used for nasal polyps and allergic rhinitis. The pill in a delayed release form and rectal form treat various inflammatory bowel diseases including ulcerative colitis, Crohn’s disease and microscopic colitis.

There are a few side effects to taking this medicine as an inhaler which may include respiratory infections, cough, and headaches. Common side effects with the pills include vomiting, feeling tired and joint pains. Serious side effects include an increased risk of infection, cataracts and loss of bone strength.

Long-term use of the pill form may result in adrenal insufficiency. Stopping the use of the tablet suddenly after long-term use may therefore be dangerous. It is advised to use the inhaler form during pregnancy as it is considered to be a safer option.

Derinide 400mcg Rotacap is not prescribed to anyone younger than 18 years old, anyone having allergy, or anyone who is breastfeeding. If you are pregnant or plan to become pregnant, make sure you inform your doctor before taking this medicine.

Also inform your doctor if you have or have had tuberculosis, a serious bacterial, viral, or fungal infection, a weak immune system, high blood pressure, cataracts, cirrhosis or other liver disease, stomach ulcer, low bone mineral density, eczema, a personal or family history of diabetes or glaucoma.

Dosage is different for different people depending on their medical condition, the intensity of the medical condition, the age of the patient and so on. Do not intake more amounts of Derinide 400mcg Rotacap than prescribed. Rinse your mouth after the inhalation to prevent mouth infections. Consult the doctor if you experience any serious side effects or if you suspect an overdose.

Symptoms of overdose include irritation and burning of the nasal mucosa, sneezing, intranasal and pharyngeal Candida infections, nasal ulceration, epistaxis, rhinorrhea, nasal stuffiness, headache.

When consumed in excessive quantities, systemic hypercorticism and adrenal suppression may occur, in those cases discontinuation and withdrawal of the corticosteroid should be done judiciously.

Use as directed; do not increase dosage or discontinue abruptly without consulting prescriber. It may take several days for you to realize full effects of treatment. If you are also using an inhaled bronchodilator, wait 10 minutes before using this steroid aerosol.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the uses of Derinide 400mcg Rotacap

    • Asthma

      Derinide 400mcg Rotacap is used in the treatment of asthma which is an inflammation of airways characterized by breathing difficulty.

    • Crohn's Disease

      Derinide 400mcg Rotacap is used in the treatment of chron's disease which is an inflammation of the lining of the digestive system.

    • Ulcerative Colitis

      Derinide 400mcg Rotacap is used in the treatment of ulcerative colitis which is an inflammation of the lining of the large intestine.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the contraindications of Derinide 400mcg Rotacap ?

    • Allergy

      Not recommended in patients with known allergy to Derinide 400mcg Rotacap.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the side effects of Derinide 400mcg Rotacap ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    Key highlights of Derinide 400mcg Rotacap

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 6 to 11 hours.

    • What is the onset of action?

      The peak effect can be observed in 5 to 10 hours after an oral dose and 30 minutes after an inhaler.

    • Are there any pregnancy warnings?

      The inhaler is recommended in the pregnant women. The oral form of this medicine is not recommended for pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

    • Is it habit forming?

      No habit forming tendency has been reported

    • Are there any breast-feeding warnings?

      The oral form of this medicine is known to excrete through the breastmilk. Therefore, not recommended in breastfeeding women unless necessary. The amount of inhaled medicine is excreted in negligible amounts in breastmilk. Therefore, can be used in breastfeeding women.

    • Is It safe with alcohol?

      The effect of consuming alcohol while taking Derinide 400mcg Rotacap is not known. Kindly consult your doctor before taking it.

    • Is it safe to drive while on this medicine?

      No interaction was established or found.

    • Does this affect kidney function?

      No interaction was established or found.

    • Does this affect liver function?

      No interaction was established or found.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the substitutes for Derinide 400mcg Rotacap ?

    Below is the list of medicines, which have the same composition, strength and form as Derinide 400mcg Rotacap , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      If you miss a dose of Derinide 400mcg Rotacap, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    Where is the Derinide 400mcg Rotacap approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    How does this medication work?

    This medicine inhibits the cells and mediators release of various types including eosinophils, eicosanoids, mast cells, histamine, neutrophils, leukotrienes, macrophages, lymphocytes, and cytokines. These cells and mediators are responsible for inflammation caused. Thus the medicine aids in treating allergic disorders as well as reduces inflammation.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

      What are the interactions of Derinide 400mcg Rotacap ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Information not available.
      • Interaction with Medicine

        Clarithromycin

        These medicines are not recommended together due to increase in the concentration of Derinide 400mcg Rotacap. Inform the doctor if you have any symptoms like swelling, weight gain, high blood pressure, high blood glucose, and muscle weakness. An alternate medicine should be considered based on the clinical condition.

        Ketoconazole

        These medicines are not recommended together due to increase in the concentration of Derinide 400mcg Rotacap. Inform the doctor if you have any symptoms like swelling, weight gain, high blood pressure, high blood glucose, and muscle weakness. An alternate medicine should be considered based on the clinical condition.

        Antihypertensives

        Use with caution as this combination will decrease the effect of antihypertensives. This interaction is more likely to occur if this medicine is taken for more than a week. Inform the doctor if you are taking either of the medicines. Dose adjustments are to be made based on the clinical condition.

        Nonsteroidal anti-inflammatory drugs

        Use with caution as this combination will increase the risk of gastrointestinal bleeding. Inform the doctor if you are taking either of the medicines. Consider taking alternative medicine after consulting your doctor.
      • Interaction with Food

        Information not available.
      • Interaction with Disease

        • Controlled clinical studies have shown that inhaled and intranasal corticosteroids may cause a reduction in growth velocity in pediatric patients. Growth velocity provides a means of comparing the rate of growth among children of the same age.
        • FDA's Pulmonary and Allergy Drugs and Metabolic and Endocrine Drugs advisory committees discussed this issue at a July 1998 meeting. They recommended that the agency develop class-wide labeling to inform healthcare providers so they would understand this potential side effect and monitor growth routinely in pediatric patients who are treated with inhaled corticosteroids, intranasal corticosteroids or both.
        • Long-term effects of this reduction in growth velocity on final adult height are unknown. Likewise, it also has not yet been determined whether patients' growth will "catch up" if treatment in discontinued. Drug manufacturers will continue to monitor these drugs to learn more about long-term effects. Children are prescribed inhaled corticosteroids to treat asthma. Intranasal corticosteroids are generally used to prevent and treat allergy-related nasal symptoms.
        • Patients are advised not to stop using their inhaled or intranasal corticosteroids without first speaking to their healthcare providers about the benefits of these drugs compared to their risks.

      FAQs about Derinide 400mcg Rotacap

      • Ques : What is the common name for Derinide 400mcg Rotacap?

        Ans : There is no other name for Derinide 400mcg Rotacap.

      • Ques : What are the uses of the Derinide 400mcg Rotacap?

        Ans : Derinide 400mcg Rotacap is prescribed for the treatment of asthma and Irritable bowel syndrome.

      • Ques : How long do I need to use Derinide 400mcg Rotacap before I see improvement in my condition?

        Ans : Derinide 400mcg Rotacap needs to be taken as per the doctor’s recommendation.

      • Ques : At what frequency do I need to use Derinide 400mcg Rotacap?

        Ans : The frequency of the medication will be decided by your medical expert but it is advisable to take it at the same time until prescribed.

      • Ques : Should I use Derinide 400mcg Rotacap empty stomach, before food or after food?

        Ans : Derinide 400mcg Rotacap should be administered without food. Keep at least 1-2 distances between consumables and medication.

      • Ques : What are the instructions for the storage and disposal of Derinide 400mcg Rotacap?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      • Ques : Is Derinide 400mcg Rotacap safe after the consumption of alcohol?

        Ans : The effects of Derinide 400mcg Rotacap under the influence of alcohol are unknown. It is advisable not to overlap both of them.

      • Ques : Does Derinide 400mcg Rotacap develop an addiction?

        Ans : No, there are no signs of addiction in the patients.

      • Ques : Is Derinide 400mcg Rotacap safe during pregnancy?

        Ans : The oral form of Derinide 400mcg Rotacap is not prescribed during pregnancy, yet its inhaler form is safe to use.

      • Ques : Can one consume Derinide 400mcg Rotacap during the lactation period?

        Ans : No, the oral form of Derinide 400mcg Rotacap is not advisable as it can alter the milk and cause side effects in your newborn. Although its inhaler form can be consumed but only if your doctor gives you a green signal.

      • Ques : Is Derinide 400mcg Rotacap an Over The Counter medication?

        Ans : Yes, Derinide 400mcg Rotacap is a generic drug.

      References

      • Budesonide-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/budesonide

      • Budesonide-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 2 June 2022].Available from:

        https://go.drugbank.com/drugs/DB01222

      • BUDESONIDE respules,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=BUDESONIDE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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