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Overview

Diamox 250mg Tablet

Manufacturer :  Pfizer Ltd
Medicine Composition :  Acetazolamide
Prescription vs OTC : Prescription by Doctor not required

About Diamox 250mg Tablet

Used in combination with other medicines, Diamox 250mg Tablet is used to treat various kinds of edema, epilepsy and glaucoma. It is a carbonic anhydrase inhibitor. It increases the amount of water absorbed and removed by the kidney, reduces the fluid pressure in the eyeball by decreasing its formation, and blocks nerve discharges that cause seizures.

It is also prescribed as a diuretic, adjunct treatment of refractory seizures and acute altitude sickness; centrencephalic epilepsies (sustained release not recommended for anticonvulsant).

If your blood has low levels of potassium and sodium, or if you have adrenal gland problems or if you have high levels of chloride or other electrolyte problems, then Diamox 250mg Tablet is not to be prescribed. Taking aspirin alongside may increase the chance of Diamox 250mg Tablet’s side effects.

Diamox 250mg Tablet is taken with or without food from the mouth. It is recommended that you drink plenty of water while taking this medicine. If a stomach upset occurs while taking it, take it with some food so as to reduce irritation.

Some of the common side effects of Diamox 250mg Tablet are changes in taste, drowsiness, blurred vision, frequent urination, vomiting and diarrhea. Consult a doctor immediately if you experience severe allergic reactions, blood in the urine, convulsions, fever, etc.

Symptoms of overdose include low blood sugar, tingling of lips and tongue, nausea, yawning, confusion, agitation, tachycardia, sweating, convulsions, stupor, and coma. Hypoglycemia should be managed with 50 mL I.V. dextrose 50% followed immediately with a continuous infusion of 10% dextrose in water (administer at a rate sufficient enough to approach a serum glucose level of 100 mg/dL).

The use of corticosteroids to treat hypoglycemia is controversial, however, the addition of 100 mg of hydrocortisone to the dextrose infusion may prove helpful. Take as directed; do not chew or crush long-acting capsule (contents may be sprinkled on soft food). You will need periodic ophthalmic examinations while taking this medication.

    What are the uses of Diamox 250mg Tablet

    • Glaucoma

    • Edema (Swelling)

    • Seizure Disorders

    What are the contraindications of Diamox 250mg Tablet ?

    What are the side effects of Diamox 250mg Tablet ?

    Key highlights of Diamox 250mg Tablet

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      The tablet may be unsafe to use during pregnancy.

    • Are there any breast-feeding warnings?

      This medicine is probably unsafe to use during breastfeeding. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      This medicine should be used under close supervision.

    • Does this affect kidney function?

      Diamox 250mg Tablet is contra-indicated in cases of marked kidney and liver disease.

    • Does this affect liver function?

      There is no interaction between liver impairment and consuming this drug. So dose alteration is not needed.

    • How long is the duration of effect?

      The duration of action of this medicine may vary from 18 - 24 hours.

    • What is the onset of action?

      The effect of this medicine is initiated within 2 hours after its ingestion.

    What are the substitutes for Diamox 250mg Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Diamox 250mg Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    How does this medication work?

    The hindrance of carbonic anhydrase within the central nervous system results in anticonvulsant activity of this tablet. This resultantly lowers the tension brought on by the presence of carbon dioxide in the lung alveoli.

      What are the interactions of Diamox 250mg Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Lab Test

        May cause false-positive results for urinary protein with Albustix®, Labstix®, Albutest®, Bumintest®.
      • Interaction with Medicine

        • Decreased effect: Increased lithium excretion and altered excretion of other drugs by alkalinization of urine (such as amphetamines, quinidine, procainamide, methenamine, phenobarbital, salicylates); primidone serum concentrations may be decreased.
        • Increased toxicity: Cyclosporine trough concentrations may be increased resulting in possible nephrotoxicity and neurotoxicity; salicylate use may result in carbonic anhydrase inhibitor accumulation and toxicity including CNS depression and metabolic acidosis; digitalis toxicity may occur if hypokalemia is untreated.
      • Interaction with Disease

        Disease

        Patients suffering from bone marrow depression, diabetes, gout and metabolic acidosis should exercise caution while taking this tablet.

        • Use in impaired hepatic function may result in coma; use with caution in patients with respiratory acidosis and diabetes mellitus; impairment of mental alertness and/or physical coordination may occur.
        • Drug may cause substantial increase in blood glucose in some diabetic patients; malaise and complaints of tiredness and myalgia are signs of excessive dosing and acidosis in the elderly.
      • Interaction with Food

        May be administered with food to decrease GI upset.

      FAQs about Diamox 250mg Tablet

      • Ques : What is Diamox 250mg Tablet?

        Ans : Diamox Tablet is a medication which has Acetazolamide as an active element present in it. This medicine performs its action by constricting carbonic anhydrase, resulting in the diuresis of abnormal fluid retention.

      • Ques : What is the use of Diamox 250mg tablet?

        Ans : Diamox is a medication, which is used for the treatment and prevention from conditions such as Edema, Acute mountain sickness, and Glaucoma.

      • Ques : What are the side effects of Diamox 250mg tablet?

        Ans : Some side effects of this Tablet are Diarrhea, Vomiting, Loss of appetite, Numbness, tingling in arms or legs, Increased thirst, Increased urination frequency, Fever and cough, Blood in urine, Yellowing of skin and eyes, Sore throat, Unusual bleeding or bruising, Ringing or buzzing in the ears, etc.

      • Ques : What are the instructions for storage and disposal of Diamox 250mg tablet ?

        Ans : The Tablet should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      • Ques : How long do I need to use diamox 250mg tablet before I see improvement in my condition?

        Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor.

      • Ques : At what frequency do I need to use diamox 250mg tablet?

        Ans : This medication is generally used once or twice a day, as the time interval to which this medication has an impact, is around 12 to 24 hours, but it is not the standard frequency, for using this medication.

      • Ques : Should I use diamox 250mg tablet empty stomach, before food or after food?

        Ans : The salts involved in this medication react properly if it is taken with the food. If you take it on an empty stomach, it might upset the stomach.

      References

      • Acetazolamide- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 08 May 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/acetazolamide

      • ACETAZOLAMIDE- acetazolamide tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2018 [Cited 08 May2019]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0700a910-79aa-4431-aecf-637fe14fcae8

      • Acetazolamide- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 08 May 2019]. Available from:

        https://www.drugbank.ca/drugs/DB00819

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Yuvraj Arora MongaMD-Pharmacology, MBBSSexology
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