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Overview

Dibucaine

Prescription vs OTC : Prescription by Doctor required

About Dibucaine

Dibucaine is a local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. Dibucaine topical (for the skin) is used to treat minor pain and itching caused by burns, insect bites, sunburn, or other skin irritations. Dibucaine topical is also used to relieve rectal pain and itching caused by hemorrhoids or other rectal irritations.

Dibucaine is a quinoline derivative and amino amide with anesthetic activity. Dibucaine reversibly binds to and inactivates sodium channels in the neuronal cell membrane. Inhibition of sodium channels prevents the depolarization of nerve cell membranes and inhibits subsequent propagation of impulses along the course of the nerve, thereby limiting the excitation of nerve endings. This results in loss of sensation.

Common side effects :

The effect of this medicine can be observed within 15-30 minutes of application. This medicine is not recommended for use in pregnant women unless necessary and the potential benefits outweigh the risks involved. Consult your doctor before using this medicine. This medicine is not recommended for use in breastfeeding women unless necessary.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Anesthesiologist before using this medicine.

    What are the side effects of Dibucaine ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Anesthesiologist before using this medicine.

    Key highlights of Dibucaine

    • Is It safe with alcohol?

      No interaction found

    • Are there any pregnancy warnings?

      Otogesic 1.1% ear drop may be unsafe to use during pregnancy.
      Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Unknown. Human and animal studies are not available. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      There is no data available. Please consult doctor before consuming the drug.

    • Does this affect kidney function?

      There is no data available. Please consult doctor before consuming the drug.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Anesthesiologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Dibucaine, please consult your doctor.\n

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Anesthesiologist before using this medicine.

    Medicines containing Dibucaine

    Below is the list of medicines, which contains Dibucaine as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Anesthesiologist before using this medicine.

    How does this medication work?

    This medicine acts as a local or regional anaesthetic which works by inhibiting sodium channels, reducing membrane permeability of neurons for sodium and blocking the initiation as well as conduction of nerve impulses. This inhibits membrane depolarization and blocks conduction locally.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Anesthesiologist before using this medicine.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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