Diltiazem
About Diltiazem
Diltiazem obstructs calcium function, to effectively relax heart muscles and blood vessels. The drug is prescribed to patients who suffer from high blood pressure issues or have angina. Patients with various disorders of the heart rhythm may also be prescribed Diltiazem. The medicine is taken orally and the dosage should be strictly taken according to the prescription. This is primarily because Diltiazem can cause certain side effects, which may aggravate if the dosage is not right. Some side effects of Diltiazem are-
- light headedness
- Problems with breathing
- nausea and weakness
- dark urine and stool
- pain in the stomach
- rashes
- sore throat and fever
Other side effects may also occur, in which case a doctor should be immediately considered.
The medicine is generally not prescribed to patients with severe heart problems, for instance an AV block or suffer from hypotension. It is also not recommended for patients who have had a heart attack very recently. Doctors should be informed about any kidney problems, liver disease or allergies to make sure that the drug is safe for consumption. It is also not recommended for pregnant women or mothers who are breast feeding, unless absolutely essential. It is available either in the form of a table or a capsule, the drug is meant to be taken orally. Stopping the medicine suddenly can lead to severe consequences. In case the drug needs to be stopped it should be done gradually. It is always best that patients on Diltiazem keep checking their blood pressure to ensure that it is at the desired level. Diltiazem should be stored at room temperature and kept away from heat as well as moisture. An over dose of the drug can be highly fatal. Emergency medical aid should be acquired in this case.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.
What are the uses of Diltiazem
Diltiazem is used in the treatment of hypertension which is an increase in the blood pressure caused by genetic and environmental factors.
Angina Pectoris Prophylaxis
Diltiazem is used in the treatment of angina pectoris which is a type of heart disease characterized by chest pain caused due to emotional stress and smoking.
Diltiazem is used in the treatment of atrial fibrillation which is a type of heart disease characterized by irregular and fast heart rate.
Supraventricular Tachycardia
Diltiazem is used in the treatment of supraventricular tachycardia which is a type of heart disease characterized by fast heartbeat.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.
What are the contraindications of Diltiazem ?
Avoid if you have a known allergy to Diltiazem or any medicine belongs to the class calcium channel blockers.
Hypotension
This medicine is not recommended in the patients with the systolic blood pressure less than 90 mm Hg.
This medicine is not recommended in the patients with known case of myocardial infarction.
This medicine is not recommended in the patients with sick sinus syndrome except in the presence of a functioning ventricular pacemaker.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.
What are the side effects of Diltiazem ?
Body Pain
Chest Discomfort
Headache
Swelling Of The Hands, Ankles, Feet Or Lower Legs
Acid Or Sour Stomach
Muscle Pain
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.
Key highlights of Diltiazem
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 9 to 12 hours for an immediate release tablet, 12 to 24 hours for an extended release tablet, 15 to 30 hours for an extended release capsule, 9 to 12 hours for a single intravenous dose, 12 to 15 hours for an infusion.
What is the onset of action?
The peak effect of this medicine can be observed in 2 to 4 hours for an immediate release tablet, 11 to 18 hours for an extended release tablet and 10 to 14 hours for an extended release capsule.
Are there any pregnancy warnings?
This medicine is not recommended for pregnant women. Use under the supervision of the doctor, only if clinical condition clearly requires the use of this medicine.
Is it habit forming?
No habit forming tendencies were reported.
Are there any breast-feeding warnings?
This medicine is not recommended for breastfeeding women. Use only if clearly needed under the doctor's supervision. Monitoring of blood pressure is necessary.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.
What are the dosage instructions?
Missed Dose instructions
The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.
Are there any overdose instructions?
Seek emergency medical treatment or contact the doctor in case of an overdose.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.
Where is the Diltiazem approved?
India
United States
Japan
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.
Medicines containing Diltiazem
Below is the list of medicines, which contains Diltiazem as ingredient
- Diltime 90 MG Tablet SR
Zydus Cadila
- Dilzem 2% Gel
Torrent Pharmaceuticals Ltd
- Dtm 30 MG Tablet SR
Biochem Pharmaceutical Inds
- Dilzem 60 MG Tablet
Torrent Pharmaceuticals Ltd
- Dtm 60 MG Tablet SR
Biochem Pharmaceutical Inds
- Channel 30 MG Tablet
Micro Labs Ltd
- Dtm 90 MG Tablet SR
Biochem Pharmaceutical Inds
- Angizem Cd 90 MG Capsule
Sun Pharma Laboratories Ltd
- Diltilong 90 MG Tablet SR
Mankind Pharmaceuticals Ltd
- Cremagel 2% Gel
Abbott India Ltd
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.
How does this medication work?
This medication belongs to the class non-dihydropyridine calcium-channel blocker. It works by inhibiting the influx of calcium into the myocardial cells and vascular smooth muscle cells and thus inhibit the contraction of muscles and dilate the coronary and smooth muscle arteries.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.
What are the interactions of Diltiazem ?
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
- test
Interaction with Alcohol
Alcohol
Consumption of alcohol should be avoided while taking this medicine, especially when you start taking the medicine or a change its dosage. Symptoms like headache, dizziness, change in pulse or heart rate should be reported to the doctor.Interaction with Lab Test
Lab
Information not available.Interaction with Medicine
Carbamazepine
Combined use of these medicines is not recommended due to changes in the levels of these medicines. Any symptoms of headache, dizziness, visual disturbances should be reported to the doctor. Dose adjustments are to be made based on the clinical condition or an alternate medicine should be considered.Itraconazole
Combined use of these medicines is not recommended due to changes in the levels of Diltiazem. Any symptoms of swelling of hands, feet, dizziness should be reported to the doctor. Avoid operating machinery and driving vehicle. Dose adjustments are to be made based on the clinical condition or an alternate medicine should be considered.Ethinyl Estradiol
The blood levels of oral contraceptives may increase if taken with Diltiazem. Dose adjustments are to be based on the clinical condition or an alternate medicine should be considered.Atorvastatin
These medicines should be used with caution due to increase in the levels of atorvastatin which may cause severe muscle injury. Frequent monitoring of kidney function tests is necessary. Any symptoms of muscle pain, tenderness, dark colored urine should be reported to the doctor. Dose adjustments or an alternate medicine should be considered based on the clinical condition.Interaction with Disease
Aortic Stenosis
Diltiazem is not recommended in the patients with aortic stenosis as it may worsen the myocardial oxygen balance.Interaction with Food
Food
Information not available.
References
Diltiazem-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 28 May 2022].Available from:
https://druginfo.nlm.nih.gov/drugportal/name/diltiazem
Diltiazem-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 28 May 2022].Available from:
https://go.drugbank.com/drugs/DB00343
DILTIAZEM Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 28 May 2022].Available from:
https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=DILTIAZEM
Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.
Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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