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Overview

Diprovate Plus 0.05% Cream

Manufacturer :  Ranbaxy Laboratories Ltd
Medicine Composition :  Betamethasone
Prescription vs OTC : Prescription by Doctor required

About Diprovate Plus 0.05% Cream

Diprovate Plus 0.05% Cream is primarily prescribed to treat various rheumatic disorders such as systemic lupus erythematous and rheumatoid arthritis. It is also used against various skin diseases including psoriasis and dermatitis, allergic conditions such as angioedema and asthma, certain blood disorders, certain eye and skin conditions. Diprovate Plus 0.05% Cream belonging to the glucocorticoid class of medication, acts as a steroid.

Multiple sclerosis, crohn's disease and leukaemia can also be treated with Diprovate Plus 0.05% Cream. It can be administered into the body orally, in the form of an injection or applied as a cream. Being a corticosteroid, it works by decreasing inflammation and modifying the body's immune response to various conditions.

You are advised to not take this medication if you have allergy, systemic fungal infection or an active untreated infection. Diprovate Plus 0.05% Cream can interact with a few other medicines so inform your doctor if you take amlodipine, mifepristone, warfarin, ethinyl, estradiol, insulin, ciprofloxacin, BCG vaccine.

Also inform your doctor if you suffer from tuberculosis, electrolytic imbalance, gastrointestinal perforations, infections, myocardial infarction, ocular herpes infection, scleroderma or threadworm infection. This medicine is not recommended to use during pregnancy or breastfeeding unless absolutely required, in which case breastfeeding should be discontinued.

Serious side effects may include an increased risk of infection, severe allergic reactions, muscle weakness, and psychosis. Using Diprovate Plus 0.05% Cream for a long time can cause adrenal insufficiency. Discontinuing the medication suddenly after a long-term use may be dangerous. The cream commonly results in skin irritation and increased hair growth.

Take Diprovate Plus 0.05% Cream as instructed by the doctor. Your dosage duration, timings, forms and other attributes can vary depending on the medical condition and hence following instructions are necessary to ensure this medicine is safe and effective to use.

Take oral medication with or after meals. Limit intake of caffeine or stimulants. Prescriber may recommend increased dietary vitamins, minerals, or iron. Diabetics should monitor glucose levels closely (antidiabetic medication may need to be adjusted). Inform prescriber if you are experiencing greater than normal levels of stress (medication may need adjustment).

Some forms of this medication may cause GI upset (oral medication may be taken with meals to reduce GI upset; small frequent meals and frequent mouth care may reduce GI upset). You may be more susceptible to infection (avoid crowds and persons with contagious or infective conditions).

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the uses of Diprovate Plus 0.05% Cream

    • Allergy And Inflammation

    • Joint Inflammation

    • Eye Inflammation

    • Skin Disorders

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the contraindications of Diprovate Plus 0.05% Cream ?

    • Allergy

    • Systemic Fungal Infection

    • Active Untreated Infection

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the side effects of Diprovate Plus 0.05% Cream ?

    • Blurred Vision

    • Increased Appetite

    • Indigestion

    • Anxiety And Nervousness

    • Skin Itch

    • Drying And Cracking Of Skin

    • Acne

    • Change In Skin Color

    • Persistent Infections

    • Irregular Menstrual Periods

    • Depression

    • Growth Retardation In Children

    • Hoarseness Of Voice

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Key highlights of Diprovate Plus 0.05% Cream

    • How long is the duration of effect?

      The time duration for which this medicine remains effective is subject to vary depending on the form and route of administration.

    • What is the onset of action?

      The effect of this medicine can be observed within a few minutes after oral administration as it is rapidly absorbed from the gastrointestinal tract. It is subject to vary depending on the route of administration.

    • Are there any pregnancy warnings?

      Use of this medicine during pregnancy is not recommended unless absolutely necessary and the benefits outweigh the risks. Consult your doctor before using this medicine.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      Use of this medicine while breastfeeding is not recommended. However, if it absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before using this medicine.

    • Is It safe with alcohol?

      Consult your doctor before consuming alcohol.

    • Is it safe to drive while on this medicine?

      It is safe to drive while you are taking this drug unless you experience side effects of blurred vision.

    • Does this affect kidney function?

      It must be used cautiously if the patient has a history of kidney disorders.

    • Does this affect liver function?

      It does not affect the liver adversely.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the substitutes for Diprovate Plus 0.05% Cream ?

    Below is the list of medicines, which have the same composition, strength and form as Diprovate Plus 0.05% Cream , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      Contact your doctor for instructions if you missed a scheduled dose of this medicine. A self-attempt to make up for the lost dose may result in adverse effects.

    • Are there any overdose instructions?

      Contact your doctor if an overdose with this medicine for is suspected especially when the prescribed dose is very high. Symptoms may include thinning of the skin, easy bruising and bleeding, body fat deposits etc.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Where is the Diprovate Plus 0.05% Cream approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    How does this medication work?

    Diprovate Plus 0.05% Cream is a potent glucocorticoid with minimal mineralocorticoid action. It decreases inflammation by inhibiting the migration of leukocytes and reduces the permeability of capillaries and inhibiting prostaglandins and other inflammatory mediators.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

      What are the interactions of Diprovate Plus 0.05% Cream ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Information not available.
      • Interaction with Medicine

        Amlodipine

        Report the use of either of the medicine to the doctor. Taking these medicines together may reduce the efficacy of Amlodipine. You may need a dose adjustment and more frequent monitoring of blood pressure levels while using them together.

        Mifepristone

        These medicines should not be used together. Combining them would significantly reduce the efficacy of betamethasone. Your doctor may determine the best course of treatment in such cases.

        Warfarin

        Report the use of either of the medicine to the doctor. You may need a dose adjustment of warfarin based on the result of clotting time test performed. Any incidence of unusual bleeding and bruising, chest pain, loss of vision, swelling of arms and feet should be reported to the doctor immediately.

        Ethinyl Estradiol

        Ethinyl estradiol can potentially reduce the efficacy of betamethasone. You may need a dose adjustment and special test to safely use these medicines together. Do no stop the use of any medicine without consulting your doctor.

        Insulin

        Report the use of either of the medicine to the doctor. You may need a dose adjustment of the diabetic medicine and more frequent monitoring of blood glucose levels while using them together.

        Ciprofloxacin

        Report the use of either of the medicine to the doctor. The risks of adverse effects are significantly high especially in the elderly. Your doctor may prescribe a suitable alternative. Any pain or swelling of the tendons in the ankle, shoulder, biceps etc should be reported immediately.

        BCG vaccine

        This medicine should not be used when you have taken a vaccine containing a live and attenuated strain of the bacteria or virus. Report any recent vaccine taken to the doctor so that suitable alternatives could be prescribed.
      • Interaction with Disease

        Tuberculosis

        This medicine should be used with caution in patients who have recently recovered from tuberculosis. The risks of a relapse are significantly high and hence close monitoring of signs and symptoms is necessary.

        Electrolyte Imbalance

        This medicine is known to cause imbalances in the levels of minerals like calcium, potassium, and sodium in the body. Hence it should be administered with caution in patients with a pre-existing electrolyte imbalance disorder.

        Gastrointestinal Perforations

        This medicine is known to cause perforations and bleeding in the gut especially when high doses are consumed. Hence this medicine should be administered with caution in patients having a pre-existing perforation disorder of the stomach or intestine.

        Infections

        This medicine can suppress the immune system especially if the dose is high. This may increase the chances of contracting an infection or reduce the capacity to fight an infection. Hence, this medicine or corticosteroids, in general, should not be used in patients with active infections.

        Myocardial Infarction

        This medicine should be used with extreme caution in patients who have recovered or are recovering from a recent heart attack.

        Ocular Herpes Infection

        This medicine should be used with caution if the patient is suffering from an eye infection caused by herpes simplex virus.

        Scleroderma

        This medicine should be used with caution in patients suffering from this disease where the skin and connective tissue beneath becomes hard and stiff.

        Threadworm Infection

        This medicine should be used with caution in patients suffering from an infection caused by threadworm (Strongyloides).
      • Interaction with Food

        Information not available.

      FAQs about Diprovate Plus 0.05% Cream

      • Ques : What is Diprovate Plus 0.05% Cream?

        Ans : This drug is a steroid that inhibits the formation of chemicals in the body that may lead to inflammation (redness and swelling) and allergies.

      • Ques : What are the uses of Diprovate Plus 0.05% Cream?

        Ans : Diprovate Plus 0.05% Cream is helpful in treating allergic conditions.

      • Ques : What are the side effects of Diprovate Plus 0.05% Cream?

        Ans : Thinning of skin, Increased risk of infection, Weight gain, Mood changes and Behavioural changes are some of the known side effects of this medication.

      • Ques : Is Diprovate Plus 0.05% Cream a steroid?

        Ans : Yes, the drug comes under the category of corticosteroids and can help with many conditions including allergic reaction.

      • Ques : Is Diprovate Plus 0.05% Cream safe to use?

        Ans : This medication is considered safe to use if used in dose and duration as prescribed by the healthcare professional. However, it is not safe to use Diprovate Plus 0.05% Cream if you have a known history of allergy to it.

      • Ques : Does Diprovate Plus 0.05% Cream cause hair loss?

        Ans : Diprovate Plus 0.05% Cream does not cause hair loss. Moreover, it can lead to an increase in hair growth on the body when this drug is used for longer duration. Consult your doctor if you encounter this side effect.

      • Ques : Can I take Diprovate Plus 0.05% Cream with ibuprofen?

        Ans : It is suggested to first inform your doctor before taking any other medications in combination with Diprovate Plus 0.05% Cream to avoid the risk of any adverse interactions. Ibuprofen is a non steroid and may cause certain problems when taken with a steroidal drug like Diprovate Plus 0.05% Cream.

      • Ques : Does Diprovate Plus 0.05% Cream cause weight gain?

        Ans : Yes, this medication may lead to problems of weight gain in some individuals. This is more prominent if the drug is consumed for a long term. Please consult your healthcare expert if you are facing this symptom.

      • Ques : Is Diprovate Plus 0.05% Cream a hydrocortisone?

        Ans : No, this medication is not a type of hydrocortisone. Hydrocortisone is another type of drug that also belongs to the category of corticosteroids.

      • Ques : Is Diprovate Plus 0.05% Cream over the counter?

        Ans : This medicine is not an over the counter (OTC) drug. It can be used only when it is prescribed by a doctor.

      References

      • Betamethasone-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/betamethasone

      • Betamethasone-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 2 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00443

      • BETAMETHASONE cream,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=BETAMETHASONE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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