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Overview

Domi Up Syrup

Manufacturer :  Lincoln Pharmaceuticals Ltd
Medicine Composition :  Ondansetron
Prescription vs OTC : Prescription by Doctor required

About Domi Up Syrup

Domi Up Syrup belongs to the antiemetics drug group which is used to treat nausea as well as vomiting, caused by surgery, chemotherapy and radiation. This medication blocks the chemical serotonin from releasing in your gut and your central nervous system. Domi Up Syrup is available in four different forms i.e. tablet, disintegrating (dissolving) tablet, solution and film. It can be taken orally. This medication also comes in an IV (intravenous) form that can be injected into your body. You can take it with food or without food.

If you are allergic to Domi Up Syrup and other medications that block serotonin, along with other allergies, you must visit a doctor. The doctor must also know about the medical history of yours that whether you had problems such as liver disease, irregular heartbeat and stomach or intestinal problems in the past. If you are undergoing treatment for depression or any psychiatric disorder, you must discuss it with your doctor.

The dosage of this medication will depend on your medical condition and how your body is responding to the therapy. In children, the dose depends on their weight and height. If the patient is undergoing chemotherapy, he must take Domi Up Syrup orally 30 minutes before the treatment starts. In case of radiation, take this medication 1-2 hours before the treatment. It is also advised to take this medication before one hour before surgery. Overdose of this medication can lead to severe constipation, faint spells or feeling light-headed.

    What are the uses of Domi Up Syrup

    What are the contraindications of Domi Up Syrup ?

    What are the side effects of Domi Up Syrup ?

    Key highlights of Domi Up Syrup

    • How long is the duration of effect?

      This syrup is excreted primarily in urine and the effect of this medicine lasts for a duration of 12 to 28 hours.

    • What is the onset of action?

      The peak effect of Domi Up Syrup can be observed within 30 minutes for Intravenous and 2 hours for the medication.

    • Are there any pregnancy warnings?

      Use of Domi Up Syrup is not recommended in pregnant women.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      It is advised that breastfeeding women must consult doctor before using this syrup.

    What are the substitutes for Domi Up Syrup ?

    Below is the list of medicines, which have the same composition, strength and form as Domi Up Syrup , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any overdose instructions?

      Contact the doctor in case of overdose.

    • Are there any missed dose instructions?

      If you miss a dose, skip it and continue with your normal schedule. Do not double the dose.

    How does this medication work?

    Domi Up Syrup works by blocking 5-HT3 receptors peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone.

      What are the interactions of Domi Up Syrup ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Medicine

        Apomorphine

        Use of Domi Up Syrup with Apomorphine is not recommended. Replacement of the drug should be considered under the doctor's supervision. Usage of other medicines should be reported to the doctor.

        Amiodarone

        Use of Domi Up Syrup with Amiodarone is not recommended as it may cause dizziness, lightheadedness, difficulty in breathing if these drugs are used together. Regular cardiac function tests are to be performed if the patient is having any heart disease. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Usage of other medicines should be reported to the doctor.

        Amitriptyline

        If these drugs are used together, the patient may experience confusion, hallucination, changes in blood pressure, fever or excessive sweating. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Usage of other medicines should be reported to the doctor.

        Carbamazepine

        Patient's nausea and vomiting may not subside if these drugs are taken together. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.

        Phenytoin

        Patient's nausea and vomiting may not subside if these drugs are taken together. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.

        Cyclophosphamide

        The desired effect of cyclophosphamide will not be obtained if these drugs are concurrently taken. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.
      • Interaction with Disease

        Qt Prolongation

        Details of any heart disease, family history of an arrhythmia or any other drugs that cause QT interval prolongation (eg: Antipsychotics, Arrhythmia drugs) should be reported to the doctor. Regular cardiac function tests are to be performed if the patient is having any heart disease.

        Liver Disease

        Details of any liver disease (jaundice, hepatitis) or other drugs that may affect the liver (eg: TB drugs, HIV drugs) should be reported to the doctor. Regular liver function tests are to be performed if the patient is having any liver disease.
      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Content Details
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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