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Overview

Dompan Tablet

Manufacturer :  Medley Pharmaceuticals
Medicine Composition :  Domperidone, Pantoprazole
Prescription vs OTC : Prescription by Doctor not required

About Dompan Tablet

Dompan Tablet is indicated for treating GERD (Gastro-esophageal reflux disease), which does not respond to Pantoprazole medications alone. It prevents the tendency of vomiting and nausea in people suffering from gastrointestinal problems.

Dompan is a combination of Domperidone and Pantoprazole. The active ingredients fall under the class of dopamine antagonist and PPI (Proton pump inhibitor), respectively.

It is also prescribed to the patients of peptic ulcer and who take certain medicines for Parkinson’s disease. The medicine tightens the muscles near the entrance of the stomach and relaxes the ones present at the exit.

The action of this medication helps to speed up the passing of the food that you intake - from your stomach to your intestine, reducing the feeling of nausea and sickness, also preventing vomiting.

Dompan medicine also works by blocking or reducing the stimulation in the ‘vomiting centre’ of your brain, which will eventually reduce the feeling of nausea and vomiting. The possible side effects of taking this medication can be headache, migraine, dryness of the mouth or breast pain.

You are advised not to take Dompan Tablet if you have the following conditions:

  • An allergy to Dompan Tablet or any other ingredient of this medicine
  • Bleeding problems or blockage in your stomach or in the intestine
  • Tumour in the pituitary gland
  • Cardiac disease
  • Incorrect levels of magnesium, potassium or calcium in the blood
  • Severe/moderate liver impairment
Also Read: Rekool D Capsule Uses and Side Effects

    What are the uses of Dompan Tablet

    • Gastroesophageal Reflux Disease

    • Peptic Ulcer

    What are the contraindications of Dompan Tablet ?

    • Allergy

    • Tumor Of Pituitary Gland

    • Heart Diseases

    What are the side effects of Dompan Tablet ?

    Key highlights of Dompan Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts upto 6 hours.

    • What is the onset of action?

      The peak effect of this medicine is observed only after say about 30 to 60 minutes of administration.

    • Are there any pregnancy warnings?

      Dompan Tab should not be taken by pregnant woman unless extremely necessary. All the risks and benefits of the medicine should be discussed with the doctor.

    • Is it habit forming?

      There are no habit forming tendencies reported with this pill.

    • Are there any breast-feeding warnings?

      Dompan Tab is not recommended for the breast feeding mothers unless absolutely necessary. All the risks and benefits of the medicine should be discussed with the doctor.

    • Is It safe with alcohol?

      Consult your doctor before consuming alcohol.

    • Is it safe to drive while on this medicine?

      Consuming this medicine might cause dizziness in some people and when facing such a side effect, driving should be avoided.

    • Does this affect kidney function?

      Patients who have impaired kidney function should not take this pill as it can lead to more kidney problems.

    • Does this affect liver function?

      Patients who have impaired liver function should not take this pill as it can lead to more liver problems, including liver failure.

    What are the substitutes for Dompan Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Dompan Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose, you should take one as soon as you remember that you’ve missed the dose.

    • Are there any overdose instructions?

      If you have overdosed on the pill, you must consult your doctor immediately. Certain signs of overdose include confusion, chest pains, blurred vision and rash.

    How does this medication work?

    Dompan Tablet attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It, in turn, facilitates gastric emptying and decreases small bowel transit time. Also, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

      What are the interactions of Dompan Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Lab Test

        The patients taking Dompan Tablet have been reported for false results, as it interacts with investigations of Neuroendocrine Tumors, Secretin Stimulation Test, Urine Tests for THC. Thus an alternative confirmatory test should be considered to verify the results.
      • Interaction with Medicine

        Concomitant use of Antiretrovirals, warfarin, methotrexate, digoxin, Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole, itraconazole), tacrolimus, antiarrhythmics, apomorphine, protease inhibitors, systemic azole antifungals, some macrolides (erythromycin, clarithromycin and telithromycin) is contraindicated.
      • Interaction with Disease

        There are certain diseases with which this medicine interacts with, namely Liver disease, Osteoporosis and Hypomagnesemia. The medicine should be avoided when the above conditions persist or dose adjustments should be made as per the clinical condition.

      FAQs about Dompan Tablet

      • Ques : What is Dompan Tablet?

        Ans : Dompan Tablet is a part of the dopamine antagonists and PPI group of drugs which prevents the tendency of vomiting and nausea in people suffering from gastrointestinal problems and Parkinson’s disease. It contains Domperidone and Pantoprazole Sodium Sesquihydrate as active ingredients. Dompan Tablet works by reducing the amount of acid produced in the stomach thus blocking the dopamine receptors. It is available in the form of a tablet and has to be taken orally.

      • Ques : What is Dompan Tablet used for?

        Ans : Dompan Tab is used for the treatment and prevention from conditions and symptoms of diseases such as treatment for intractable nausea and vomiting, gastric ulcer, gas, gastrin-secreting tumor and ulcer in the small intestine.

      • Ques : What are the side effects of Dompan Tablet?

        Ans : Side effects of Dompan Tablet include diarrhea, blurred vision, dizziness, and headache.

      • Ques : Are there any specific contraindications associated with the use of Dompan Tablet?

        Ans : Dompan is not recommended for use in people having a known history of allergy to its constituents, hypersensitivity, active heart disease like congestive heart failure and also patients having a tumor of the pituitary gland.

      • Ques : Can the use of Dompan Tablet cause dry mouth?

        Ans : Yes, using Dompan can cause dry mouth. It can also lead to headache, migraine, nausea and vomiting.

      • Ques : Can the use of Dompan Tablet cause diarrhea?

        Ans : Yes, using Dompan can cause diarrhea. It can also lead to headache, migraine, nausea and vomiting.

      • Ques : What are the instructions for storage and disposal of Dompan Tablet?

        Ans : Dompan Tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets. It is important to dispose unused medications and expired medications properly to avoid adverse effects.

      • Ques : Can I take Dompan Tablet empty stomach?

        Ans : Yes. dompan is advised to take empty stomach.

      References

      • Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/rn/57808-66-9

      • Pantoprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/pantoprazole

      • Pantoprazole 40 mg gastro-resistant tablets- EMC [Internet]. www.medicines.org.uk. 2019 [Cited 24 April 2019]. Available from:

        https://www.medicines.org.uk/emc/product/7090/smpc

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Yuvraj Arora MongaMD-Pharmacology, MBBSSexology
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