Domperidone

Domperidone is indicated for treating the symptoms caused by vestibular disorders. It is also prescribed in vertigo/motion sickness, nausea, dizziness, headache, vomiting, the sensation of fullness when there is a delay in gastric emptying.

The active ingredient domperidone fall under the class of dopamine antagonist. The medicine tightens the muscles near the entrance of the stomach and relaxes the ones present at the exit.

The action of this medication helps to speed up the passing of the food that you intake - from your stomach to your intestine, reducing the feeling of nausea and sickness, also preventing vomiting.

This medicine also works by blocking or reducing the stimulation in the ‘vomiting centre’ of your brain, which will eventually reduce the feeling of nausea and vomiting. The possible side effects of taking this medication can be nausea, dryness in mouth, indigestion, sleepiness or weight gain.

You are advised not to take Domperidone if you have the following conditions:

• An allergy to Domperidone or any other ingredient of this medicine
• Bleeding problems or blockage in your stomach or in the intestine
• Tumour in the pituitary gland
• Cardiac disease
• Incorrect levels of magnesium, potassium or calcium in the blood
• Severe/moderate liver impairment

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Vertigo And Vestibular Disorders

• Vertigo

• Motion Sickness

• Nausea

• Vomiting

• Indigestion

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Allergy

• Depression

• Porphyria

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Skin Rash

• Weakness

• Dry Mouth

• Insomnia

• Excessive Sweating

• Unusual Tiredness And Weakness

• Depressed Mood

• Muscle Stiffness

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• How long is the duration of effect?

  The effect of this medicine lasts up to 6 hours.

• What is the onset of action?

  The peak effect of this medicine can be observed within 30 to 60 minutes of administration.

• Are there any pregnancy warnings?

  This medicine is not recommended for use in pregnant women unless the potential benefits outweigh the risks involved. The effect of this medicine on the fetus is not clearly established and hence you are advised to consult a doctor before taking this medicine.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not recommended for use by breastfeeding mothers as there is a risk of side effects on the infant. You are advised to consult your doctors and consider the potential benefit and risks before consuming this medication.

• Is It safe with alcohol?

  This fact remain unknown, whether it is safe or not to consume this medicine along with alcohol. Please consult the doctor before taking it.

• Is it safe to drive while on this medicine?

  This medicine may affect the alertness of the patient taking this medicine. Do not drive if you feel side effects affecting your alertness.

• Does this affect kidney function?

  Caution must be taken in patients with kidney disease. Dose adjustment is needed. Consult your doctor before taking this.

• Does this affect liver function?

  Caution must be taken in patients with liver disease. Dose adjustment is needed. Consult your doctor before taking this.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Are there any missed dose instructions?

  Skip the missed dose and resume with the next scheduled dose at the right time. The dose should not get doubled in an attempt to make up for the missed dose.

• Are there any overdose instructions?

  Contact your doctor if an overdose is suspected. Symptoms of overdose may include drowsiness, agitation, and convulsions and may be more prevalent in infants and children. Immediate medical attention including gastric lavage may be required in severe cases.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• India

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

Below is the list of medicines, which contains Domperidone as ingredient

• Gastractiv 10 MG Tablet

  Janssen

• Domstal 10 MG Tablet

  Torrent Pharmaceuticals Ltd

• Dombax 10 MG Tablet

  Ranbaxy Laboratories Ltd

• Motidom Mps 10 MG Tablet

  Tas Med (India) Private Ltd.������

• Motinorm 10 MG Tablet DT

  Medley Pharmaceuticals

• Domidon 10 MG Tablet

  Vintech Remedies

• Sinadom Tablet

  Leeford Healthcare Ltd

• Antem 10 MG Tablet

  Alembic Ltd

• Topra D 10 Mg/20 Mg Tablet

  View Laboratories

• Pantocid D Capsule

  Sun Pharmaceutical Industries Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

This medication attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It, in turn, facilitates gastric emptying and decreases small bowel transit time. Also, it prevents the relay of repetitive messages from the nerves in the inner ear to the vomiting centre in the brain. Thus altogether alleviates the symptoms.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Lab

  The patients taking this medicine have been reported for false results, as it interacts with investigations of Neuroendocrine Tumors, Secretin Stimulation Test, Urine Tests for THC. Thus an alternative confirmatory test should be considered to verify the results.

  Skin sensitivity test

  Report the use of this medicine to the doctor before a skin sensitivity test. This medicine may interfere with the procedure and may give false negative results. Use of this medicine should stop at least 4 days before the test is conducted.

• Interaction with Medicine

  Concomitant use of Antiretrovirals, warfarin, methotrexate, digoxin, Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole, itraconazole), tacrolimus, antiarrhythmics, apomorphine, protease inhibitors, systemic azole antifungals, some macrolides (erythromycin, clarithromycin and telithromycin) is contraindicated.

• Interaction with Disease

  Kidney Disease

  Domperidone should be used with caution if you are suffering from impaired kidney function. Suitable dose adjustment and safety monitoring is advised, especially if the impairment is severe.

  Liver Disease

  Domperidone should be used with caution if you are suffering from impaired liver function. Suitable dose adjustment and safety monitoring is advised, especially if the impairment is mild to moderate. For severe impairment, use of this medicine is not recommended.

  Intestinal Disorders

  Domperidone should be used with extreme caution in people having serious intestinal problems like internal bleeding, an obstruction or perforation of the stomach and intestine. Use of an alternate medicine is advised in such cases.

  Parkinson's Disease

  This medicine should be used with caution in patients suffering from Parkinson's disease. It should be used only when the potential benefits outweigh the risks involved with use.

• Interaction with Food

  Information not available.

• Ques : What is Domperidone used for?

  Ans : This medication is used to prevent symptoms including vestibular disorders, vertigo/motion sickness, nausea, the sensation of fullness when there is a delay in gastric emptying.

• Ques : Is Domperidone safe during pregnancy?

  Ans : You are advised to consult the doctor before consuming this drug if you are a pregnant woman.

• Ques : What is the best time of day to take Domperidone?

  Ans : The best time to take this medication is to consume it empty stomach or before the first meal. But it is not adequate for the patients who have known allergies to Domperidone or other medication of the same group.

• Ques : Is Domperidone safe while breastfeeding?

  Ans : This medicine is not adequate for the use of breastfeeding unless it’s extremely necessary. Consult your doctor about all the risks and benefits before consuming this medication.

• Ques : How long do I need to use Domperidone before I see improvement in my condition?

  Ans : This medication is to be taken till the time you see an improvement in your health conditions.

• Ques : At what frequency do I need to use Domperidone?

  Ans : This medication should be taken in the dosage as prescribed by the doctor.

• Ques : What are the instructions for the storage and disposal of Domperidone?

  Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

• Ques : Is Domperidone an over the counter drug?

  Ans : This drug is not over the counter (OTC) medicine and it is not advisable to take it without a prescription.

• Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 23 Nov 2021]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/domperidone

• EQUIDONE- domperidone gel- Daily Med [Internet]. dailymed.nlm.nih.gov. 2018 [Cited 23 Nov 2021]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e55d075e-2fe2-4405-b57a-59b85067e0c0

• Domperidone 10mg Tablets- EMC [Internet]. www.medicines.org.uk. 2021 [Cited 23 Nov 2021]. Available from:

  https://www.medicines.org.uk/emc/product/556/smpc