Epalrestat

Epalrestat, is a derivative of carboxylic acid which is used for hyperglycemic related complications like neuropathy, retinopathy or nephropathy. This medicine reduces intracellular sorbitol accumulations significantly. There is an improvement in the morphological abnormalities of the nerves once a diabetic is treated with this medicine.

Epalrestat, cannot be used in case one is hypersensitive, which is a contraindication. This cannot be used in case you suffer from severe hepatic insufficiency. You need to consult a doctor before taking this medicine in case you are breast feeding or are pregnant.

Epalrestat, is taken orally, with the dosage depending on your medical condition and response to the treatment. This should not be missed or discontinued at your own will. The medicine has to be taken at fixed times so that the medicine is effective and sustains the body balance of the patient.

It causes dizziness, drowsiness, hyper tension and may cause severe headaches. Thus one should not take this medicine if one is driving or working on heavy machinery. The other side effects may be hepatic dysfunction, vomiting, gastric discomfort, eruptions, exacerbation of renal function, numbness, edema or diarrohea.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

• Diabetic Nerve Disease

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

• Nausea

• Vomiting

• Liver Function Abnormal

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is it safe to drive while on this medicine?

  There is no data available. Please consult doctor before consuming the drug.

• Does this affect kidney function?

  There is no data available. Please consult doctor before consuming the drug.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

• Are there any missed dose instructions?

  If you miss a dose of Epalrestat, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

Below is the list of medicines, which contains Epalrestat as ingredient

• Aldonil Od 150Mg Tablet Sr

  Zydus Cadila

• Mepal 150Mg/1500Mcg Tablet

  KMS Health Center Pvt Ltd

• Epalpex 150Mg Tablet Sr

  Shilpex Pharmysis

• Alrista Plus Tablet SR

  Macleods Pharmaceuticals Pvt Ltd

• Epineuron Sr Tablet

  Aristo Pharmaceuticals Pvt Ltd

• Alrista 150Mg Tablet Sr

  Macleods Pharmaceuticals Pvt Ltd

• Epalridase 50mg Tablet

  East West Pharma

• Epalpex-M Sr Tablet

  Shilpex Pharmysis

• EPO 150MG TABLET

  Frankfurt Pharma Pvt Ltd

• Eparel 50mg Tablet

  Micro Labs Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

The medication is a reversible inhibitor for aldose reductase, which slows down the functionality of the said enzyme.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

• Epalrestat-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 10 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/epalrestat

• Epalrestat-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 10 June 2022].Available from:

  https://go.drugbank.com/drugs/DB15293