Epirubicin

Epirubicin falls under a category of drugs called anthracycline which is used for chemotherapy. It may also be referred to by its trade name Ellence. Epirubicin is used mainly as an adjuvant drug in association with other kinds of medications for breast cancer treatment in women, especially after surgery has been carried out. It is an anti-cancer drug used in therapy. But be careful as Epirubicin is a vesicant. It needs to be injected into your veins by trained hands only; your doctor or nurse. Epirubicin is injected into your body through free-flowing (IV) solution.

If Epirubicin escapes from your vein during the process of injecting, it may cause tissue damage or blisters which can be visible by redness or swelling. If such a mishap occurs inform your doctor immediately. Certain precautions that you must ensure to take before starting Epirubicin treatment are:

• Inform your doctor of existing medications that you are taking.
• Do not take Epirubicin if you are already pregnant or are planning to be anytime soon as it may cause threat to the fetus.
• Avoid this treatment also while you are breastfeeding your baby.
• Do not try to conceive while under Epirubicin treatment. For both men and women, use contraceptives.
• People with a history of heart failure or other heart related problems and those with bone marrow suppression diseases are prohibited from using this drug.
• Exposure to sun may cause problems. Extra care is advised to avoid sun exposure as much as it is possible.

Side-effects associated with Epirubicin treatment maybe short –term or long-term effects which occur in about 10-29% of cases. These may include, darkening of the skin area where radiation has been applied, diarrhea, infection, etc. Seek help and supervision within 24 hours when you face symptoms like nausea, vomiting, prolonged diarrhea, bleeding, swelling and fast or irregular heart beat.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Adjuvant For Breast Cancer

  Epirubicin is used along with other medications in the treatment of breast cancer.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Allergy

  Not recommended in patients with known allergy to Epirubicin.

• Heart Diseases

  Not recommended in patients with heart failure, recent myocardial infarction or severe arrhythmias

• Previously treated with epirubicin

  Not recommended in patients previously treated with maximum cumulative doses of Epirubicin or any anthracyclines.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Low Wbc Count

• Fever With Chills

• Blood In Urine

• Red Spots On Skin

• Irregular Heart Beat

• Joint Pain

• Diarrhoea

• Hair Loss Or Thinning Of The Hair

• Irregular Menstrual Periods

• Change In Skin Color

• Decreased Appetite

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 3 to 4 days.

• What is the onset of action?

  The peak effect of this medicine can be observed immediately after intravenous injection.

• Are there any pregnancy warnings?

  This medicine is not recommended for pregnant women.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not recommended in breastfeeding women.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Missed Dose instructions

  It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

Below is the list of medicines, which contains Epirubicin as ingredient

• Ciprubicin 50 MG Infusion

  Cipla Ltd

• Farmorubicin 10 MG Injection

  Pfizer Ltd

• Erubin 10 MG Injection

  Rpg Life Sciences Ltd

• Epixtra 10 MG Injection

  Zydus Cadila

• Epithra 10 MG Injection

  Glenmark Pharmaceuticals Ltd

• Epitaz 10 MG Injection

  Intas Pharmaceuticals Ltd

• Epirubitec 10 MG Injection

  United Biotech (P) Ltd

• Epirubicin 10 MG Injection

  Dr. Reddys Laboratories Ltd

• Epineon 10 MG Injection

  Neon Laboratories Ltd

• Epiglan 10 MG Injection

  Gland Pharma Limited

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

This medication falls under the category of an antibiotic and anticancer agent. It works by forming a complex with DNA by intercalation between base pairs and inhibits inhibition of nucleic acid (DNA and RNA) and protein synthesis. This intercalation inhibits topoisomerase II activity and inhibits cell growth. It also interferes with DNA replication and transcription by inhibiting DNA helicase activity.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Alcohol

  Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Lab

  Information not available.

• Interaction with Medicine

  Clozapine

  These medicines may further lower the white blood cell count if received together. Any symptoms of fever, diarrhea, sore throat, chills should be informed to the doctor. Close monitoring of blood cell count is necessary. An alternate medicine should be considered based on the clinical condition.

  Ketoconazole

  These medications may increase the risk of liver injury if taken together. The liver function should be assessed before starting the treatment. Any symptoms of abdominal pain, dark colored urine, unusual bleeding should be reported to the doctor. Dose reduction or an alternate medicine should be considered based on the clinical condition.

  Atorvastatin

  These medications may increase the risk of liver injury if taken together. The liver function should be assessed before starting the treatment. Any symptoms of abdominal pain, dark colored urine, unusual bleeding should be reported to the doctor. Dose reduction or an alternate medicine should be considered based on the clinical condition.

  Live vaccines

  You may be at the risk of developing infections if these medicines are taken together. Inform the doctor if you had received either of these medicines. Your doctor may postpone therapy based on the condition.

• Interaction with Disease

  Disease

  Information not available.

• Interaction with Food

  Food

  Information not available.

• Epirubicin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 3 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/epirubicin

• Epirubicin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 3 June 2022].Available from:

  https://go.drugbank.com/drugs/DB00445

• EPIRUBICIN injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 3 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=EPIRUBICIN