Eprex 8000 IU Injection
About Eprex 8000 IU Injection
Eprex 8000 IU Injection is a man-made synthetic erythropoietin that helps in the production of red blood cells in the body. It is produced in a cell culture by use of recombinant DNA technology. It increases the count of red blood cells in the body and is therefore a cure for anemia with chronic kidney failure, anaemia caused by chemotherapy for cancer and anaemia in certain HIV patients caused by taking zidovudine. People with high risk of blood loss due to surgeries take this medicine to reduce their need for blood transfusion. Eprex 8000 IU Injection produces red blood cells by causing stimulation of the bone marrow.
Eprex 8000 IU Injection should not be taken if :- You are allergic to any of the ingredients in Eprex 8000 IU Injection.
- You have very high blood pressure.
- You have developed pure red cell aplasia after receiving the first dose of Eprex 8000 IU Injection or other erythropoietin medicines.
Eprex 8000 IU Injection has a few side effects but most people experience no or minor effects. Side effects may include cough, headache, joint or bone pain, mild muscle pain, muscle spasm, pain and redness in injection site, nausea, vomiting and weight loss. In case of sever effects, seeking medical attention immediately is advised.
Ensure your doctor is informed about your other medications. Inform him if you are pregnant or breastfeeding, if you are on hemodialysis, if you have had or are scheduled to have a surgery recently. Consumption of Eprex 8000 IU Injection should be exactly like prescribed by the doctor and the dosage should not increase more than what is recommended. Overdosing may cause severe side effects to occur.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.
What are the uses of Eprex 8000 IU Injection
Chronic Kidney Disease Associated Anemia
Eprex 8000 IU Injection is used to treat anemia in patients having chronic kidney diseases.
Chemotherapy Associated Anemia
Eprex 8000 IU Injection is used to treat anemia associated with the use of chemotherapy medicines to treat certain specific types of cancer.
Anemia Due To Use Of Medicines
Eprex 8000 IU Injection is used to treat anemia associated with the use of Zidovudine to treat HIV infection.
Anemia Associated With Surgery
Eprex 8000 IU Injection is also used before and after certain surgeries where chances of significant blood loss is high. It reduces the dependency on blood transfusion process.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.
What are the contraindications of Eprex 8000 IU Injection ?
This medicine is not recommended for use if you have a history of allergy to epoetin alfa or albumin or any other ingredient present in the dosage form.
Non-Chemotherapy Associated Anemia In Cancer Patients
This medicine is not recommended for use to treat anemia in cancer patients who are are not receiving any chemotherapy medication.
This medicine is not recommended for use in patients who have high blood pressure and are not taking any medicine to control it.
Pure Red Cell Aplasia
This medicine is not recommended for use if the patient has had a history of pure red cell aplasia after using this medicine or other medicines belonging to the Eryhtropoietin class of drugs.
Use of multi-dose vials
Use of multi-dose vials of this medicine is not recommended for children or pregnant women. The risk of severe adverse effects are increasingly high in such cases.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.
What are the side effects of Eprex 8000 IU Injection ?
Headache
Muscle Or Joint Pain
Swelling And Redness At The Injection Site
Stomach Discomfort And Pain
Severe Skin Allergy
Swelling Of Face, Lips, Eyelids, Tongue, Hands And Feet
Difficulty In Breathing
Upper Respiratory Tract Infection
Difficulty In Swallowing
Increased Blood Pressure
Pure Red Cell Aplasia
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.
Key highlights of Eprex 8000 IU Injection
How long is the duration of effect?
The time for which the effect of this medicine persists is subjected to variations depending on the intended use.
What is the onset of action?
The effect of this medicine can be observed after several days of administration.
Are there any pregnancy warnings?
Use of this medicine is not recommended for pregnant women unless absolutely necessary. All the potential benefits and risks should be considered before administering this medicine. Use of this medicine containing benzyl alcohol as an ingredient and use of multi-dose vial is not recommended for pregnant women.
Is it habit forming?
No habit forming tendencies were reported
Are there any breast-feeding warnings?
Use of this medicine is not recommended for women who are breastfeeding an infant unless absolutely necessary. The use of benzyl alcohol containing dosage forms or multi-dose vials are not recommended.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.
What are the dosage instructions?
Missed Dose instructions
Contact your doctor if you have missed a scheduled dose of this medicine and follow all the instructions given.
Are there any overdose instructions?
Contact your doctor immediately if an overdose is suspected.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.
Where is the Eprex 8000 IU Injection approved?
India
United States
Japan
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.
How does this medication work?
This medication is a synthetic form of erythropoietin. It stimulates the proliferation and maturation of components that form the red blood cells in the body.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.
What are the interactions of Eprex 8000 IU Injection ?
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
- test
Interaction with Alcohol
Alcohol
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.Interaction with Lab Test
Lab
Information not available.Interaction with Medicine
Ramipril
Report the use of Ramipril of any other medicine used for lowering high blood pressure to the doctor. You may require a dose adjustment and more frequent monitoring of blood pressure level while using these medicines together.Cyclosporine
Report the use of either of the medication to the doctor. You may require undergoing clinical safety monitoring before using these medicines together.Thalidomide
Report the use of thalidomide to the doctor before receiving epoetin alfa. The risk of clot formation and associated side effects are very high if these medicines are used together. Your doctor may prescribe an alternate medication or administer these medications after adjusting the dose and safety monitoring.Interaction with Disease
This medicine should be used with caution in patients with elevated blood pressure levels especially if it is uncontrolled. Your doctor will ensure that the blood pressure is under control before the use of epoetin alfa starts.Seizure Disorders
This medicine should be used with caution in patients suffering from seizure disorders as the risk of adverse effects are significantly high. You may require clinical monitoring at least in the early stages of treatment with epoetin alfa.Blood Clotting Disorder
This medicine should be used with extreme caution in patients with blood clotting disorders since the risks of severe adverse effects are very high. Any disease of the heart and blood vessels should be reported to the doctor before treatment with epoetin alfa is initiated.Hemodialysis
This medicine should be administered with caution in patients undergoing hemodialysis. Suitable dose adjustment and clinical monitoring is recommended while giving this medicine.Interaction with Food
Food
Information not available.
References
Epoetin Alfa-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:
https://druginfo.nlm.nih.gov/drugportal/name/epoetin%20alfa
Epoetin Alfa-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 1 June 2022].Available from:
https://go.drugbank.com/drugs/DB00016
EPOETIN ALFA injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:
https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=EPOETIN+ALFA
Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.
Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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