Erythromycin 250 MG Tablet

Erythromycin 250 MG Tablet, a macrolide antibiotic is useful for the treatment of a number of bacterial infections. This includes skin infections, respiratory tract infections, chlamydia infections, syphilis and pelvic inflammatory disease. It is also used in conjunction with neomycin for decontaminating the bowel.

Streptococcal infection in newborns can be prevented by taking this medicine during pregnancy. Erythromycin 250 MG Tablet may also be used to improve delayed stomach emptying. It can be given intravenously and orally. This medicine is not supposed to be given to a child without a doctor's advice. It is also used in the treatment of gastroparesis.

Erythromycin 250 MG Tablet also has a few side effects. Common side effects include diarrhoea, vomiting and abdominal cramps. More serious side effects may include liver problems, allergic reactions and prolonged QT. To make sure Erythromycin 250 MG Tablet is safe for you, tell your physician if you have the following:

• Kidney or liver disease;
• Myasthenia gravis;
• Electrolytic imbalance (such as low potassium or magnesium levels in your blood);
• A history of Long QT syndrome;
• Breastfeeding a baby or;
• Taking medicines for heart rhythm disorder.

Your doctor may have to change your treatment plan if you use drugs such as cisapride, pimozide, ergotamine or dihyfroergotamine as these drugs interfere with the proper functioning of Erythromycin 250 MG Tablet.

Erythromycin 250 MG Tablet usually is taken every 6 hours (four times a day), every 8 hours (three times a day), or every 12 hours (twice a day). Skipping doses should be avoided as it may increase your risk of further infection which is resistant to antibiotics.

• Bacterial Infections

• Diphtheria

• Pertussis

• Gonorrhea And Associated Infections

• Syphilis

• Nongonococcal Urethritis

• Gastroenteritis

• Bowel Sterilization

• Gastroparesis

• Hypersensitivity

• Severe Liver Impairment

• Abdominal Pain

• Pelvic Pain And Cramping

• Nausea

• Vomiting

• Oropharyngeal Candidiasis

• Cholestasis

• Fever

• Rash

• Diarrhoea

• Thrombophlebitis

• How long is the duration of effect?

  The effect of this medication lasts for an average duration of 4 to 6 hours.

• What is the onset of action?

  The peak effect of this medication can be observed within 3 hours of oral administration.

• Are there any pregnancy warnings?

  This medication should be avoided by pregnant women unless suggested by the doctor. The effect of this medicine on fetus is not clearly established and hence, doctor consultation is recommended before consumption.

• Is it habit forming?

  No habit forming tendency has been reported.

• Are there any breast-feeding warnings?

  This medication is safe to use during breastfeeding. Any incidence of rashes on skin or diarrhea in the infant should be reported. It is advised to consult a doctor before taking this medicine.

• Is It safe with alcohol?

  This medicine is found to be unsafe if consumed along with Erythromycin.

• Is it safe to drive while on this medicine?

  This medicine does not usually affects patients ability to drive or his consciousness.

• Does this affect kidney function?

  This medicine is found to be safe to use in patients with renal disease. Adjustment of dose is not required. Consult your doctor for further details.

• Does this affect liver function?

  Caution must be taken in patients with liver disease. Adjustment of dose is needed. Kindly consult your doctor before taking this medicine.

Below is the list of medicines, which have the same composition, strength and form as Erythromycin 250 MG Tablet , and hence can be used as its substitute.

• Erycin 250 MG Tablet

  Cipla Ltd

• Erythrokem 250 MG Tablet

  Alkem Laboratories Ltd

• Eltocin 250 MG Tablet

  Ipca Laboratories Pvt Ltd.

• Erythrotone 250 MG Tablet

  Abbott Healthcare Pvt. Ltd

• Biomycin 250 MG Tablet

  Biochem Pharmaceutical Inds

• Missed Dose instructions

  The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

This medication is a macrolide antimicrobial that works by passively diffusing through cell membranes and reversibly binding to the 50S subunit of the bacterial ribosome. It prevents protein synthesis in the bacterial cells which can either stop their growth or cause death.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  False-positive urinary catecholamines may result.

• Interaction with Medicine

  • Protease inhibitor like amprenavir and ritonavir may increase erythromycin's serum concentration.
  • Erythromycin 250 MG Tablet decreases clearance of carbamazepine, cyclosporine, and triazolam, alfentanil, bromocriptine, digoxin (~10% of patients), disopyramide, ergot alkaloids, methylprednisolone; may decrease clearance of protease inhibitors.
  • Erythromycin 250 MG Tablet may decrease theophylline clearance and increase theophylline's half-life by up to 60% (patients on high-dose theophylline and erythromycin or who have received erythromycin for >5 days may be at higher risk).
  • Decreases metabolism of terfenadine, cisapride, and astemizole resulting in an increase in Q-T interval and potential heart failure.
  • Inhibits felodipine (and other dihydropyridine calcium antagonist) metabolism in the liver resulting in a twofold increase in levels and consequent toxicity.
  • Death has been reported by the potentiation of pimozide's cardiotoxicity when given concurrently with erythromycin. Use contraindicated.
  • May potentiate the anticoagulant effect of warfarin and decrease the metabolism of vinblastine.
  • Concurrent use of erythromycin and lovastatin and simvastatin may result in significantly increased levels and rhabdomyolysis.

• Interaction with Disease

  • Impaired Liver Function: Erythromycin should be used with caution in the patients with a history of liver disease. Frequent monitoring of liver function tests is necessary. Dose adjustments are to be made based on the severity of liver injury.
  • Qt Prolongation: Inform your doctor if you have arrhythmia, any heart disease or drugs that prolong QT interval such as psychiatric drugs and anti-arrhythmic drugs.
  • Myasthenia Gravis: Erythromycin should be used with caution in the patients with the history of Myasthenia Gravis as it may aggravate the weakness in these patients. Dose adjustments or an alternate medicine should be prescribed based on the medical condition.

• Interaction with Food

  Take Erythromycin at least 30 minutes before or 2 hours after meals. Consumption of grapefruit juice is not recommended as it may increase the concentration of Erythromycin and can cause undesired effects.

• Ques : What is Erythromycin 250 MG Tablet?

  Ans : This medication has Erythromycin as an active ingredient present. It performs its action by obstructing the growth of bacterias in the bacterial cell wall.

• Ques : What are the uses of Erythromycin 250 MG Tablet?

  Ans : This medication is used for the treatment and prevention from conditions and symptoms of diseases like community-acquired pneumonia, soft tissue infections, otitis media, bronchitis, pertussis, and upper respiratory tract infections.

• Ques : What are the Side Effects of Erythromycin 250 MG Tablet?

  Ans : This is a list of possible side-effects which may occur due to the constituting ingredients of this medication. These include diarrhea, fever, confusion, black or dark-colored stools, joints pain, dizziness, painful urination, and anxiety.

• Ques : What are the instructions for storage and disposal Erythromycin 250 MG Tablet?

  Ans : This medication should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.