Estrogen

Estrogen is a female sex hormone responsible for the regulation and development of the female reproductive system. It is used in the treatment of postmenopausal osteoporosis, female hypogonadism, etc.

The use of this drug is associated with increased risk of blood clotting, cardiovascular disease, stroke, uterine cancer or breast cancer. Before using this medication you should notify your doctor if you have or are:

• Pregnant or plan on becoming pregnant
• Breastfeeding
• A condition or history of-
  • Liver disease
  • Blood clotting
  • Stroke
  • Heart attack
• Allergic to any medicines.

It can be taken orally, vaginally, topically, or via injection. It should be taken only as per the prescribed dosage is given by the doctor according to your conditions.

Symptoms of overdose include fluid retention, jaundice, thrombophlebitis.Toxicity is unlikely following single exposures of excessive doses, any treatment should be supportive and symptomatic.

This drug can only be given I.M. It is important to maintain schedule of drug days and drug-free days. Periodic gynecologic exam and breast exams are important.

Report significant swelling of extremities, sudden acute pain in legs or calves, chest, or abdomen; shortness of breath; severe headache or vomiting; weakness or numbness of arms or legs; or unusual vaginal bleeding.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• Post Menopausal Osteoporosis

• Female Hypogonadism

• Primary Ovarian Failure

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• Breast Cancer

• Vaginal Bleeding

• Thrombophlebitis

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• Peripheral Edema

• Enlargement Of Breasts

• Breast Tenderness

• Nausea

• Anorexia

• Bloating

• Headache

• Increased Libido

• Vomiting

• Diarrhoea

• Depression

• Dizziness

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  Inform prescriber if you are pregnant. Do not get pregnant during or for 1 month following therapy. Consult prescriber for instruction on appropriate barrier contraceptive measures. This drug may cause severe fetal defects.

• Are there any breast-feeding warnings?

  The drug is suggested to be ignored by breastfeeding mothers as there is a possibility of side-effects on infant. You should consult your doctor to evaluate the potential benefits and risks before taking the medicine.

• Is it safe to drive while on this medicine?

  There is no data available. Please consult doctor before consuming the drug.

• Does this affect kidney function?

  There is no data available. Please consult doctor before consuming the drug.

• Does this affect liver function?

  Dosing adjustment of Estrogen in hepatic impairment:

  • Mild to moderate liver impairment: Dosage reduction of estrogens is recommended.
  • Severe liver impairment: Not recommended.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

• Are there any missed dose instructions?

  If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

Below is the list of medicines, which contains Estrogen as ingredient

• Premarin 1.25Mg Tablet

  Pfizer Ltd

• Premarin 0.30mg Tablet

  Pfizer Ltd

• Espauz 0.625mg Tablet

  Glenmark Pharmaceuticals Ltd

• Premarin 0.625Mg Tablet

  Pfizer Ltd

• Conjugase Tablet

  Elder Pharmaceuticals Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

This medication primarily functions as a regulator of the transcription rate for certain genes present in the uterus. This medication plays an active role as the sex hormone in the female body.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Lab Test

  Intake of this medication kight lead to interaction with the following test:

  • Decreased antithrombin III
  • Decreased serum folate concentration
  • Increased prothrombin and factors VII, VIII, IX, X
  • Increased platelet aggregability
  • Increased thyroid binding globulin
  • Increased total thyroid hormone (T4)
  • Increased serum triglycerides/phospholipids

• Interaction with Medicine

  • Decreased effect: Rifampin decreases estrogen serum concentrations.
  • Increased toxicity:
    • Hydrocortisone increases corticosteroid toxic potential.
    • Anticoagulants: Increases potential for thromboembolic events with anticoagulants.
    • Carbamazepine, tricyclic antidepressants, and corticosteroids; increased thromboembolic potential with oral anticoagulants.

• Interaction with Disease

  Use with caution in patients with asthma, epilepsy, migraine, diabetes, cardiac or renal dysfunction; estrogens may cause premature closure of the epiphyses in young individuals; safety and efficacy in children have not been established; estrogens have been reported to increase the risk of endometrial carcinoma, do not use estrogens during pregnancy.

• Ques : What is Estrogen?

  Ans : This drug is a female sex hormone responsible for the regulation and development of the female reproductive system. It is used in the treatment of postmenopausal osteoporosis and female hypogonadism.

• Ques : How long do I need to use Estrogen before I see improvement in my condition?

  Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition.

• Ques : At what frequency do I need to use Estrogen?

  Ans : The duration of the effect for this medicine is dependent on the severity of the patient’s condition. It is advised to follow the proper prescription of the doctor, directed according to the patient's condition.

• Ques : Should I use Estrogen empty stomach, before food or after food?

  Ans : This medication is advised to be consumed orally. The salts involved in this medication react properly if it is taken after having food. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

• Ques : What are the instructions for the storage and disposal of Estrogen?

  Ans : This medication contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children.

• Estrogens- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 3 December 2021]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/sid/d004967000

• ESTROGEN- folliculinum, oophorinum liquid- Daily Med [Internet]. dailymed.nlm.nih.gov. 2018 [Cited 24 Nov 2021]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0c72f252-433f-4a8f-968e-6a511cddafc9

• ESTROGEN PHENOLIC- estradiol, liquid- EMC [Internet]. www.medicines.org.uk. 2021 [Cited 24 Nov 2021]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=716cd86c-af47-45a6-b710-fed421e78fb5