Febuxostat

Febuxostat is used for decreasing the symptoms of gouty arthritis. It belongs to the group of medications called xanthine oxidase inhibitors. The medicine works by decreasing the level of uric acid by blocking the xanthine oxidase enzyme.

This enzymeis responsible for helping the body to make uric acid from xanthine. When there are high levels of uric acid in the blood, it can lead to gout and the symptoms associated with it.

Inform your doctor if you are pregnant or breastfeeding mothers. The medicine can pass on to the baby through breast milk. Also, your doctor must be informed before being prescribed this medication, if you ever had a-

• Medical history of cancer
• Liver disease
• Heart disease
• Kidney disease
• Organ transplantation
• stroke

Dosage of the medication depends on your age, the condition for which you are being treated and it’s severity, your medical history, and reaction to the first dose. It is available in tablet form to be taken orally. You can have the medicine with or without food. Usually, it is taken once a day but follow your doctor’s instructions regarding the dosage.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

• Gouty Arthritis

• Increased Uric Acid Level In Blood

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

• Hypersensitivity

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

• Itching Or Rash

• Headache

• Diarrhoea

• Liver Damage

• Oedema

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 15 to 24 hours.

• What is the onset of action?

  The peak effect of this medicine can be observed in 1 to 1.5 hours.

• Are there any pregnancy warnings?

  This medicine is not recommended for use during pregnancy unless absolutely necessary.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  No clear data is available about the presence of this medicine in the human breast milk.

• Does this affect kidney function?

  Caution must be taken in patient with kidney disease. Adjustment of dose might be needed. Kindly consult your doctor before taking this medication.

• Does this affect liver function?

  Caution must be taken in patient with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking this medication.

• Is It safe with alcohol?

  Caution must be taken while consuming alcohol with this medication. Kindly consult your doctor for more details.

• Is it safe to drive while on this medicine?

  This medication may cause side effects that might affect the alertness of the patient. Thus driving should be avoided if any of the side effect occurs.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

• Missed Dose instructions

  Take the missed dose as soon as you remember. However, if it is almost time for the next scheduled dose then the missed dose should be skipped.

• Are there any overdose instructions?

  Contact a doctor immediately if an overdose is suspected. Symptoms of overdose may include a change in pulse rates, severe drowsiness, confusion, vomiting, hallucinations, convulsions, and fainting. Immediate medical intervention may be required if the overdose symptoms are severe.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

Below is the list of medicines, which contains Febuxostat as ingredient

• Zurig 80 MG Tablet

  Zydus Cadila

• Febuset 40 MG Tablet

  Meyer Organics Pvt. Ltd

• Foxstat 40 MG Tablet

  Franco Indian Pharmaceuticals Pvt Ltd

• Febustat 40 MG Tablet

  Abbott Healthcare Pvt. Ltd

• Febucip 40 MG Tablet

  Cipla Ltd

• Febuxor 80 MG Tablet

  Intas Pharmaceuticals Ltd

• Febutaz 40 MG Tablet

  Sun Pharma Laboratories Ltd

• Feboxa 40 MG Tablet

  Ranbaxy Laboratories Ltd

• Furic 40 MG Tablet

  Ar-Ex Laboratories Pvt . Ltd

• Febuget 40 MG Tablet

  Sun Pharma Laboratories Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

This medication belongs to the class xanthine oxidase inhibitor. It works by inhibiting the xanthine oxidase enzyme thus inhibits the conversion of hypoxanthine to xanthine to uric acid without affecting the enzymes involved in purine and pyrimidine synthesis.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Medicine

  Azathioprine

  This medication is known to increase the levels of azathioprine and can cause serious effects. Inform the doctor if you are receiving these medications. An alternate medicine should be considered based on the clinical condition.

  Theophylline

  This medication is known to increase the levels of theophylline and can cause serious effects. Inform the doctor if you are receiving these medications. Required dose adjustments or an alternate medicine should be considered based on the clinical condition.

• Interaction with Disease

  Secondary Hyperuricemia

  This medicine is not recommended in the patients with malignant disease, tumor lysis syndrome or Lesch-Nyhan syndrome where uric acid levels are highly elevated.

• Ques : What is Febuxostat?

  Ans : This medication is helpful in decreasing the symptoms of gouty arthritis.

• Ques : What is Febuxostat used for?

  Ans : It is used to treat symptoms like swelling, pain, soreness, redness and stiffness in certain joints of the body associated with gout or arthritis.

• Ques : How long do I need to use Febuxostat before I see improvement in my condition?

  Ans : This medication is to be taken till the time you see an improvement in your health conditions.

• Ques : At what frequency do I need to use Febuxostat?

  Ans : This medication should be taken in the dosage as prescribed by the doctor.

• Ques : Should I use Febuxostat empty stomach, before food or after food?

  Ans : You can have the medicine with food or without it. Usually, it is taken once a day but follow your doctor’s instructions regarding the dosage.

• Ques : What are the instructions for the storage and disposal of Febuxostat?

  Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

• Ques : What are the side effects of Febuxostat?

  Ans : This drug can cause quite a few side effects like diarrhea, headache, rash, nausea, heart problems, gout flares, liver problems, and severe skin and allergic reactions.

• Ques : How long should I take Febuxostat?

  Ans : It should be taken for duration which is prescribed by the doctor as duration usually varies from person to person and also depends on the medical condition.

• Ques : Is Febuxostat better than allopurinol?

  Ans : Research and trials on humans have revealed that Febuxostat is better than allopurinol for decreasing the uric acid levels.

• Ques : What is the best time to take Febuxostat?

  Ans : You must consult a doctor to know the timings, however, one must prefer taking it the same time everyday.

• Ques : Can Febuxostat cause kidney damage?

  Ans : Febuxostat can cause problems related to kidneys which may lead to conditions of blood in the urine, frequent urination and kidney stones. Consult a doctor if you are facing such symptoms.

• Ques : Can I stop taking Febuxostat on my own if I am fine and have no pain or swelling in joints?

  Ans : Do not stop taking this drug without consulting a doctor as the symptoms can occur if the course of treatment is not completed.

• Ques : What are the things which I need to know while taking Febuxostat?

  Ans : Febuxostat can cause some problems related to heart and related symptoms such as chest pain, shortness of breath or trouble breathing, dizziness, fainting or feeling light-headed, rapid or irregular heartbeat. Hence, consult a doctor if you encounter these symptoms.

• Ques : Can Febuxostat cause any liver problems?

  Ans : The use of this drug may also lead to liver problems, hence blood tests should be done regularly during the course of treatment.

• Febuxostat- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 16 December 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/febuxostat

• Febuxostat- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 16 December 2019]. Available from:

  https://www.drugbank.ca/drugs/DB04854

• ULORIC- febuxostat tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2019. [Cited 16 December 2019]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=54de10ef-fe5f-4930-b91d-6bbb04c664bd