Floxsafe 400 MG Tablet

Floxsafe 400 MG Tablet is primarily prescribed for the treatment of mild to moderate community-acquired pneumonia, acute bacterial exacerbation of chronic bronchitis, and acute bacterial sinusitis.

Floxsafe 400 MG Tablet is a drug that belongs to the cluster of quinolone antibiotics that is administered to remedy bacterial infections. However, this medicine will not work for viral infections such as flu and the common cold. This antibiotic works by preventing the growth and further infestation of bacteria.

Remember that using an antibiotic repetitively for trivial issues or for problems not caused by bacteria will lead the bacteria to become resistant to that antibiotic. Thus the antibiotic will lose its efficacy over a period of time. You must drink sufficient fluids unless of course advised otherwise.

The length of the treatment plan and dosage of Floxsafe 400 MG Tablet will depend upon the severity of the condition. It is advised to take this drug about 4 to 8 hours prior to the intake of other minerals/vitamins or products containing magnesium or aluminium such as antacids.

For best results, take this medicine at regular intervals every day. Finish the course of the antibiotic even if your condition gets better; this is because stopping the intake of an antibiotic prematurely will result in the relapse of the infection and the bacteria turning antibiotic-resistant over a period of time.

This medicine may cause some of the side effects include nausea, sore throat, dizziness, lightheadedness, diarrhea, headaches and difficulty in sleeping. Although rare, a severe intestinal condition ‘Clostridium Difficile Diarrhea could develop.

Let your doctor know without any delay should you experience persistent diarrhoea or notice the presence of blood or mucous in the stool. Take note that prolonged intake of this drug, beyond the prescribed time limit, may result in the formation of white patches in the mouth (oral thrush) or a new yeast infection that could manifest itself in the form of vaginal discharges.

Potential symptoms of overdose may include CNS excitation, seizures, QT prolongation, and arrhythmias (including torsade de pointes). Patients should be monitored by continuous EKG in the event of an overdose. Management is supportive and symptomatic. Not removed by dialysis.

May be taken with or without food. Drink plenty of fluids. Avoid direct exposure to direct sunlight during therapy and for several days following. Do not take antacids within 4 hours before or 8 hours after dosing.

Contact your physician immediately if signs of allergy occur. Contact your physician immediately if signs of tendon inflammation or pain occur. Do not discontinue therapy until your course has been completed. Take a missed dose as soon as possible, unless it is almost time for your next dose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Community Acquired Pneumonia

• Chronic Bronchitis

• Sinusitis

• Skin And Structure Infection

• Intra-Abdominal Infections

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Allergy

• Tendinitis Or Tendon Rupture

• Myasthenia Gravis

• Qt Prolongation

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Abdominal Pain

• Dizziness

• Headache

• Nausea

• Diarrhoea

• Vomiting

• Dyspepsia

• Altered Sense Of Taste

• Abnormal Liver Function Tests

• Chest Pain

• Arthralgia

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 12 hours.

• What is the onset of action?

  The peak effect of this medicine can be observed in 0.5 to 4 hours.

• Are there any pregnancy warnings?

  This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

• Is it habit forming?

  No habit forming tendency has been reported.

• Are there any breast-feeding warnings?

  Use of this medicine is not recommended for women who are breastfeeding due to the adverse effect on the development of the infant's joints. Use only if clearly needed under the supervision of the doctor. Monitoring of undesired effects like diarrhea, diaper rash is necessary.

• Is It safe with alcohol?

  Consumption of alcohol is found to be safe if taken along with this medication.

• Is it safe to drive while on this medicine?

  This medication can cause side effects that may affect the alertness of the patient. Thus driving should be avoided, if you are taking this medication.

• Does this affect kidney function?

  This medicine is found to be safe to use in patients with kidney disease. Adjustment of dose is not needed. Inform your doctor if you face any issue.

• Does this affect liver function?

  No dosage adjustment is required in mild hepatic insufficiency (Child-Pugh Class A). Not recommended in patients with moderate to severe hepatic insufficiency.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Below is the list of medicines, which have the same composition, strength and form as Floxsafe 400 MG Tablet , and hence can be used as its substitute.

• Moxam 400 MG Tablet

  Alkem Laboratories Ltd

• M-Cin 400 MG Tablet

  Lupin Ltd

• Newquin 400 MG Tablet

  Cipla Ltd

• Mahaflox 400 MG Tablet

  Mankind Pharmaceuticals Ltd

• Moxigood 400 MG Tablet

  Cadila Pharmaceuticals Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Missed Dose instructions

  The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of overdose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Floxsafe 400 MG Tablet is a fluoroquinolone antibiotic that works by inhibiting the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. This interferes with the bacterial cell replication and repair leading to cell death.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Information not available.

• Interaction with Medicine

  • Drugs which prolong QT interval (including Class Ia and Class III antiarrhythmics, erythromycin, cisapride, antipsychotics, and cyclic antidepressants) are contraindicated with Floxsafe 400 MG Tablet.
  • Metal cations (magnesium, aluminum, iron, and zinc) bind quinolones in the gastrointestinal tract and inhibit absorption (by up to 98%). Antacids, electrolyte supplements, sucralfate, quinapril, and some didanosine formulations should be avoided. Floxsafe 400 MG Tablet should be administered 4 hours before or 8 hours after these agents.
  • Antineoplastic agents may decrease the absorption of quinolones.
  • Cimetidine, and other H2 antagonists may inhibit renal elimination of quinolones.
  • Digoxin levels may be increased in some patients by quinolones; monitor for increased effect/concentrations.
  • Foscarnet has been associated with an increased risk of seizures with some quinolones.
  • Loop diuretics: Serum levels of some quinolones are increased by loop diuretic administration. May diminish renal excretion.
  • NSAIDs: The CNS stimulating effect of some quinolones may be enhanced, resulting in neuroexcitation and/or seizures. This effect has not been observed with Floxsafe 400 MG Tablet.
  • Probenecid: Blocks renal secretion of quinolones, increasing concentrations.
  • Warfarin: The hypoprothrombinemic effect of warfarin is enhanced by some quinolone antibiotics. No significant effect has been demonstrated for Floxsafe 400 MG Tablet, however, monitoring of the INR during concurrent therapy is recommended by the manufacturer.

• Interaction with Disease

  Central Nervous System Depression

  If you suffer from CNS disorder and you take Floxsafe 400 MG Tablet, then you may experience tremors, restlessness, anxiety, confusion and hallucinations. Avoid consuming caffeine containing products like coffee, chocolates and energy drinks.

  Qt Prolongation

  Avoid using Floxsafe 400 MG Tablet if you experience any chest discomfort. Regular cardiac function tests are to be performed if you have any heart disease (arrhythmia) or family history of heart disease.

  Colitis

  Avoid taking Floxsafe 400 MG Tablet if you experience severe diarrhea, abdominal pain, and blood in stools after taking the medicine. Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.

• Interaction with Food

  Information not available.

• Ques : Can the use of Floxsafe 400 MG Tablet increase the risk of muscle damage?

  Ans : Yes, the use of this medicine might increase the risk of muscle damage, commonly in the ankle (Achilles tendon). People of all ages can experience muscle damage who take Floxsafe 400 MG Tablet.

• Ques : Can the use of Floxsafe 400 MG Tablet cause diarrhea?

  Ans : Yes, the use of this medication can cause diarrhea. Being an antibiotic, this drug helps in killing harmful bacteria. If, in case, you are experiencing severe diarrhea, consult your doctor.

• Ques : Can I stop taking Floxsafe 400 MG Tablet when I feel better?

  Ans : No, you must not stop taking this medication. It is suggested to complete the full course of treatment even if you feel better.

• Ques : How long do I need to use Floxsafe 400 MG Tablet before I see improvement in my condition?

  Ans : This medication is to be taken till the time you see an improvement in your health conditions.

• Ques : At what frequency do I need to use Floxsafe 400 MG Tablet?

  Ans : This medication should be taken in the dosage as prescribed by the doctor.

• Ques : Should I use Floxsafe 400 MG Tablet empty stomach, before food or after food?

  Ans : This medication should be taken after food in a prescribed dosage.

• Ques : What are the instructions for the storage and disposal of Floxsafe 400 MG Tablet?

  Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

• Moxifloxacin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 31 May 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/moxifloxacin

• Moxifloxacin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 31 May 2022].Available from:

  https://go.drugbank.com/drugs/DB00218

• MOXIFLOXACIN Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 31 May 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=MOXIFLOXACIN