Fluka 150 MG Tablet

Fluka 150 MG Tablet is primarily prescribed for the treatment of hepatosplenic candidiasis and other Candida infections, cryptococcal infections and secondary prophylaxis for cryptococcal meningitis in persons with AIDS. It is also used as antifungal prophylaxis in allogeneic bone marrow transplant recipients.

This medicine belongs to the class of triazole antifungal. Fluka 150 MG Tablet is effectively used in the treatment of meningitis. It affects the membranes in the brain and spinal cord. This drug treats fungal infections like yeast infections in the mouth, throat, food pipe, lungs, vagina, etc.

It works by decreasing the production of ergosterol, which inhibits cell membrane formation in fungi. This drug is also preferred as a preventive medication in patients susceptible to fungal infections while undergoing chemotherapy or radiation therapy before bone marrow transplantation.

Some serious side effects that may occur and need immediate medical attention are:

• Yellowing of the skin, dark urine, light-coloured stool and itchiness of the skin, indicating liver damage
• Severe rash or peeling of the skin in patients suffering from cancer or AIDS
• Irregular or fast heart rate, palpitations, seizures or fainting, indicating Torsades de Pointes (a condition of abnormal rhythm of the heart which may cause a sudden cardiac arrest)

Symptoms of overdose include decreased lacrimation, salivation, respiration and motility, urinary incontinence, cyanosis. Treatment includes supportive measures, a 3-hour hemodialysis will remove 50%.

Take as directed, around-the-clock. Take full course of medication as ordered. Follow good hygiene measures to prevent reinfection. Frequent blood tests may be required. Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake).

• Oropharyngeal Candidiasis

• Esophageal Candidiasis

• Cryptococcal Meningitis

• Vaginal Candidiasis

• Prophylaxis Of Infections In Special Population

• Fungal Infections (Tinea Strains)

• Allergy

• QT Interval prolonging drugs

• Headache

• Nausea Or Vomiting

• Abdominal Pain

• Diarrhoea

• Skin Rash

• Dizziness

• Hypokalemia

• Vertigo

• Tremor

• Insomnia

• Decreased Appetite

• How long is the duration of effect?

  The effect of this medication lasts for an average of 30 hours.

• What is the onset of action?

  The effect of this medication can be observed within 1-2 hours of administration.

• Are there any pregnancy warnings?

  This drug is extremely unsafe to be used during pregnancy. Studies carried out on humans and animals have shown significant adverse effects on the fetus. Doctor consultation is recommended in such cases.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  The drug should not be consumed by breastfeeding mothers as there is a higher risk of side-effects on the infant. You are suggested to consult your doctor to discuss the potential benefits and risks before taking this medicine.

• Does this affect kidney function?

  Dose adjustment is needed in patients with renal impairment. Consult your doctor before taking Fluka 150 MG Tablet. Dosing adjustment/interval in renal impairment:

  • No adjustment for vaginal candidiasis single-dose therapy.
  • For multiple dosing, administer usual load then adjust daily doses.
  • Clcr 11-50 mL/minute: Administer 50% of recommended dose or administer every 48 hours.
  • Hemodialysis: One dose after each dialysis.
  • Continuous arteriovenous or venovenous hemodiafiltration (CAVH) effects: Dose as for Clcr 10-50 mL/minute.

• Does this affect liver function?

  No relevant information available. Consult your doctor before taking Fluka 150 MG Tablet.

• Is It safe with alcohol?

  Caution is advised in consuming alcohol, if you are taking this medicine. Please consult your doctor.

• Is it safe to drive while on this medicine?

  This medicine causes side effects that affect the alertness of the patients. Thus it influences the driving ability of the patient.

Below is the list of medicines, which have the same composition, strength and form as Fluka 150 MG Tablet , and hence can be used as its substitute.

• Mycosure 150 MG Tablet

  Lupin Ltd

• Zocon 150 MG Tablet

  Fdc Ltd

• Flutas 150 MG Tablet

  Intas Pharmaceuticals Ltd

• Funaz 150 MG Tablet

  Wockhardt Ltd

• Skican 150 MG Tablet

  Leo Pharmaceuticals

• Are there any missed dose instructions?

  The missed dose can be taken as soon as you remember.

• Are there any overdose instructions?

  Inform your doctor immediately if you are experiencing symptoms of overdose.

This medication decreases ergosterol production by disrupting the activity of cytochrome P450, inhibiting the formation of the cell membrane of susceptible fungi like Candida and Microsporum.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Keep monitoring periodic liver function tests (AST, ALT, alkaline phosphatase) and renal function tests, potassium. As these might drastically be affected by the action of the Fluconazole.

• Interaction with Medicine

  • Increased effect/toxicity:
  • Coadministration with terfenadine or cisapride is contraindicated; use with caution with astemizole due to increased risk of significant cardiotoxicity.
  • Hydrochlorothiazide may decrease fluconazole clearance.
  • Fluconazole may also inhibit warfarin, phenytoin, cyclosporine, and theophylline, zidovudine, sulfonylureas, rifabutin, and warfarin clearance.
  • Nephrotoxicity of tacrolimus may be increased.
  • Should be used with caution in patients receiving cisapride or astemizole.

• Interaction with Disease

  Should be used with caution in patients with renal and hepatic dysfunction or previous hepatotoxicity from other azole derivatives. Patients who develop abnormal liver function tests during fluconazole therapy should be monitored closely and discontinued if symptoms consistent with liver disease develop.

• Interaction with Food

  No data reported.

• Ques : What is Fluka 150 MG Tablet?

  Ans : This medication belongs to the class of antifungal drugs. It works by killing fungi by destroying the fungal cell membrane.

• Ques : What are the uses of Fluka 150 MG Tablet?

  Ans : This tablet is used for the treatment and prevention from conditions like oropharyngeal candidiasis, esophageal candidiasis, cryptococcal meningitis, vaginal candidiasis, etc.

• Ques : What are the Side Effects of Fluka 150 MG Tablet?

  Ans : Headache, nausea and, vomiting, abdominal pain, diarrhea, skin rash, etc are common side effects.

• Ques : What are the instructions for storage and disposal Fluka 150 MG Tablet?

  Ans : This tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Ques : Is Fluka 150 MG Tablet safe to use when pregnant?

  Ans : This medication is not recommended for use in pregnant women unless absolutely necessary.

• Ques : Will Fluka 150 MG Tablet be more effective if taken in more than the recommended dose?

  Ans : No, taking higher than the recommended dose of this medicine can lead to increased chances of side effects.

• Ques : Can Fluka 150 MG Tablet be taken with oral contraceptives (OCPs) or birth control pills?

  Ans : Fluka 150 MG Tablet may interact with oral contraceptives having ingredients like estradiol. Hence, consult a doctor before taking them together.

• Ques : I feel better now, can I stop taking Fluka 150 MG Tablet?

  Ans : It is important to finish the course of treatment, hence one must not stop taking this drug if they start feeling better. If you stop taking it without any doctor consultation, then it may severely affect your medical condition.

• Ques : Is Fluka 150 MG Tablet safe to be used in pregnancy?

  Ans : This drug is not suitable for pregnant women as it can harm the baby. Consult a doctor and use some other alternative to this drug.

• Ques : Can Fluka 150 MG Tablet cause hair loss?

  Ans : Hair loss is a very unusual side effect of this medicine. If you encounter this symptom, then doctor consultation is suggested.

• Ques : Is Fluka 150 MG Tablet fungistatic or fungicidal?

  Ans : Fluka 150 MG Tablet is a fungistatic medication and helps in inhibiting the growth or bacteria. It also functions as a fungicidal (kills fungus) medicine against some specific organisms.

• Ques : Is Fluka 150 MG Tablet over the counter (OTC)?

  Ans : No, this medication is not available as an over the counter (OTC) drug. You must only take it if this medicine is prescribed by a healthcare professional.

• Ques : What if I forget to take a dose of Fluka 150 MG Tablet?

  Ans : Take the missed dose as soon as possible, however, skip the missed dose if it is almost the time for the next dose.

• Ques : Is Fluka 150 MG Tablet effective?

  Ans : It is an effective medication, however, you must consume it in dose and duration suggested by a medical expert.

• Ques : Does Fluka 150 MG Tablet treat bacterial vaginosis?

  Ans : This drug is not helpful against bacterial vaginosis. If you are suffering from bacterial vaginosis, do not take this drug, rather talk to a doctor to start a treatment.

• Ques : Does Fluka 150 MG Tablet make you feel tired?

  Ans : Tiredness is a common side effect reported after consumption of this medicine. You may want to take rest after consuming this medicine.

• Ques : Is Fluka 150 MG Tablet a steroid?

  Ans : This medicine is not a steroid, in fact it is an antifungal drug.

• Ques : Can I take Fluka 150 MG Tablet for yeast infection?

  Ans : This medication can be taken for a yeast infection. Please consult a doctor before taking it.

• Fluconazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 23 Nov 2021]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/fluconazole

• Azocan-P Capsules 150mg- EMC [Internet]. www.medicines.org.uk. 2020 [Cited 23 Nov 2021]. Available from:

  https://www.medicines.org.uk/emc/product/4960/smpc

• FLUCONAZOLE tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2019 [Cited 23 Nov 2021]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5590e3fc-b9a1-4863-9420-900bf437a3cc