Grefac 60 MG Injection

Grefac 60 MG Injection is primarily used for the prevention of deep vein thrombosis following hip or knee replacement surgery or abdominal surgery in patients at risk for thromboembolic complications.

It is also used for inpatient treatment of acute deep vein thrombosis with and without pulmonary embolism when administered in conjunction with warfarin sodium; outpatient treatment of acute deep vein thrombosis without pulmonary embolism when administered in conjunction with warfarin sodium.

Grefac 60 MG Injection is also helpful in the prevention of ischemic complications of unstable angina and non-Q wave myocardial infarction (when administered with aspirin).

Grefac 60 MG Injection is used for thinning your blood and preventing the formation of clots. It is generally used if you are recuperating at home after a stomach, knee or hip surgery when it is difficult for you to move around.

This drug is available in solution form which is injected in your body. While injecting this drug, it may result in a bruise and pain in area where it is being injected initially.

The dosage depends on your age, general health condition and the reaction of your body to the first dose. Ensure that you do not stop taking the medicine abruptly as that would increase the risk of getting a blood clot.

This drug can only be administered by injection. You may have a tendency to bleed easily while taking this drug; brush teeth with soft brush, floss with waxed floss, use electric razor, avoid scissors or sharp knives, and potentially harmful activities.

Report chest pain; persistent constipation; persistent erection; unusual bleeding or bruising (bleeding gums, nosebleed, blood in urine, dark stool); pain in joints or back; or numbness, tingling, swelling, or pain at injection site.

Symptoms of Grefac 60 MG Injection overdose include hemorrhage. Protamine sulfate has been used to reverse effects.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

• Prophylaxis For Deep Vein Thrombosis

• Prophylaxis For Angina And Myocardial Infarction

• Deep Vein Thrombosis Prophylaxis After Surgery

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

• Hypersensitivity

• Thrombocytopenia

• Bleeding Disorders

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

• Fever

• Confusion

• Pain

• Nausea

• Increased Liver Enzymes

• Local Reaction

• Urticaria

• Pruritus

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 12 hours.

• What is the onset of action?

  The peak effect of this medicine can be observed in 3 to 5 hours.

• Are there any pregnancy warnings?

  This medicine is recommended for pregnant women only if clearly needed. Careful monitoring of any symptoms of bleeding is necessary.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  In case of breastfeeding, you must consult the doctor.

• Does this affect liver function?

  This medication should be used with caution if the patient is suffering from hepatic impairment.

• Does this affect kidney function?

  This medication is not recommended for patients with end stage renal diseases. Total clearance is lower and elimination is delayed in patients with renal failure; adjustment may be necessary in elderly and patients with severe renal impairment.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

Below is the list of medicines, which have the same composition, strength and form as Grefac 60 MG Injection , and hence can be used as its substitute.

• Angionox 60 MG Injection

  Zydus Cadila

• Lonopin 60 MG Injection

  Bharat Serums & Vaccines Ltd

• Lmwx 60 MG Injection

  Abbott Healthcare Pvt. Ltd

• Xparin 60 MG Injection

  Astrazeneca Pharma India Ltd

• Isonorm 20 MG Tablet

  Lupin Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

• Are there any missed dose instructions?

  Missed dose should be taken as soon as possible. It is recommended to skip your missed dose, if it is the time for your next scheduled dose.

• Are there any overdose instructions?

  Consult your doctor in case of overdose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

This medication belongs to the anticoagulants. It works by binding to antithrombin III which inhibits the formation of clotting factors IIa and Xa thus prevent the blood from clotting.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Lab Test

  No information available.

• Interaction with Medicine

  • Drugs which affect platelet function (eg, aspirin, NSAIDs, dipyridamole, ticlopidine, clopidogrel) may potentiate the risk of hemorrhage.
  • Thrombolytic agents increase the risk of hemorrhage.
  • Warfarin: Risk of bleeding may be increased during concurrent therapy. Enoxaparin is commonly continued during the initiation of warfarin therapy to assure anticoagulation and to protect against possible transient hypercoagulability.

• Interaction with Food

  Information not available.

• Interaction with Disease

  Consider risk versus benefit prior to neuraxial anesthesia; risk is increased by concomitant agents which may alter hemostasis, as well as traumatic or repeated epidural or spinal puncture. Patient should be observed closely for bleeding if enoxaparin is administered during or immediately following diagnostic lumbar puncture, epidural anesthesia, or spinal anesthesia.

• Ques : What is Grefac 60 MG Injection?

  Ans : This drug is used to treat clotting of blood.

• Ques : How long do I need to use Grefac 60 MG Injection before I see improvement in my condition?

  Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 day to 1 week. Please consult your doctor for the time period you need to use this medication.

• Ques : At what frequency do I need to use Grefac 60 MG Injection?

  Ans : This medication is generally used once or twice a day. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

• Ques : What are the instructions for the storage and disposal of Grefac 60 MG Injection?

  Ans : Store Grefac 60 MG Injection injections at 25°C and do not freeze them. The multiple-dose vials should not be stored for more than 28 days after the first use. Read the medicine package leaflet before using this medication and ask the pharmacist in case of any doubt.

• Ques : Should I use Grefac 60 MG Injection empty stomach, before food or after food?

  Ans : This medication is advised to be consumed orally. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

• Ques : How do you administer Grefac 60 MG Injection?

  Ans : Grefac 60 MG Injection is a medicine which is injected beneath the skin. Fix the dose of the medicine and pinch the skin of your stomach between your finger and thumb to make a fold. After having cleaned the area, hold the syringe like a pencil and insert the full length of the needle into the skin fold. Inject the medicine and discard the syringe as instructed by your prescribing physician. Follow the instructions given by the doctor strictly or contact your doctor in case of any doubt or any reactions associated with the medicine.

• Ques : Can Grefac 60 MG Injection be used in heart attack?

  Ans : Yes, Grefac 60 MG Injection is used in the treatment of chest pain and heart attack once the standard treatment has been provided to the patient. It is given along with another blood thinner like aspirin. Being a blood-thinning agent, it prevents the blood from clotting and prevents any further episodes and complications.

• Ques : When will I feel better after taking Grefac 60 MG Injection?

  Ans : Grefac 60 MG Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Grefac 60 MG Injection. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.

• Enoxaparin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/enoxaparin

• Enoxaparin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 2 June 2022].Available from:

  https://go.drugbank.com/drugs/DB01225

• ENOXAPARIN injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=ENOXAPARIN