Griseofulvin
About Griseofulvin
Griseofulvin is an antifungal medication used to cure fungal infections of the hair, skin and nails. Griseofulvin works by not only preventing the fungal infection from spreading to new cells but also arrests the infection causing fungus from multiplying.
The common side effects that come with taking this drug include skin rashes, nausea, heartburn, diarrhea, dizziness, clouded thoughts, headache, signs of insomnia and numbness in various parts of the body. If these effects keep on persisting with no signs of leaving, then seek help from your doctor immediately.
This drug can cause serious effects which can prove to be fatal in the long run. These serious reactions comprise of swelling, fever, blisters, marked decrease in appetite, joint pain and constant feelings of fatigue. Should such an instance occur seek help immediately.
Certain conditions under which it is advised that you should refrain from taking this drug, if you have or are:
- Allergic to the medication.
- A history of porphyria or liver failure.
- A history of lupus.
- Pregnant, are planning to become pregnant or are breastfeeding.
- Under any kind of medications, be it prescriptive or non-prescriptive and herbal.
- Ensure not to conceive while you are taking this drug and also for at least six months after stopping it.
- Taking hormonal pills as contraception.
The recommended dose for adults ranges between 500-1000 mg every day. Children are prescribed a low-power dose of about 125 mg depending on the height, weight and overall health. Make sure to take this drug only after you have had some food whether it is your full-fledged meal or a light snack.
Food substance in your stomach helps to absorb this drug better. In case of a missed dose, take it as soon as you recall it. If it is too late and already time for your next dose, do not overdose, skip the previous missed one entirely. In case of an instance of drug overdose contact your physician right away.
Take as directed; around-the-clock with food. Take full course of medication; do not discontinue without notifying your prescriber. Avoid alcohol while taking this drug (disulfiram reactions). Symptoms of overdose include lethargy, vertigo, blurred vision, nausea, vomiting, diarrhea.
Practice good hygiene measures to prevent reinfection. Frequent blood tests may be required with prolonged therapy. Report skin rash, respiratory difficulty, CNS changes (confusion, dizziness, acute headache), changes in color of stool or urine, white plaques in mouth, or worsening of condition.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.
What are the uses of Griseofulvin
Fungal Infections (Tinea Strains)
This medicine is used for the treatment of fungal infections of the scalp, hair, skin, toenails, crotch, thighs, skin caused by tinea strains of fungi.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.
What are the side effects of Griseofulvin ?
Urticaria
Headache
Mental Confusion
Photosensitivity
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.
Key highlights of Griseofulvin
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 2 days.
What is the onset of action?
The effect of this medicine can be observed within 4-5 hours of oral administration.
Are there any pregnancy warnings?
Use of this medicine by pregnant women is not recommended unless absolutely necessary. Consult your doctor before taking this medicine.
Is it habit forming?
No habit forming tendencies were reported.
Are there any breast-feeding warnings?
Use of this medicine by women who are breastfeeding is not recommended. Your doctor may prescribe a safer alternative if needed.
Is It safe with alcohol?
Consumption of alcohol is found to be unsafe while taking this medicine.
Is it safe to drive while on this medicine?
This medicine might affect the alertness of the patient, thus driving must be avoided while taking this medicine.
Does this affect kidney function?
This medicine is probably safe to be used in patients with kidney disease. Available limited data suggests that adjustment of dose is not required. Kindly consult your doctor before taking it.
Does this affect liver function?
Caution must be taken in patient with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.
What are the dosage instructions?
Missed Dose instructions
Take the missed dose as soon as you remember. The missed dose can be skipped if the next scheduled dose is less than two hours away.
Are there any overdose instructions?
Contact your doctor immediately if an overdose with this medicine is suspected.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.
Where is the Griseofulvin approved?
India
United States
Japan
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.
Medicines containing Griseofulvin
Below is the list of medicines, which contains Griseofulvin as ingredient
- Grisovin Fp 250 MG Tablet
Glaxosmithkline Pharmaceuticals Ltd
- Fulvinem 500 MG Tablet
Medo Pharma
- Walavin 250 MG Tablet
Wallace Pharmaceuticals Ltd
- Dermonorm 500 MG Tablet
Glaxosmithkline Pharmaceuticals Ltd
- Grisactin Forte 250 MG Tablet
Adcock Ingram Healthcare Pvt Ltd
- Gris Od 250 MG Tablet
Dr. Reddys Laboratories Ltd
- Fungal 150 MG Tablet
Inga Laboratories Pvt. Ltd
- Griseoderm 375 MG Tablet
Litaka Pharmaceuticals Ltd
- Grisomed 375 MG Tablet
Comed Chemicals Pvt Ltd
- Dermonorm 250 MG Tablet
Glaxosmithkline Pharmaceuticals Ltd
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.
How does this medication work?
This medication works by inhibiting fungal cell wall division by disrupting the mitotic spindle structure and also interferes with DNA production. It binds to keratin present in human skin and provides temporary resistance to fungal infections.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.
What are the interactions of Griseofulvin ?
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
- test
Interaction with Alcohol
Interaction with Lab Test
Interaction with Medicine
- Decreased effect:
- Barbiturates may decrease levels of griseofulvin
- Decreased warfarin, cyclosporine, and salicylate activity with griseofulvin
- Griseofulvin decreases oral contraceptive effectiveness
- Increased toxicity: With alcohol tachycardia and flushing
Interaction with Food
Interaction with Disease
FAQs about Griseofulvin
Ques : What if I forget to take a dose of Griseofulvin?
Ans : If you forget a dose of Griseofulvin, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Ques : Is Griseofulvin effective?
Ans : Griseofulvin is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition.
Ques : Is Griseofulvin a steroid?
Ans : No, Griseofulvin is not a steroid. It is a medicine which is used to kill a wide variety of infection-causing fungus. It is applied on the affected skin or nails to treat fungal infections of the skin and nails.
Ques : Can Griseofulvin cause any local reaction or rashes?
Ans : Yes, the use of Griseofulvin may cause allergic reactions, but the probability is unknown. Such allergic reaction is not very common and is likely to occur in only susceptible or sensitive individuals. Immediately contact your doctor if you experience such reactions.
Ques : Is Griseofulvin safe?
Ans : Yes, the medication is safe, if used in the dose and duration advised by your doctor.
References
Griseofulvin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 4 June 2022].Available from:
https://druginfo.nlm.nih.gov/drugportal/name/griseofulvin
Griseofulvin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 4 June 2022].Available from:
https://go.drugbank.com/drugs/DB00400
GRISEOFULVIN tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 4 June 2022].Available from:
https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=GRISEOFULVIN
Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.
Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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