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Overview

Haloperidol

Prescription vs OTC : Prescription by Doctor required

About Haloperidol

Haloperidol is a medication that is used in the treatment of mental disorders such as mood behavior disorders, schizophrenia and schizoaffective disorders and hallucinations. It has also shown to reduce aggression and the desire to commit suicide or bring harm to others.

On using Haloperidol some side effects may occur which are; diarrhea, dizziness, drowsiness, headache, decrease in appetite, headache, stomach upset, restlessness and nausea. Take precaution by informing your physician if:

  • You are pregnant or thinking about becoming pregnant.
  • You are breastfeeding a baby.
  • You are under any kind of medication, prescriptive, over the counter, herbal, vitamins or dietary supplements.
  • You are allergic to any medicine or food.
  • You have a history of heart diseases.
  • You have porphyria or low blood pressure.
  • You have a history of dementia, Alzheimer disease or seizures.
  • You are alcoholic.

Seek help from your health care provider if the following severe side effects manifests and continues; allergic skin reactions, fuzzy vision, difficulty in speech, uncontrolled sweating, rapid heartbeat, trouble breathing, darkening of your urine, fever, stiffening of muscles, decreased libido, reduced sperm production and enlargement of breasts .

Haloperidol needs to be injected into your body. It should be done by trained hands. Do not buy the medication if it is discoloured or slightly cloudy. If you miss one of your doses try to take it as soon as possible. But do not overdose by clubbing the two at the same time.

When you are on Haloperidol do not drink alcohol. Avoid exposure to the sun or extreme heat. Keep this medication stored between 15 to 30 degrees C. It should be kept away from the reach of children.

Use exactly as directed (do not increase dose or frequency); may cause physical and/or psychological dependence. It may take 2-3 weeks to achieve desired results; do not discontinue without consulting prescriber.

Dilute oral concentration with water or juice. Do not take within 2 hours of any antacid. Store away from light. Avoid excess alcohol or caffeine and other prescription or OTC medications not approved by prescriber.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). Avoid skin contact with medication; may cause contact dermatitis (wash immediately with warm, soapy water).

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    What are the uses of Haloperidol

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    What are the contraindications of Haloperidol ?

    • Allergy

      Not recommended in patients with known allergy to Haloperidol

    • Central Nervous System Depression

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    What are the side effects of Haloperidol ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    Key highlights of Haloperidol

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 2 to 4 weeks

    • What is the onset of action?

      The effect of this medicine can be observed in 30 to 60 minutes after an intravenous or intramuscular dose

    • Are there any pregnancy warnings?

      This medicine is not recommended for pregnant women. Use only if clearly needed when no safer alternative is available.

    • Is it habit forming?

      No habit forming tendency has been reported

    • Are there any breast-feeding warnings?

      This medicine is known to be excreted in human breast milk. It is not recommended for breastfeeding women. Use only if clearly needed when no safer alternative is available.

    • Is It safe with alcohol?

      It is found to be unsafe to consume alcohol while taking this medicine.

    • Is it safe to drive while on this medicine?

      This drug might affect the consciousness of the patient. Thus patient must avoid driving while taking this medicine.

    • Does this affect kidney function?

      Limited information is available regarding its use in patient with kidney disease. Kindly consult your doctor before taking it.

    • Does this affect liver function?

      Limited information is available regarding its use in patient with liver disease. Kindly consult your doctor before taking it.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    Where is the Haloperidol approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    Medicines containing Haloperidol

    Below is the list of medicines, which contains Haloperidol as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    How does this medication work?

    Haloperidol belongs to the class antipsychotics. It works by binding to the dopamine D2 receptors and inhibits the release of chemical substances thus helps in reducing the symptoms.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

      What are the interactions of Haloperidol ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Alcohol

        Consumption of alcohol with this medicine is not recommended as it can result in dizziness and difficulty in concentration. Avoid activities that need mental alertness like driving and operating machinery.

        Consumption of alcohol with this medicine is not recommended as it can result in dizziness and difficulty in concentration. Avoid activities that need mental alertness like driving and operating machinery.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Medicine

        • Benztropine (and other anticholinergics) may inhibit the therapeutic response to Haloperidol and excess anticholinergic effects may occur.
        • Chloroquine may increase Haloperidol concentrations.
        • Cigarette smoking may enhance the hepatic metabolism of Haloperidol. Larger doses may be required compared to a nonsmoker.
        • Concurrent use of Haloperidol with an antihypertensive may produce additive hypotensive effects.
        • Concurrent use with TCA may produce increased toxicity or altered therapeutic response.
        • Haloperidol may inhibit the antiparkinsonian effect of levodopa; avoid this combination.
        • Haloperidol plus lithium may rarely produce neurotoxicity.
        • Barbiturates may reduce Haloperidol concentrations.
        • Propranolol may increase Haloperidol concentrations.
        • Sulfadoxine-pyrimethamine may increase Haloperidol concentrations.
        • Haloperidol and CNS depressants (ethanol, narcotics) may produce additive CNS depressant effects.
        • Haloperidol and trazodone may produce additive hypotensive effects.
        • Carbamazepine appears to stimulate the metabolism of Haloperidol. Monitor for reduced efficacy.
        • Fluoxetine and paroxetine may inhibit the metabolism of Haloperidol resulting in EPS; monitor for EPS.
        • Haloperidol in combination with indomethacin may result in drowsiness, tiredness, and confusion; monitor for adverse effects.
        • Quinidine appears to increase Haloperidol concentrations; monitor for EPS.
      • Interaction with Food

        Food

        Information not available.
      • Interaction with Disease

        • Hypotension may occur, particularly with parenteral administration. Decanoate form should never be administered I.V. Avoid in thyrotoxicosis. May be sedating, use with caution in disorders where CNS depression is a feature.
        • Caution in patients with hemodynamic instability, predisposition to seizures, subcortical brain damage, renal or respiratory disease. Esophageal dysmotility and aspiration have been associated with antipsychotic use - use with caution in patients at risk of pneumonia (ie, Alzheimer's disease).
        • Caution in breast cancer or other prolactin-dependent tumors (may elevate prolactin levels). May alter temperature regulation or mask toxicity of other drugs due to antiemetic effects.
        • May alter cardiac conduction - life-threatening arrhythmias have occurred with therapeutic doses of antipsychotics. Adverse effects of decanoate may be prolonged.
        • May cause orthostatic hypotension - use with caution in patients at risk of this effect or those who would tolerate transient hypotensive episodes (cerebrovascular disease, cardiovascular disease, or other medications which may predispose). Some tablets contain tartrazine.
        • May cause extrapyramidal reactions, including pseudoparkinsonism, acute dystonic reactions, akathisia, and tardive dyskinesia (risk of these reactions is high relative to other neuroleptics). May be associated with neuroleptic malignant syndrome (NMS) or pigmentary retinopathy.

      FAQs about Haloperidol

      • Ques : Is Haloperidol a controlled drug or narcotic or addictive?

        Ans : No,Haloperidol is not a controlled drug, narcotic or addictive.

      • Ques : Is Haloperidol a benzo or a neuroleptic or MAOI?

        Ans : No,Haloperidol is not benzo or MAOI or a neuroleptic. It is antipsychotic. It works by blocking the action of dopamine receptors in brain, which decreases the excessive dopamine activity in the brain.

      • Ques : Is Haloperidol used for nausea?

        Ans : No,Haloperidol is not used for nausea.

      • Ques : Is Haloperidol a sedative/ make you sleepy?

        Ans : Yes,Haloperidol can cause sedation.

      • Ques : Can you take Haloperidol with lorazepam?

        Ans : Haloperidol interacts with lorazepam to cause increased sedation and impaired attention. Please consult your doctor before taking Haloperidol with diazepam.

      • Ques : Does Haloperidol cause weight gain or does Haloperidol cause tardive dyskinesia?

        Ans : Yes, in some people Haloperidol may cause weight gain and tardive dyskinesia

      • Ques : Does Haloperidol cause respiratory depression/ hallucination?

        Ans : Haloperidol may cause dyspnea as well as other behavioral abnormalities in patients. It is not known to cause respiratory depression/ hallucination.

      References

      • Haloperidol-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 4 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/haloperidol

      • Haloperidol-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 4 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00502

      • HALOPERIDOL tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 4 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=HALOPERIDOL

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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