Isosorbide-5-Mononitrate

Isosorbide-5-Mononitrate is primarily used to avoid an angina attack. It widens blood vessels allowing increased blood flow to the heart. This medicine falls under the category of drugs called nitrates. It is sold under different trade names in different countries.

• If you are allergic to any of the ingredients contained within Isosorbide-5-Mononitrate.
• If you are taking any prescription or non-prescription drugs, vitamins or dietary supplements.
• If you are taking any erectile dysfunction medications.
• If you have a history of heart diseases or warnings of a possible heart attack.
• If you have low blood pressure.
• If you have kidney disease.
• You are pregnant, or are planning to become pregnant or are breastfeeding.

Take this medicine as a whole. Follow the dosage as prescribed by your doctor. Normal dosage requires you to have this medication once daily, usually after waking up in the morning. In some other cases, you may need to have a second dose later on in the day.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Angina Pectoris Prophylaxis

  This medicine is used for the prevention of angina (chest pain) caused due to reduced flow of blood and oxygen to the heart. It is not effective in treating chest pain that has already set in.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Allergy

  This medicine is not recommended for use if you have a known history of allergy to this medication or any nitrate-containing medicines.

• Anemia

  This medicine is not recommended for use if you have anemia or low levels of hemoglobin in the blood.

• Obstructive Heart Disease

  This medicine is not recommended for use if you have a condition where the blood vessels in the heart have blockage due to swelling or narrowing.

• Head Trauma/Increased Intracranial Pressure

  This medicine is not recommended for use in patients having a severe head injury or the pressure in the brain is elevated.

• Medicine for erectile dysfunction

  This medicine is not recommended for use if you are taking medicines for the treatment of erectile dysfunction. One of the most commonly used medicines for this condition is Viagra (sildenafil),

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Low Blood Pressure

• Dizziness

• Headache

• Nausea Or Vomiting

• Fainting

• Tachycardia

• Diarrhoea

• Rash

• Pruritus

• Myalgia

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 6-8 hours upon oral administration in the form of conventional tablets.

• What is the onset of action?

  The effect of this medicine can be observed within 20-30 of oral administration. However, this time is subject to vary depending on the form of the medicine.

• Are there any pregnancy warnings?

  This medicine is not recommended for use by pregnant women unless absolutely necessary and the benefits outweigh the risks involved.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not recommended for use by women who are breastfeeding.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Missed Dose instructions

  Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for the next scheduled dose.

• Are there any overdose instructions?

  Contact your doctor immediately if an overdose with this medicine is suspected. Symptoms of an overdose may include a severe headache, fever, nausea, vomiting, difficulty in breathing, excessive sweating etc.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

Below is the list of medicines, which contains Isosorbide-5-Mononitrate as ingredient

• Monit 50 MG Tablet

  Intas Pharmaceuticals Ltd

• Imdur 60 MG Tablet

  Astrazeneca Pharma India Ltd

• Nitrofirst 60 MG Tablet

  Zyphars Pharmaceutics Pvt. Ltd

• Isonorm 10 MG Tablet

  Lupin Ltd

• Imnit 30 MG Tablet

  Dr. Reddys Laboratories Ltd

• Natriem 60 MG Tablet

  Emcure Pharmaceuticals Ltd

• Monosorbitrate 40 MG Tablet

  Abbott Healthcare Pvt. Ltd

• Monocontin 50 MG Tablet

  Win-Medicare Pvt. Ltd

• Oncid 20 MG Capsule

  Bayer Pharmaceuticals Pvt. Ltd

• Monotrate 50 MG Tablet

  Sun Pharma Laboratories Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

This medicine, chemically is an Isosorbide-5-Mononitrate, which gets converted to nitric oxide (NO) free radicals in the body which relax the blood vessels and reduces the load on the heart. This results in an improved blood flow and reduced oxygen demand.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Ethanol

  Avoid or limit the uptake of alcohol while using this medicine. Contact your doctor if you experience excessive sweating, dizziness, confusion after taking this medicine.

• Interaction with Medicine

  Amitriptyline

  Report the use of either of the medicines to the doctor. You may need a dose adjustment and more frequent monitoring of blood pressure levels while using these medicines together.

  Amlodipine

  Report the use of amlodipine or any other medicine taken for lowering the blood pressure to the doctor. You may need a dose adjustment and more frequent monitoring of blood pressure levels while using these medicines together.

  Prilocaine

  Report the use of either of the medicine to the doctor. Your doctor may prescribe suitable alternatives that do not interact with each other. Do not stop the use of any medicine without consulting your doctor.

  Sildenafil

  Report the use of sildenafil or any other medicine taken for erectile dysfunction to the doctor. The risk of adverse effects is significantly high while using these medicines together. Your doctor may determine the best course of treatment in such cases.

  Riociguat

  Report the use of either of the medicine to the doctor. Your doctor may prescribe suitable alternatives that do not interact with each other. Do not stop the use of any medicine without consulting your doctor.

• Interaction with Disease

  Acute myocardial infarction

  This medicine should be used with extreme caution in patients suffering from a heart attack or heart failure. The use should be preceded by suitable clinical examinations to ensure safe and effective use.

  Hypotension

  This medicine should be used with extreme caution in patients who have low blood pressure. The risk of further lowering of blood pressure and associated adverse effects are significantly high.

  Glaucoma

  This medicine should be used with caution in patients suffering from glaucoma. It should be prescribed only after accessing the condition and making suitable adjustments in dosage.

• Interaction with Food

  Licorice

  Avoid or limit the use of licorice while taking this medicine. The risk of adverse effects is higher while using them together. Contact your doctor if you experience excessive sweating, dizziness, confusion after taking this medicine with licorice.

• Ques : What is Isosorbide-5-Mononitrate?

  Ans : This medication widens blood vessels allowing for an increase of blood flow to the heart. It is also used to avoid an angina attack.

• Ques : How long do I need to use Isosorbide-5-Mononitrate before I see improvement in my condition?

  Ans : This medication is to be taken till the time you see an improvement in your health conditions.

• Ques : At what frequency do I need to use Isosorbide-5-Mononitrate?

  Ans : Normal dosage requires you to have this medication once daily, usually after waking up in the morning.

• Ques : Should I use Isosorbide-5-Mononitrate empty stomach, before food or after food?

  Ans : This medication should be taken with or without food in a prescribed dosage.

• Ques : What are the instructions for the storage and disposal of Isosorbide-5-Mononitrate?

  Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

• Isosorbide mononitrate- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 6 December 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/isosorbide-5-mononitrate

• Isosorbide mononitrate- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 6 December 2019]. Available from:

  https://www.drugbank.ca/drugs/DB01020

• Carmil XL 60 mg Tablets- EMC [Internet] medicines.org.uk. 2018 [Cited 6 December 2019]. Available from:

  https://www.medicines.org.uk/emc/product/7997/smpc