Isosorbide Dinitrate

Isosorbide Dinitrate is primarily used for the prevention and treatment of chest pain or angina pectoris and also to treat congestive heart failure. This medicine is also helpful to relieve pain, dysphagia, and spasm in esophageal spasm with GE reflux.

Doctors may either prescribed the medicine all but itself or with a combination of other drugs. Being a nitrate, the drug effectively relaxes blood vessels of the body, which in turn reduces stress on the heart. As a result, the heart required less oxygen, and chest pain is reduced.

Doctors generally do not advice the use of Isosorbide Dinitrate if you are allergic to any substances that are present in the drug. Also, make sure that you inform your doctor about any health problems that you are currently suffering from. They may include thyroid or heart issues, trauma in the head, anemia or internal brain bleeding.

You can take Isosorbide Dinitrate orally with water. It should be consumed while your stomach is empty. In case you happen to miss a dose, ensure that you take the drug immediately when you remember. But if it is time to take the next dose, do not take 2 doses together. Just skip one dose and carry on with your normal dosage schedule.

Patients using Isosorbide Dinitrate should take some precautions to prevent further complications. For instance, alcohol consumption should be avoided as it can lead to hypotension. As patients taking Isosorbide Dinitrate generally experience some amount of dizziness, it is advised that they do not drive or use any heavy form of machinery on their own. Also take heed when you are sitting down or standing up, do it as slowly as possible.

Drugs do result in some side effects, but in most cases, patients do not really experience them or suffer from very minor issues. Some common side effects that can occur because of Isosorbide Dinitrate are light-headedness, headaches and a warm sensation on the face and neck. An allergic reaction may occur with symptoms like severe itching, rashes and hives. In this case, you should seek medical help immediately.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Angina Pectoris

  This medicine is used for the prevention of angina (chest pain) caused due to reduced flow of blood and oxygen to the heart. It is not effective in treating an acute episode of chest pain that has already set in.

• Heart Failure

  This medicine is also used for the treatment of heart failure caused due to failure of bottom left compartment of the heart.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Allergy

• Anemia

• Head Trauma/Increased Intracranial Pressure

• Medicine for erectile dysfunction

• Closed-Angle Glaucoma

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Headache

• Light Headedness

• Syncope

• Dizziness

• Restlessness

• Nausea

• Vomiting

• Bowel Incontinence

• Urinary Incontinence

• Weakness

• Blurred Vision

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 4-6 hours upon oral administration in the form of conventional tablets. The sublingual form remains effective for 2 hours.

• What is the onset of action?

  The effect of this medicine can be observed within 20-30 of oral administration. The sublingual form starts to act within 2-5 minutes of administration.

• Are there any pregnancy warnings?

  This medicine is not recommended for use by pregnant women unless absolutely necessary and the benefits outweigh the risks involved. Consult your doctor before using this medicine if you are pregnant or planning a pregnancy in near future.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not recommended for use by women who are breastfeeding. Your doctor may prescribe an alternate medicine or ask you to stop breastfeeding if the medicine has to be used.

• Is It safe with alcohol?

  It is unsafe to consume alcohol with this medicine.

• Is it safe to drive while on this medicine?

  This medicine usually does not affect the patients ability to drive.

• Does this affect kidney function?

  This medicine is probably safe to be used in patients with kidney disease. Availability of limited information restricts the knowledge whether to adjust the dose or not. Kindly consult your doctor before taking it.

• Does this affect liver function?

  This medicine is probably safe to be used in patients with liver disease. Availability of limited information restricts the knowledge whether to adjust the dose or not. Kindly consult your doctor before taking it.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Missed Dose instructions

  Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for the next scheduled dose.

• Are there any overdose instructions?

  Contact your doctor immediately if an overdose with this medicine is suspected. Symptoms of an overdose may include a severe headache, fever, nausea, vomiting, difficulty in breathing, excessive sweating etc.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

Below is the list of medicines, which contains Isosorbide Dinitrate as ingredient

• Isolazine Tablet

  Lupin Ltd

• Isordil 5Mg Tablet

  Ipca Laboratories Ltd

• Isordil 10Mg Tablet

  Ipca Laboratories Ltd

• Cardicap 10Mg Tablet

  Sun Pharmaceutical Industries Ltd

• Dinospray 20Mg Spray

  Cipla Ltd

• Cardicap 20Mg Capsule Tr

  Sun Pharmaceutical Industries Ltd

• Sorbidine 10Mg Tablet

  Troikaa Pharmaceuticals Ltd

• Sorbitrate 10Mg Tablet

  Abbott India Ltd

• Cordil 5Mg Tablet

  Prevento Pharma

• Sorbitrate 5Mg Tablet

  Abbott India Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

The active constituent of this medication gets converted to nitric oxide (NO) free radicals in the body which relax the blood vessels and reduces the load on the heart. This results in improved blood flow and reduced oxygen demand.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Alcohol

  Avoid or limit the uptake of alcohol while using this medicine. Contact your doctor if you experience excessive sweating, dizziness, confusion after taking this medicine.

• Interaction with Lab Test

  This medicine decrease the cholesterol of the patient.

• Interaction with Medicine

  Amitriptyline

  Report the use of either of the medicines to the doctor. You may need a dose adjustment and more frequent monitoring of blood pressure levels while using these medicines together.

  Amlodipine

  Report the use of amlodipine or any other medicine taken for lowering the blood pressure to the doctor. You may need a dose adjustment and more frequent monitoring of blood pressure levels while using these medicines together.

  Prilocaine

  Report the use of either of the medicine to the doctor. Your doctor may prescribe suitable alternatives that do not interact with each other. Do not stop the use of any medicine without consulting your doctor.

  Sildenafil

  Report the use of sildenafil or any other medicine taken for erectile dysfunction to the doctor. The risk of adverse effects is significantly high while using these medicines together. Your doctor may determine the best course of treatment in such cases. As a significant reduction of systolic and diastolic blood pressure with concurrent use. Sildenafil must not be given within 24 hours of a nitrate preparation.

  Riociguat

  Report the use of either of the medicine to the doctor. Your doctor may prescribe suitable alternatives that do not interact with each other. Do not stop the use of any medicine without consulting your doctor.

• Interaction with Disease

  Acute myocardial infarction

  This medicine should be used with extreme caution in patients suffering from a heart attack or heart failure. The uptake should be preceded by suitable clinical examinations to ensure safe and effective use.

  Hypotension

  This medicine should be used with extreme caution in patients who have low blood pressure. The risk of further lowering of blood pressure and associated adverse effects are significantly high.

  Glaucoma

  This medicine should be used with caution in patients suffering from glaucoma. It should be prescribed only after accessing the condition and making suitable adjustments in dosage.

• Interaction with Food

  Information not available.

• Ques : What is Isosorbide Dinitrate?

  Ans : Isosorbide Dinitrate is a medication that has Isosorbide Dinitrate as an active element present in it. Isosorbide Dinitrate is a vasodilator, it relaxes the heart blood vessels making it easier to pump blood.

• Ques : In what conditions can Isosorbide Dinitrate be used?

  Ans : Isosorbide Dinitrate is used to treat conditions such as severe chest pain, Congestive cardiac failure, Chf, relieve pain, and recurring angina attacks.

• Ques : Is Isosorbide Dinitrate safe to be consumed with other medicines?

  Ans : Isosorbide Dinitrate should not be taken with sildenafil (Viagra), as fatal side-effects may occur. It shouldn't be consumed if the patient is allergic to Isosorbide Dinitrate or nitroglycerine. Additionally, avoid taking it if you suffer from kidney disease, low blood pressure, severe anemia, and have early signs of heart failure.

• Ques : What are the Side Effects of Isosorbide Dinitrate?

  Ans : Isosorbide Dinitrate has many side effects such as Bluish discoloration of lips, fingernails, palm, or hands, Irregular heartbeat, Low blood pressure, Dizziness and fainting, Headache, Nausea or Vomiting, Chest pain and discomfort, Difficulty in swallowing, Hives and redness of the skin, burning or tingling sensation of hands and feet, Agitation and Anxiety, Sleeplessness, and Blood circulatory failure.

• Ques : How should Isosorbide Dinitrate be stored and disposed of?

  Ans : Isosorbide Dinitrate should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

• Ques : What are the directions to use Isosorbide Dinitrate?

  Ans : It should only be taken with a doctor’s prescription, Isosorbide Dinitrate can be taken with a glass of water. The dosage of this drug is different for different conditions: for angina, it is 30-120mg in daily divided dose, for heart failure it is 40-160mg in daily divided dose, however it should not be taken in more than daily 240mg in divided dose.

• Ques : Is it safe for pregnant and breastfeeding women to consume Isosorbide Dinitrate?

  Ans : Pregnant and breastfeeding women should not take Isosorbide Dinitrate without a doctor’s prescription.

• Ques : Should Isosorbide Dinitrate be taken in double dose if a dosage is missed?

  Ans : Do not take Isosorbide Dinitrate in double dose to make up for the missed one, take the medication as soon as you remember and take the next dosage at the right time.

• Ques : Should Isosorbide Dinitrate be consumed with alcohol?

  Ans : Consuming alcohol while on Isosorbide Dinitrate medication can cause side-effects such as flushing, increased heart rate, nausea, dizziness, chest pain, and low blood pressure. Therefore, it’s not advisable to consume alcohol with this drug.

• Ques : Is it safe to drive after taking a Isosorbide Dinitrate?

  Ans : Isosorbide Dinitrate doesn’t affect the driving capabilities of a person.

• Isosorbide dinitrate-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/isosorbide%20dinitrate

• Isosorbide dinitrate-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:

  https://go.drugbank.com/drugs/DB00883

• ISOSORBIDE DINITRATE capsule,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=ISOSORBIDE+DINITRATE