Letroz 2.5 Tablet

Letroz 2.5 Tablet is primarily used to treat Breast Cancer in Post-Menopausal Women. Sometimes, excess Estrogen in the body can stimulate Cancerous Cells to grow in the Breast. It is commonly used to treat estrogen-dependent Tumors.

Letroz 2.5 Tablet belongs to a group of drugs called Aromatase Inhibitors that prevents the conversion of Androgen to Estrogen in women. In Menopausal Women, the Ovaries do not produce Estrogen. Instead, the Body Fat, using a Protein called Aromatase, produce it. Letroz 2.5 Tablet inhibits the production of Estrogen and thus prevents the growth of a Tumor.

It also increases the thickness of the Endometrium and improves Follicular development in the Ovaries. This medication can also induce Ovulation in females if they are unable to do so naturally. Sometimes, this drug can be also prescribed to men with Breast Cancer. It is only prescribed if the biopsy shows Oestrogen Receptors within the cells.

Letroz 2.5 Tablet helps to reduce chances of Cancer returning to the same breast or metastasize. It can be taken as a tablet, once a day for 5 days, with or without food.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Breast Cancer

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Allergy

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Hot Flashes

• Bone Pain

• Chronic Musculoskeletal Pain

• Arthralgia

• Flushing

• Asthenia

• Edema (Swelling)

• Headache

• Dizziness

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• How long is the duration of effect?

  Since, Letrozole is an endocrine therapy, it needs to be taken for 5 years after the surgery to maintain its effect on the cancer.

• What is the onset of action?

  The drug therapy requires a minimum of 3-4 months to show any effect on the tumour.

• Are there any pregnancy warnings?

  Letrozole is used in post-menopausal women only. It is contraindicated in pregnant women.

• Is it habit forming?

  It is not habit-forming.

• Are there any breast-feeding warnings?

  This drug is incompatible with breastfeeding women. There is an increased risk of foetal malformation.

• Is It safe with alcohol?

  It is unsafe to drink alcohol while undergoing this hormone therapy for increases chances of headaches and nausea.

• Is it safe to drive while on this medicine?

  Drive with caution if you are suffering from any of the side-effects.

• Does this affect kidney function?

  There has been no kidney impairment reported due to this hormone therapy.

• Does this affect liver function?

  It increases the enzyme level in the liver and interferes with the normal functioning of the liver.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Are there any missed dose instructions?

  If you miss a dose, you do not need to take it the next day since the hormone level in your system will be high enough from the previous day.

• Are there any overdose instructions?

  Contact emergency services immediately if you overdose. Overdosing will enhance the severity of the side-effects.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

This medication falls under the class of non-steroidal aromatase inhibitors. It competitively binds to the haem of the cytochrome P450 subunit of the aromatase enzyme and inhibits the biosynthesis of estrogen in all the tissues. Thus inhibits the growth of breast cancer.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Medicine

  Letroz 2.5 Tablet interacts with other estrogen-containing drugs like hormone replacement therapy (HRT) and other drugs like ethinylestradiol, tamoxifen, cholera vaccine and eluxadoline.

• Interaction with Food

  Information not available.

• Interaction with Disease

  Letroz 2.5 Tablet is dangerous to be used in patients with existing liver disease. The drug increases the enzyme level in the liver.

• Ques : Why have I been prescribed Letroz 2.5 Tablet?

  Ans : This drug is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women. Sometimes, it is also used to treat infertility caused due to an ovulation.

• Ques : How does Letroz 2.5 Tablet work?

  Ans : This drug is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for the production of estrogen.

• Ques : For how long should I take Letroz 2.5 Tablet?

  Ans : It is advised to consult the doctor and consume it as prescribed by your doctor.

• Ques : If I am taking irbesartan to control my blood pressure, can I take Letroz 2.5 Tablet too?

  Ans : Yes, you can take irbesartan and Letroz 2.5 Tablet together.

• Ques : Does Letroz 2.5 Tablet affect vision?

  Ans : Although it is very uncommon, this drug may cause cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.

• Ques : What are the serious side effects of Letroz 2.5 Tablet?

  Ans : Side effects include stroke, angina, heart attack, blood clotting, cataract, osteoporosis and severe skin reactions.

• Ques : Does Letroz 2.5 Tablet cause bone loss?

  Ans : It may cause thinning or wasting of your bones (osteoporosis), which is due to the decrease in estrogen levels in your body. Your doctor may decide to measure your bone density (a way of monitoring for osteoporosis) before, during, and after treatment.

• Letrozole-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/letrozole

• Letrozole-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:

  https://go.drugbank.com/drugs/DB01006

• LETROZOLE tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=LETROZOLE