Librium 10mg Tablet

Librium 10mg Tablet is a benzodiazepine and used for the management of anxiety disorders or for the short-term relief of symptoms of anxiety; withdrawal symptoms of acute alcoholism; and preoperative apprehension and anxiety. It is a sedative and a hypnotic medication. This medication functions by slowing down the movement of chemicals in the brain.

On using this drug you may experience side effects such as dizziness, drowsiness, constipation, angioedema, increased appetite, hallucinations, psychotic disorder, emotional disturbances, etc.

Before using this drug inform your doctor if you have or are:

• Pregnant or breastfeeding.
• Taking any prescription or non-prescription drugs.
• Any allergies to any medicines, foods or substances.
• A history of glaucoma.
• Liver/ lung/ muscle/ drug abuse problems or you smoke.

The dosage for this drug should be determined by your doctor based on the patient specifications. The usual dosage for anxiety disorders and sedation is about 5-10 mg, taken thrice or four times a day. For alcohol withdrawal dosage is 50-100 mg, taken orally per day.

Take exactly as directed (do not increase dose or frequency); may cause physical and/or psychological dependence. Do not use excessive alcohol or other prescription or OTC medications (especially pain medications, sedatives, antihistamines, or hypnotics) without consulting prescriber.Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake).

You may experience drowsiness, lightheadedness, impaired coordination, dizziness, or blurred vision (use caution when driving or engaging in tasks requiring alertness until response to drug is known); or dry mouth (small frequent meals, frequent mouth care, chewing gum, or sucking lozenges may help); constipation (increased exercise, fluids, or dietary fruit and fiber may help); or altered sexual drive or ability (reversible).

Report persistent CNS effects (eg, euphoria, confusion, increased sedation, depression); chest pain, palpitations, or rapid heartbeat; muscle cramping, weakness, tremors, rigidity, or altered gait; or worsening of condition.

Treatment for benzodiazepine overdose is supportive; rarely is mechanical ventilation required; flumazenil has been shown to selectively block the binding of benzodiazepines to CNS receptors, resulting in a reversal of benzodiazepine-induced CNS depression. Respiratory depression may not be reversed.

Symptoms of overdose include hypotension, respiratory depression, coma, hypothermia, cardiac arrhythmias.

Treatment for benzodiazepine overdose is supportive; rarely is mechanical ventilation required; flumazenil has been shown to selectively block the binding of benzodiazepines to CNS receptors, resulting in a reversal of benzodiazepine-induced CNS depression. Respiratory depression may not be reversed.

• Anxiety Disorder

• Allergy

• Narrow Angle Glaucoma

• Pregnancy

• Drowsiness

• Fatigue

• Ataxia

• Light Headedness

• Memory Impairment

• Irritability

• Rash

• Decreased Libido

• Hypotension

• Confusion

• Dizziness

• Akathisia

• Increased Libido

• Dermatitis

• Sexual Dysfunction

• Tremor

• Muscle Cramps

• Tinnitus

• Nasal Congestion

• Is It safe with alcohol?

  The tablet may cause excessive drowsiness and calmness with alcohol.

• Are there any pregnancy warnings?

  This medicine is extremely unsafe to be used during pregnancy.

• Are there any breast-feeding warnings?

  Please consult your doctor before using this medicine if you are breastfeeding.

• Is it safe to drive while on this medicine?

  Caution is advised when driving or operating machinery.

• Does this affect kidney function?

  Caution should be exercised with impaired Renal function. Dosing adjustment in renal impairment: Clcr <10 mL/minute: Administer 50% of dose. Hemodialysis: Not dialyzable (0% to 5%).

• Does this affect liver function?

  Avoid using Librium 10mg Tablet. Please consult a doctor before consuming the drug.

• How long is the duration of effect?

  This medicine will remain active for about 48 hours to 1 week, depending on the dose taken.

• What is the onset of action?

  The effect of this medicine will be initiated within 2 hours after its ingestion.

• Are there any missed dose instructions?

  Take the missed dose as soon as possible.

• Are there any overdose instructions?

  Consult a doctor in case of overdose.

This medication binds to stereospecific benzodiazepine receptors on the postsynaptic GABA neuron at several sites within the central nervous system, including the limbic system, reticular formation. Enhancement of the inhibitory effect of GABA on neuronal excitability results by increased neuronal membrane permeability to chloride ions. This shift in chloride ions results in hyperpolarization (a less excitable state) and stabilization.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Lab Test

  This medicine alters the level of HDL, and triglycerides (S) in the patient taking it.

• Interaction with Medicine

  Increased toxicity: Cimetidine, ciprofloxacin, clarithromycin, clozapine, CNS depressants, diltiazem, disulfiram, digoxin, erythromycin, ethanol, fluconazole, fluoxetine, fluvoxamine, grapefruit juice, isoniazid, itraconazole, ketoconazole, labetalol, levodopa, loxapine, metoprolol, metronidazole, miconazole, nefazodone, omeprazole, phenytoin, rifabutin, rifampin, troleandomycin, valproic acid, verapamil may increase the serum level and/or toxicity of alprazolam; monitor for altered benzodiazepine response.

• Interaction with Disease

  • Active metabolites with extended half-lives may lead to delayed accumulation and adverse effects. Use with caution in elderly or debilitated patients, pediatric patients, patients with hepatic disease (including alcoholics) or renal impairment. Use with caution in patients with respiratory disease or impaired gag reflex. Use with caution in patients with porphyria.
  • Causes CNS depression (dose-related) resulting in sedation, dizziness, confusion, or ataxia which may impair physical and mental capabilities. Patients must be cautioned about performing tasks which require mental alertness (ie, operating machinery or driving). Use with caution in patients receiving other CNS depressants or psychoactive agents (lithium, phenothiazines). Effects with other sedative drugs or ethanol may be potentiated. Benzodiazepines have been associated with falls and traumatic injury and should be used with extreme caution in patients who are at risk of these events (especially the elderly).
  • Use caution in patients with depression, particularly if suicidal risk may be present. Use with caution in patients with a history of drug dependence. Benzodiazepines have been associated with dependence and acute withdrawal symptoms on discontinuation or reduction in dose. Acute withdrawal, including seizures, may be precipitated in patients after administration of flumazenil to patients receiving long-term benzodiazepine therapy.
  • Benzodiazepines have been associated with anterograde amnesia. Paradoxical reactions, including hyperactive or aggressive behavior have been reported with benzodiazepines, particularly in adolescent/pediatric or psychiatric patients. Does not have analgesic, antidepressant, or antipsychotic properties.

• Ques : What is Librium 10mg Tablet?

  Ans : Librium tablet is a medication which has Chlordiazepoxide as an active ingredient present in it. This medicine performs its action by calming the nerves in the brain.

• Ques : What are the uses of Librium 10mg Tablet?

  Ans : Librium 10mg is used for the treatment and prevention from conditions and symptoms of diseases like severe anxiety and flushing.

• Ques : What are the Side Effects of Librium 10mg Tablet?

  Ans : Dizziness, restlessness and skin rashes, appetite loss, menstrual disorders are possible side effects.

• Ques : What are the instructions for storage and disposal Librium 10mg Tablet?

  Ans : Librium tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Ques : Should I use Librium 10mg Tablet empty stomach, before food or after food?

  Ans : You are free to take this medication either before or after having food. it will not create any hindrance in medication’s action, neither it will affect its effectiveness.

• Ques : How long do I need to use Librium 10mg Tablet before I see improvement of my conditions?

  Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 2 days, before noticing an improvement in the condition.

• Ques : Is there any food or drink I need to avoid?

  Ans : If you are under the usage of this medication, it is recommended to avoid caffeine.

• Ques : Will Librium 10mg Tablet be more effective if taken in more than the recommended dose?

  Ans : Excess of usage of this medication can trigger side effects.