Lupibrin 1% Eye Drop

Lupibrin 1% Eye Drop is commonly available in the form of a solution, to be administered as eye drops. It is mainly used to reduce elevated levels of pressure in the eye, especially in patients suffering from ocular hypertension and / or open-angle glaucoma. This drug is an inhibitor of carbonic anhydrase, which causes an increased amount of fluid to be present in the eye. Hence, this medicine works by reducing the amount of fluid present in the eye, which further leads to a reduction in the ocular pressure.

Consult your doctor if you wear contact lenses. The chances of this medicine being absorbed into your bloodstream are very low, and hence negligible, so the probability of any drug interactions with this medicine is very low. You are strongly recommended to avoid using these eye drops if you have had an allergic reaction to any of the ingredients in this medicine. You are advised to avoid using these drops if you are pregnant or breastfeeding. The drops may cause a brief stinging or burning sensation in the eyes, which is quite normal; but if this persists, consult with your medical practitioner. This medication may cause blurred vision; do not drive in such cases.

• Glaucoma

• Stinging In The Eyes

• Blurred Vision

• Burning Eyes

• Is It safe with alcohol?

  No interaction found

• Are there any pregnancy warnings?

  Lupibrin 1% Eye Drop may be unsafe to use during pregnancy.
  Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is it safe to drive while on this medicine?

  Patient should wait until the vision clears before driving or using machines.
  Caution is advised when driving or operating machinery.

• Does this affect kidney function?

  Caution to be advised in patients with impaired renal function.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

Below is the list of medicines, which have the same composition, strength and form as Lupibrin 1% Eye Drop , and hence can be used as its substitute.

• Brinolar 1% W/V Eye Drop

  Sun Pharmaceutical Industries Ltd

Lupibrin 1% Eye Drop is a highly specific, reversible, non competitive inhibitor of Carbonic Anhydrase II involved in aqueous humor secretion. CA inhibition in the eyes slows down bicarbonate formation and reduces transport of sodium and fluids, which reduces aqueous humor secretion and intraocular pressure.

• Brinzolamide- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 12 December 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/brinzolamide

• Brinzolamide- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 12 December 2019]. Available from:

  https://www.drugbank.ca/drugs/DB01194

• Azopt eye drops, suspension- EMC [Internet] medicines.org.uk. 2018 [Cited 12 December 2019]. Available from:

  https://www.medicines.org.uk/emc/product/3819/smpc