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Overview

Maclitaxel 260 MG Injection

Manufacturer :  Macleods Pharmaceuticals Pvt.Ltd
Medicine Composition :  Paclitaxel
Prescription vs OTC : Prescription by Doctor required

About Maclitaxel 260 MG Injection

Maclitaxel 260 MG Injection is an anticancer medicine, used in chemotherapy to treat a number of cancers. Primarily it is used in the treatment of breast cancer and ovarian cancer. It is sold under the trade name of Taxol. Maclitaxel 260 MG Injection is categorized as a plant alkaloid, a taxane and a antimicrotublue agent. Maclitaxel 260 MG Injection is injected into the body by injection or infusion.

Maclitaxel 260 MG Injection is a type of irritant that may cause an inflammation of your vein through which it is being given. Other side effects or reactions that you may experience on taking Maclitaxel 260 MG Injection are nausea, vomiting tendency, hair loss, diarrhea, hypersensitivity, mucositis, skin rash, flushing, blurred vision, numbness, dizziness, fever, paleness, difficulty in breathing, cough, sweating, slow or irregular heartbeat and chest pain. In certain adverse cases, it may cause major arthralgia, myalgia. It is advised that you seek medical attention if you are afflicted with any of these side effects.

Before taking Maclitaxel 260 MG Injection discuss with your doctor if you have any of the conditions mentioned below:

  • If you are taking any prescriptive or over the counter drugs, herbal medications or dietary supplements.
  • If you are planning to take any immunization, vaccination or radiation treatment anytime soon.
  • If you are pregnant or are planning to become pregnant or are nursing a baby.
  • If you have any allergies, bacterial or viral infections.
  • If you are under 18 years of age.
  • If you have heart, liver, kidney or bone marrow disorders.

Do not get pregnant while under Maclitaxel 260 MG Injection treatment. Use contraception for both men and women. Should you become pregnant, notify your doctor. The dosage is determined by your doctor according to your individual specifications and condition. The usual dose for treatment in ovarian and breast cancer is of two types; one is giving about 175 mg for three hours every three weeks followed by a Cisplatin therapy. And the second one is giving 135 mg for 24 hours every three weeks followed by the same cisplatin therapy.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the uses of Maclitaxel 260 MG Injection

    • Ovarian Cancer

      Maclitaxel 260 MG Injection is used in the treatment of cancer that affects the female reproductive system.

    • Breast Cancer

      Maclitaxel 260 MG Injection is used in the treatment of breast cancer.

    • Non-Small Cell Lung Cancer

      Maclitaxel 260 MG Injection is used in the treatment of Non-Small Cell Lung Cancer which is a type of cancer that affects the lungs.

    • Kaposi's Sarcoma

      Maclitaxel 260 MG Injection is used in the treatment of Kaposi's Sarcoma which is a type of cancer that develops under the skin in the lining of mouth, nose, and throat.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the contraindications of Maclitaxel 260 MG Injection ?

    • Allergy

      Not recommended in the patients with known allergy to Maclitaxel 260 MG Injection.

    • Neutrophils Count

      Not recommended in the patients with neutrophils count less than 1,500 cells/mm3

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the side effects of Maclitaxel 260 MG Injection ?

    • Neutropenia

    • Difficulty In Swallowing

    • Dizziness

    • Fever

    • Pale Skin

    • Allergic Skin Reaction

    • Mouth Ulcers

    • Difficulty In Breathing

    • Chest Discomfort

    • Swelling And Redness At The Injection Site

    • Diarrhoea

    • Hair Loss Or Thinning Of The Hair

    • Nausea Or Vomiting

    • Joint Pain

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    Key highlights of Maclitaxel 260 MG Injection

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 27 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed in less than an hour.

    • Are there any pregnancy warnings?

      This medicine is not recommended for pregnant women.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medicine is not recommended in breastfeeding women.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the substitutes for Maclitaxel 260 MG Injection ?

    Below is the list of medicines, which have the same composition, strength and form as Maclitaxel 260 MG Injection , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    Where is the Maclitaxel 260 MG Injection approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    How does this medication work?

    This medicine belongs to the class antimicrotubule agent. It stabilizes the microtubules by precluding the depolymerization. This results in the hindrance of the normal reorganization dynamics of the microtubule network. This reorganisation is essential for vital interphase and cellular functions like mitotic.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

      What are the interactions of Maclitaxel 260 MG Injection ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Medicine

        Clozapine

        These medicines may further lower the white blood cell count if received together. Any symptoms of fever, diarrhea, sore throat, chills should be informed to the doctor. Close monitoring of blood cell count is necessary. An alternate medicine should be considered based on the clinical condition.

        Diltiazem

        Diltiazem may increase the concentration of Maclitaxel 260 MG Injection and may cause serious effects like low white blood cells count, hair loss, nausea, and vomiting. Inform the doctor if you are receiving any antihypertensives before initiation of the treatment. An alternate medicine should be considered based on the clinical condition.

        Atorvastatin

        These medicines may increase the risk of nerve damage if given together. Any symptoms of numbness, tingling or burning sensation in feet, hands should be informed to the doctor. An alternate medicine should be considered based on the clinical condition.

        Live vaccines

        You may be at the risk of developing infections if these medicines are taken together. Inform the doctor if you had received either of these medicines. Your doctor may postpone therapy based on the condition.
      • Interaction with Disease

        Cardiac Conduction Abnormalities

        This medicine is known to cause serious heart conduction abnormalities. Inform the doctor if you have any heart diseases. Close monitoring of low blood pressure and decreased heartbeat is necessary.
      • Interaction with Food

        Food

        Information not available.

      References

      • Paclitaxelt-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/paclitaxel

      • Paclitaxel-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:

        https://go.drugbank.com/drugs/DB01229

      • PACLITAXEL injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=PACLITAXEL

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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