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Overview

Medabon 200 MG Tablet

Manufacturer :  Glenmark Pharmaceuticals Europe Ltd
Medicine Composition :  Mifepristone, Misoprostol
Prescription vs OTC : Prescription by Doctor not required

About Medabon 200 MG Tablet

A medical termination pack or Medabon 200 MG Tablet consists of two medicines Mifepristone and Misoprostol that are used to medically terminate the pregnancy. The kit contains 5 tablets. One tablet of Mifepristone and four tablets of Misoprostol.

It is medically prescribed if you are within 63 days of gestation. Doctors do not opt for this process if you are over 10 weeks pregnant. Mifepristone is a synthetic steroid taken orally with water. It interferes with the Progesterone Secretion that terminates the Pregnancy.

Misoprostol is a Synthetic Prostaglandin that causes the cervix to soften, contract the Uterus and allows the emptying of the uterine contents. It is administered vaginally or orally depending on the patient’s condition.

Misoprostol may be self-administered or administered under a gynaecologist’s supervision so that the patient has access to the health facilities, if necessary. In case of an intrauterine pregnancy, termination by surgery is recommended.

The dosage is 1 tablet of Mifepristone, followed by 4 tablets of Misoprostol after 1-3 days. If abortion fails to occur after the administration of Misoprostol, the second dose of Misoprostol (2 tablets) is administered. In case of an intrauterine pregnancy, termination by surgery is recommended.

    What are the uses of Medabon 200 MG Tablet

    What are the contraindications of Medabon 200 MG Tablet ?

    • Allergy

    • Ectopic Pregnancy

    • Current use of intra-uterine device

    • Chronic Adrenal Failure

    • Corticosteroids

    • Unexplained Vaginal Bleeding

    • Other Bleeding Disorders

    • Porphyria

    What are the side effects of Medabon 200 MG Tablet ?

    • Infections

    • Uterine Cramping

    • Headache

    • Dizziness

    • Pain In The Legs

    • Decreased Appetite

    • Sleeplessness

    • Difficulty In Swallowing

    Key highlights of Medabon 200 MG Tablet

    • How long is the duration of effect?

      The effect of this medication lasts for an average duration of 7-10 days.

    • What is the onset of action?

      This medication is rapidly absorbed into the bloodstream upon oral administration and reaches the peak levels within 1-2 hours.

    • Are there any pregnancy warnings?

      This medication is adequate for medical termination of 63-70 days old intrauterine pregnancy, while a failed attempt of pregnancy termination could result in severe complications. With an elevated cortisol level, this medicine is not recommended to pregnant women. However, it is used to control elevated blood sugar levels.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      The use of this medication should be avoided by women who are breastfeeding. However, if it becomes necessary to use this medicine then breastfeeding should be discontinued. Consult your doctor regarding the potential benefits and risks involved before taking this medicine.

    What are the substitutes for Medabon 200 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Medabon 200 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Missed Dose instructions

      Missed dose should be taken as soon as possible. It is recommended to skip your missed dose, if it is the time for your next scheduled dose.

    • Are there any overdose instructions?

      Contact your doctor and seek immediate help if an overdose with this medication is suspected.

    How does this medication work?

    This kit blocks the effect of progesterone by competitively binding to the specific receptors and sensitizing the inner linings of the uterus inducing bleeding and contractions. It also blocks the effect of cortisol at the specific receptors and reducing the effect caused by an excess of this hormone.

    Misoprostol taken intravaginally behaves as a prostaglandin E1 analogue and reduces the amount of acid produced in the stomach. It further protects the stomach walls by increasing the production of bicarbonates and mucus. It can cause the smooth muscles of the uterus to contract and the cervix to relax.

      What are the interactions of Medabon 200 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        This medication interacts with Dexamethasone, Erythromycin, Hydrocortisone, Ketoconazole, Simvastatin, Pimozide, Warfarin, and Ergotamine.

      FAQs about Medabon 200 MG Tablet

      • Ques : What is Medabon 200 MG Tablet?

        Ans : This kit has Mifepristone and Misoprostol as active elements present. It is primarily prescribed as a pregnancy termination kit.

      • Ques : What are the Side Effects of Medabon 200 MG Tablet?

        Ans : This kit has some commonly reported side effects. Here are some side effects of this kit which are as follows: diarrhoea, stomach pain, vaginal bleeding, pelvic pain and cramping, shortness of breath, allergic skin reaction, swelling of face, etc.

      • Ques : What are the instructions for storage and disposal Medabon 200 MG Tablet?

        Ans : Store this kit in a cool dry place and keep it in the original pack or container until it is time to take them. Store this medication out of sight and reach of children. Unused medicines should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

      • Ques : How long do I need to use Medabon 200 MG Tablet before I see improvement of my conditions?

        Ans : This kit takes 1 or 2 days before you see an improvement in your health conditions. It would be ideal if you note, it doesn't mean you will begin to notice such health improvement in a similar time span as different patients.

      • Ques : What are the contraindications to Medabon 200 MG Tablet?

        Ans : In addition, this kit should not be used if you have the following conditions such as hemorrhagic disorder, hypersensitivity, inherited porphyrias, pregnancy and lactation, suspected ectopic pregnancy, etc.

      • Ques : Is Medabon 200 MG Tablet safe to use when pregnant?

        Ans : This medication is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

      • Ques : Will Medabon 200 MG Tablet be more effective if taken in more than the recommended dose?

        Ans : No, taking higher than the recommended dose of this kit can lead to increased chances of side effects such as abdominal pain, indigestion, back pain, excessive vaginal bleeding, emesis, diarrhoea, vomiting, heavy bleeding, anxiety, etc.

      References

      • Mifepristone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/mifepristone

      • Mifepristone- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 1 February 2020]. Available from:

        https://www.drugbank.ca/drugs/DB00834

      • Misoprostol- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/misoprostol

      • Misoprostol- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 1 February 2020]. Available from:

        https://www.drugbank.ca/drugs/DB00929

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Content Details
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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