Methyl Prednisolone

Methyl Prednisolone is primarily as an anti-inflammatory or immunosuppressant agent in the treatment of a variety of diseases including those of hematologic, allergic, inflammatory, neoplastic, and autoimmune origin. It is also used in the prevention and treatment of graft-versus-host disease following allogeneic bone marrow transplantation.

Methyl Prednisolone is a steroid, which prevents the release of certain chemicals in the body that result in inflammation. The drug is quite effective in the treatment of a number of inflammatory health problems such as gland disorders, lupus, arthritis, psoriasis as well as ulcerative colitis.

It also treats various other inflammatory conditions of the lungs, skin, eyes, blood cells, stomach and nervous system of the body. Before you start the medicine the doctor needs to ensure:

• If the medicine is safe for the patient
• If you have allergies, overall fitness, and existing health problems
• If you have problems like hypertension, heart disease, kidney or liver issues, tuberculosis, pinworms, thyroid disorders, mental illness, epilepsy or epilepsy

The dosage of the medicine for adults may vary from 4mg to 48mg daily. In the case of children, the dosage is decided to depend upon the health of the patient and the condition that is being treated.

Certain precautions should also be taken to prevent side effects from aggravating. For instance, avoid grapefruit juice consumption. it is also advised that ‘live’ vaccines should not be taken when on this drug. Patients taking this medication can easily catch infections. Thus they should also avoid interacting with sick family members or friends.

Methyl Prednisolone must be used with caution in patients with hyperthyroidism, cirrhosis, nonspecific ulcerative colitis, hypertension, osteoporosis, thromboembolic tendencies, CHF, convulsive disorders, myasthenia gravis, thrombophlebitis, peptic ulcer, diabetes.

Because of the risk of adverse effects of Methyl Prednisolone, systemic corticosteroids should be used cautiously in the elderly, in the smallest possible dose, and for the shortest possible time.

Arrhythmias and cardiovascular collapse are possible with rapid intravenous infusion of high dose methylprednisolone. Symptoms of overdose include cushingoid appearance (systemic), muscle weakness (systemic), osteoporosis (systemic) all with long-term use only.

When consumed in excessive quantities for prolonged periods, systemic hypercorticism and adrenal suppression may occur; in those cases, discontinuation and withdrawal of the corticosteroid should be done judiciously.

Maintain adequate nutritional intake; consult prescriber for possibility of special dietary instructions. If diabetic, monitor serum glucose closely and notify prescriber of any changes; this medication can alter hypoglycemic requirements.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Immunosuppression

• Asthma

• Eye Disorder

• Skin Disorders

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Allergy

• Fungal Infections

• Idiopathic Thrombocytopenic Purpura

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Insomnia

• Nervousness

• Increased Appetite

• Indigestion

• Hirsutism

• Diabetes Mellitus

• Hyperlipidemia

• Arthralgia

• Glaucoma

• Infections

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• How long is the duration of effect?

  The effect of this medicine lasts for a duration of 30-36 hours after an oral dose and 1-4 weeks after an intramuscular injection.

• What is the onset of action?

  The peak effect of this medicine is observed within 30 minutes of an intravenous injection.

• Are there any pregnancy warnings?

  This medicine is recommended for pregnant women only if clearly needed and if no other safer alternative is available.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is known to be excreted through breast milk in small amounts.

• Is It safe with alcohol?

  Consumption of alcohol must be avoided when you were taking Methyl Prednisolone.

• Is it safe to drive while on this medicine?

  This medicine might affect the consciousness of the patient, thus driving must be avoided.

• Does this affect kidney function?

  This medicine is found to be safe in patient with kidney disease. Adjustment of dose is not needed.

• Does this affect liver function?

  Limited information is available on the use of this medicine in patient with liver disease. kindly consult your doctor before taking this.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Missed Dose instructions

  The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Below is the list of medicines, which contains Methyl Prednisolone as ingredient

• Rednisol 4 MG Tablet

  Leeford Healthcare

• Predace 4 MG Tablet

  Micro Labs Ltd

• Macpred 4 MG Tablet

  Macleods Pharmaceuticals Pvt.Ltd

• Zempred 8 MG Tablet

  Sun Pharma Laboratories Ltd

• Predmet 16 MG Tablet

  Sun Pharma Laboratories Ltd

• Mepresso-T 4 MG Tablet

  Intas Pharmaceuticals Ltd

• Sol U Pred 1 GM Injection

  United Biotech (P) Ltd

• Depotex 4 MG Tablet

  Zydus Cadila

• Grafmet 500 MG Injection

  Panacea Biotec Ltd

• Prendicare 8 MG Tablet

  Menarini India

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

This medicine belongs to Glucocorticoids class of drugs. It works by binding to the receptor and inhibits the release of inflammatory substances thus helps in the treatment of inflammation or allergic disorders.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Methyl Prednisolone interferes with skin tests.

• Interaction with Medicine

  • CYP3A enzyme inducer.
  • Phenytoin, phenobarbital, rifampin increase clearance of methylprednisolone.
  • Potassium depleting diuretics enhance potassium depletion.
  • Increased toxicity:
    • Skin test antigens, immunizations decrease response and increase potential infections
    • Methylprednisolone may increase circulating glucose levels and may need adjustments of insulin or oral hypoglycemics

• Interaction with Disease

  Gastrointestinal Bleeding

  This medication is used with caution in patients with gastrointestinal diseases. The risk of bleeding is more when taken for a long duration of time. Dose adjustments are to be made based on the clinical condition.

  Diabetes

  This medicine is used with caution in the patients with diabetes as it increases the blood glucose levels. Regular monitoring of blood glucose levels is necessary. A suitable antidiabetic agent is prescribed based on the clinical condition.

  Others

  Use with caution in patients with hyperthyroidism, cirrhosis, nonspecific ulcerative colitis, hypertension, osteoporosis, thromboembolic tendencies, CHF, convulsive disorders, myasthenia gravis, thrombophlebitis, peptic ulcer.

• Interaction with Food

  • Consumption of grapefruit juice is not recommended when you are taking Methyl Prednisolone. Inform the doctor if you experience any undesired effects.
  • Should be taken after meals or with food or milk; limit caffeine; need a diet rich in pyridoxine, vitamin C, vitamin D, folate, calcium, phosphorus, and protein.

• Ques : What is Methyl Prednisolone?

  Ans : This medication is a steroid, which prevents the release of certain chemicals in the body that result in inflammation.

• Ques : How long do I need to use Methyl Prednisolone before I see improvement in my condition?

  Ans : It is advisable to take this drug for the duration prescribed by your doctor. Do not stop the treatment suddenly or take for a longer period than recommended by your doctor.

• Ques : At what frequency do I need to use Methyl Prednisolone?

  Ans : This medication should be taken in the dosage as prescribed by the doctor.

• Ques : Should I use Methyl Prednisolone empty stomach, before food or after food?

  Ans : This medication should be taken after food in a prescribed dosage.

• Ques : What are the instructions for the storage and disposal of Methyl Prednisolone?

  Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

• Ques : Does Methyl Prednisolone contain penicillin?

  Ans : No, it does not contain penicillin. This drug belongs to a group of medicines called steroids.

• Ques : Does Methyl Prednisolone expire?

  Ans : Yes, it does expire. All the medicines come with an expiry date mentioned on the pack. It is advised for you to check the expiry date mentioned on the medicine before use.

• Ques : Is Methyl Prednisolone a pain-killer?

  Ans : No, Methyl Prednisolone is not a pain-killer.

• Ques : Is Methyl Prednisolone safe?

  Ans : This drug is completely safe to use if taken as per the prescription of the doctor.

• Ques : Is Methyl Prednisolone an immunosuppressant?

  Ans : This drug has immunosuppressant properties which means it suppresses the body’s immune system. Hence, it is used for the treatment of a number of inflammatory and auto-immune conditions.

• Ques : Is Methyl Prednisolone a glucocorticoid?

  Ans : Yes, it is a glucocorticoid. It belongs to a group of medicines called steroids (corticosteroids).

• Ques : Can I take Methyl Prednisolonen with antibiotics?

  Ans : Certain antibiotics may increase the metabolism of this medication and hence decrease its effects.

• Ques : Can I take Methyl Prednisolone with paracetamol?

  Ans : Yes, this drug can be taken with paracetamol.

• Methylprednisolone-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/methylprednisolone

• Methylprednisolone-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 1 June 2022].Available from:

  https://go.drugbank.com/drugs/DB00959

• METHYLPREDNISOLONE Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=METHYLPREDNISOLONE