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Overview

Metosartan 25 Tablet

Manufacturer :  Sun Pharmaceutical Industries Ltd
Medicine Composition :  Telmisartan, Metoprolol
Prescription vs OTC : Prescription by Doctor not required

About Metosartan 25 Tablet

Metosartan 25 Tablet is primarily prescribe for the treatment of high blood pressure and angina pectoris. It also helps in preventing of myocardial infarction, atrial fibrillation, flutter, symptomatic treatment of hypertrophic subaortic stenosis. Metosartan 25 Tablet helps maintain optimal blood pressure levels in a person’s body. In patients who suffer from hypertension, it can lower the blood pressure.

Metosartan 25 Tablet works by widening and dilating the blood vessels, which relaxes them. It also helps the kidney flush out excess salt and water, thus reducing the blood pressure. Therefore, Metosartan Tablet is highly effective in treating hypertension.

The regular recommended dosage of Metosartan 25 Tablet is a 50 mg tablet, taken once a day. The doctor might increase the dosage to 100 mg, if you suffer from serious conditions of the heart. It is important to continue taking this medication according to the doctor’s prescription, until you have completed the course. You should not skip out on a dose, and if you do forget, do not take an extra dose to make up for it.

Pregnant women or women who are trying to get pregnant should avoid consuming this drug, since it can cause harm the baby's development. It might not be suitable for everyone, since consuming this drug can lead to complications for patients affected by disorders such as:

If you suffer from these conditions, you should inform your doctor, before taking this medicine.

The common side effects of Metosartan 25 Tablet are diarrhea, headache, vomiting, nausea, chest congestion, fatigue, body and muscle aches. These side effects are minor and usually disappear within a week or two. If they continue for a prolonged period, consult your doctor.

The major side effects of Metosartan Tablet include dizziness, nausea, swelling of the hands, ankles, or feet and sudden weight gain. If you have an allergy to this medicine, you will experience symptoms such as swelling of the tongue, throat or face, rashes, itchiness and difficulty breathing.

If you have an allergic reaction to Metosartan 25 Tablet, it is advisable to discontinue the usage of this medicine and contact your doctor immediately. This drug interacts with other medications as well as alcohol, in a negative way. Therefore, make sure you inform your doctor of all the other medicines you are taking, before beginning a course of Metosartan 25 Tablet.

    What are the uses of Metosartan 25 Tablet

    What are the contraindications of Metosartan 25 Tablet ?

    What are the side effects of Metosartan 25 Tablet ?

    Key highlights of Metosartan 25 Tablet

    • How long is the duration of effect?

      The effect of this medication lasts for a duration of 24 hours approximately.

    • What is the onset of action?

      The peak effect of this medicine can be observed within 1 to 2 hours of adminstration.

    • Are there any pregnancy warnings?

      This medicine is not recommended for pregnant women.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      This medicine is not recommended for breastfeeding women.

    • Is It safe with alcohol?

      This medicine is unsafe to consume alcohol while taking this medicine.

    • Is it safe to drive while on this medicine?

      This medicine affect the conscious of the patient, thus affecting the patients ability to drive.

    • Does this affect kidney function?

      This medicine is find to be safe if prescribed in patients with kidney disease. Adjustment of dose is not recommended.

    • Does this affect liver function?

      Caution must be taken in patient with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

    What are the substitutes for Metosartan 25 Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Metosartan 25 Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    How does this medication work?

    This displaces angiotensin II with very high affinity from its binding site at the AT1 receptor subtype. It is responsible for the known actions of angiotensin II. The other active constituent of the composition Metoprolol blocks beta receptors sites in the heart, blood vessels, and lungs. This results in inhibition of epinephrine resulting in relaxed blood vessels. Thus pressure is lowered and blood flow to the heart is improved.

      What are the interactions of Metosartan 25 Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        • Clonidine: Hypertensive crisis after or during withdrawal of either agent.
        • Drugs which slow AV conduction (digoxin): effects may be additive with beta-blockers.
        • Fluoxetine may inhibit the metabolism of Metosartan 25 Tablet resulting in cardiac toxicity.
        • Glucagon: Metosartan 25 Tablet may blunt the hyperglycemic action of glucagon.
        • Hydralazine may enhance the bioavailability of Metosartan 25 Tablet.
        • Insulin and oral hypoglycemics: Metosartan 25 Tablet may mask tachycardia from hypoglycemia.
        • Metosartan 25 Tablet reduces antipyrine's clearance by 18%.
        • NSAIDs (ibuprofen, indomethacin, naproxen, piroxicam) may reduce the antihypertensive effects of beta-blockers.
        • Oral contraceptives may increase the AUC and Cmax of Metosartan 25 Tablet.
        • Salicylates may reduce the antihypertensive effects of beta-blockers.
        • Sulfonylureas: Beta-blockers may alter response to hypoglycemic agents.
        • Verapamil or diltiazem may have synergistic or additive pharmacological effects when taken concurrently with beta-blockers; avoid concurrent I.V. use.
      • Interaction with Disease

        Avoid abrupt discontinuation in patients with a history of CAD; slowly wean while monitoring for signs and symptoms of ischemia. Use caution in patients with PVD (can aggravate arterial insufficiency). Use cautiously in diabetics because it can mask prominent hypoglycemic symptoms. Can mask signs of thyrotoxicosis. Can cause fetal harm when administered in pregnancy. Use cautiously in the hepatically impaired. Use care with anesthetic agents which decrease myocardial function.

      FAQs about Metosartan 25 Tablet

      • Ques : What is Metosartan 25 tablet?

        Ans : This is a medication which has Metoprolol and Telmisartan as active elements present. It performs its action by calming blood vessels thus reducing blood pressure and by reducing infarct size, obstructing the action of a substance responsible for narrowing the blood vessels.

      • Ques : What are the uses of Metosartan 25 tablet?

        Ans : This is a medication, which is used for the treatment and prevention from conditions such as High blood pressure, Myocardial infarction, Cardiac arrhythmias, Supraventricular arrhythmia, Hyperthyroidism, Heart failure, Migraine attacks, etc.

      • Ques : What are the Side Effects of Metosartan 25 tablet?

        Ans : This is a medication which has some commonly reported side effects such as Sexual dysfunction, Impotence, Peyronie's disease, Blurred vision, Dry eyes, Shrinkage of the conjunctiva, Bronchospasm, Shortness of breath, Nausea, etc.

      • Ques : What are the instructions for storage and disposal Metosartan 25 tablet?

        Ans : Store this medication in a cool dry place and keep it in the original pack or container until it is time to take them. Store this medication out of sight and reach of children. Unused medicines should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

      • Ques : How long do I need to use Metosartan 25 Tablet before I see improvement of my conditions?

        Ans : This is a medicine which takes 1 or 2 days before you see an improvement in your health conditions. It would be ideal if you note, it doesn't mean you will begin to notice such health improvement in a similar time span as different patients.

      • Ques : What are the contraindications to Metosartan 25 Tablet?

        Ans : Contraindication to Metosartan. In addition, this medication should not be used if you have the following conditions such as Breastfeeding, Cardiogenic shock, Heart block, Hepatic impairment, Hypersensitivity, etc.

      • Ques : Is Metosartan 25 Tablet safe to use when pregnant?

        Ans : This medication is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

      • Ques : Will Metosartan 25 Tablet be more effective if taken in more than the recommended dose?

        Ans : No, taking higher than the recommended dose of Metosartan can lead to increased chances of side effects such as Muscle cramps, Fatigue, Headache, Cold hands and feet, Nightmares, Slow heart rate, Hypotension, Arterial insufficiency, etc.

      References

      • Telmisartan- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 26 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/telmisartan

      • Telmisartan- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 23 May 2019]. Available from:

        https://www.drugbank.ca/drugs/DB00966

      • Metoprolol- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 May 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/metoprolol

      • Metoprolol- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 23 May 2019]. Available from:

        https://www.drugbank.ca/drugs/DB00264

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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