Metpure -Xl 25Mg Tablet

The primary use of Metpure -Xl 25Mg Tablet is to treat hypertension and angina pectoris. It is also prescribed as a preventive measure to treat myocardial infarction, atrial fibrillation, flutter, and symptomatic treatment of hypertrophic subaortic stenosis.

Metpure -Xl 25Mg Tablet is prescribed to patients to improve heart function and control blood flow through the vessels. The drug helps in the treatment of hypertension, that is, high blood pressure and angina, that is, chest pain.

Metpure -Xl 25Mg Tablet effectively blocks the action of a few body chemicals that occur naturally in the body. The medicine can be taken either before or after a meal. The dosage of the drug depends on the severity of the condition. The doctor may increase dosage as per requirement.

Over dosage of Metpure -Xl 25Mg Tablet should be avoided. In case of accidental overdosage emergency medical care should be acquired. Patients with certain medical problems are generally not advised to take this drug. The medicine is not recommended for patients who have coronary heart disease or blood circulation issues.

If you have suffered a heart attack recently Metpure -Xl 25Mg Tablet may not be the best option for you. Inform your doctor before consuming the drug, if you have clinical conditions like-

• Kidney issues
• Liver problems
• Thyroid disorder
• Any allergies.

Because Metpure -Xl 25Mg Tablet leads to confusion, one should avoid driving in order to avoid accidents. Alcohol should also be avoided when on the drug because liquor can intensify its side effects. The dosage of Metpure -Xl 25Mg Tablet may vary from 100mg to 450mg.

Some medicines which may affect the action of Metpure -Xl 25Mg Tablet are prazosin, terbinafine, bupropion etc. Thus, you should inform your doctor about any medicines that you are currently taking before starting the medicine. In case of a missed drug dose, it should be taken as soon as possible. However, avoid taking the missed dose along with the next dose as it may lead to complications.

• Hypertension

• Angina Pectoris

• Congestive Heart Failure (Chf)

• Migraine Prevention

• Allergy

• Heart Diseases

• Circulatory Disorders

• Heart Rhythm Disorders

• Dizziness

• Slow Heart Rate

• Shortness Of Breath

• Nausea Or Vomiting

• Skin Rash

• Drowsiness

• Decreased Sexual Urge

• Insomnia

• Bradycardia

• Palpitations

• Edema (Swelling)

• How long is the duration of effect?

  The effect lasts for 3 to 6 hours upon oral administration.

• What is the onset of action?

  The effect of Metoprolol (primary constituent of Metpure -Xl 25Mg Tablet) can be observed within an hour of oral administration. .

• Are there any pregnancy warnings?

  This medicine is extremely unsafe to be used during pregnancy. Studies carried out on humans and animals have shown significant adverse effects on the fetus. Doctor consultation is recommended in such cases.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine can be given to the women who are breastfeeding but only after evaluating the benefits and risks with the doctor.

• Does this affect liver function?

  Caution must be taken in patient with liver disease. Adjustment of dose is needed. Kindly consult your doctor before taking this medicine.

• Does this affect kidney function?

  This medicine is found to be safe if used in patients with kidney disease. Adjustment of dose is not needed.

• Is it safe to drive while on this medicine?

  This medicine affects the consciousness of the patient and also the alertness of the patient. Do not drive if you are taking this medicine.

• Is It safe with alcohol?

  This medicine is found to be unsafe if consumed with alcohol.

Below is the list of medicines, which have the same composition, strength and form as Metpure -Xl 25Mg Tablet , and hence can be used as its substitute.

• Metapro Xl 25 MG Tablet

  Micro Labs Ltd

• Starpress Xl 25Mg Tablet

  Lupin Ltd

• Are there any missed dose instructions?

  Take the missed dose as soon as you remember. However, the missed dose can be skipped if it is almost time for the next scheduled dose.

• Are there any overdose instructions?

  In case of overdose, consult your doctor.

This medicine blocks beta receptors sites in the heart, blood vessels, and lungs. It results in inhibition of epinephrine resulting in relaxed blood vessels. Thus pressure is lowered and blood flow to the heart is improved.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Use of alcohol should be avoided while taking this medicine, especially when you start taking the medicine or a change its dosage. Symptoms like headache, dizziness, change in pulse or heart rate should be reported to the doctor.

• Interaction with Medicine

  This medicine must not be concomitantly used along with the following:

  • CYP2D6 enzyme substrate
  • Clonidine:Hypertensive crisis after or during withdrawal of either agent.
  • Drugs which slow AV conduction (digoxin): effects may be additive with beta-blockers.
  • Fluoxetine may inhibit the metabolism of Metpure -Xl 25Mg Tablet resulting in cardiac toxicity.
  • Glucagon: Metpure -Xl 25Mg Tabletmay blunt the hyperglycemic action of glucagon.
  • Hydralazine may enhance the bioavailability of Metpure -Xl 25Mg Tablet.
  • Insulin and oral hypoglycemics: Metpure -Xl 25Mg Tablet may mask tachycardia from hypoglycemia.
  • Metpure -Xl 25Mg Tablet reduces antipyrine's clearance by 18%.
  • NSAIDs (ibuprofen, indomethacin, naproxen, piroxicam) may reduce the antihypertensive effects of beta-blockers.
  • Oral contraceptives may increase the AUC and Cmax of Metpure -Xl 25Mg Tablet.
  • Salicylates may reduce the antihypertensive effects of beta-blockers.
  • Sulfonylureas: Beta-blockers may alter response to hypoglycemic agents.
  • Verapamil or diltiazem may have synergistic or additive pharmacological effects when taken concurrently with beta-blockers; avoid concurrent I.V. use.
  • Amlodipine, Diltiazem, Aminophylline, Ergotamine also interacts with this medicine, thus should be avoided.

• Interaction with Disease

  This medication interacts with Asthma, Heart Block, Diabetes, Liver disease, Glaucoma and High cholesterol and fat.

• Interaction with Food

  This medicine should be used with caution if you are taking vitamin and mineral supplement. Report the usage of supplements to the doctor so that dose adjustments and safety monitoring can be done. There should be a gap of at least 2 hours between the consumption of these two medicines.

• Ques : What is Metpure -Xl 25Mg Tablet?

  Ans : This is a medication which has Metoprolol Succinate as an active element present. Metpure is a long-acting beta obstructor that works certainly on the heart. It performs its action by slowing down the heart rate and makes the heart more efficient at pumping blood around the body.

• Ques : What are the uses of Metpure -Xl 25Mg Tablet?

  Ans : This is a medication, which is used for the treatment and prevention from conditions such as chest pain (Angina), heart failure and high blood pressure.

• Ques : What are the Side Effects of Metpure -Xl 25Mg Tablet?

  Ans : Metpure is a medication which has some commonly reported side effects such as Fatigue, Headache, Slow heart rate, Dizziness, Stomach pain, Nausea, Shortness of breath, and Cold extremities.

• Ques : What are the instructions for storage and disposal Metpure -Xl 25Mg Tablet?

  Ans : Store this medication in a cool dry place and keep it in the original pack or container until it is time to take them. Store this medication out of sight and reach of children. Unused medicines should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

• Ques : How long do I need to use Metpure -Xl 25Mg Tablet before I see improvement of my conditions?

  Ans : This a medicine which takes 1 or 2 days before you see an improvement in your health conditions. It would be ideal if you note, it doesn't mean you will begin to notice such health improvement in a similar time span as different patients.

• Ques : What are the contraindications to Metpure -Xl 25Mg Tablet?

  Ans : Contraindication to Metpure. In addition, this medication should not be used if you have the following conditions such as Active liver disease, Aliskiren, Bilateral renal artery stenosis, Breastfeeding, Cardiogenic shock, etc.

• Ques : Is Metpure -Xl 25Mg Tablet safe to use when pregnant?

  Ans : This medication is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

• Ques : Will Metpure -Xl 25Mg Tablet be more effective if taken in more than the recommended dose?

  Ans : No, taking higher than the recommended dose of Metpure can lead to increased chances of side effects such as Type 2 diabetes mellitus, Myopathy, Joint pain, Diarrhea, Upset stomach, Muscle pain, Nausea, Headache, etc.

• Metoprolol- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 May 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/metoprolol

• Metoprolol- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 23 May 2019]. Available from:

  https://www.drugbank.ca/drugs/DB00264

• Important Information About Metoprolol- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 23 May 2019]. Available from:

  https://www.drugsbanks.com/important-information-about-metoprolol/