Metronidazole 400 MG Tablet

Metronidazole 400 MG Tablet is primarily prescibed to treat bacterial and parasitic infection in the patient. It contains metronidazole as active drug in it. This medicine is used to treat infections of the blood, brain, lung, bones, genital tract, pelvic area, stomach area and intestine.

The drug is an anti-protozoal used either on its own or in combination in the treatment of infections in the stomach and genital areas. The medication is prescribed in the treatment of Amebiasis, Trichomoniasis, Bacterial Vaginosis, Bacterial infections and Surgical prophylaxis. This medication is not recommended with alcohol as it can cause severe discomfort and reactions.

It is also prescribed to treat gum ulcers, other dental infections, infected leg ulcers and pressure sores. It is also helpful in preventing infections after surgery. Exercise caution if you are pregnant or breastfeeding a baby. Before starting the course of treatment, inform your doctor if you have:

• Any allergies
• Liver disease
• Nerve disorders
• Stomach infections
• Crohn’s disease
• Epilepsy or
• Seizures

This medication may have a lot of side effects and I should be taken under medical prescription some side effects include agitation, blurred vision, burning or tingling sensation of hands and feet, fevers and chills, skin rash, vaginal irritation, loss of appetite, constipation, yellow coloured eyes or skin and abdominal pain.

If the medication is taken while there is alcohol present in the system it can cause palpation, warmth, headache and breathing difficulty. This medication does not cause habit-forming tendencies. This drug is not recommended for women who just got pregnant but can be used in the later term of pregnancy.

Breastfeeding mothers should avoid this drug as it can be passed down through milk and cause severe indigestion or diarrhoea. This medication may lower blood count and convulsions.

Use Metronidazole 400 MG Tablet with caution in patients with liver impairment due to potential accumulation, blood dyscrasias; a history of seizures, congestive heart failure, or other sodium retaining states; reduce dosage in patients with severe liver impairment, CNS disease, and severe renal failure (Clcr <10 mL/minute).

If H. pylori is not eradicated in patients being treated with Metronidazole 400 MG Tablet in a regimen, it should be assumed that metronidazole-resistance has occurred and it should not again be used; seizures and neuropathies have been reported especially with increased doses and chronic treatment; if this occurs, discontinue therapy.

The dosage will be prescribed by your doctor determining your age, gender, overall health and the severity of your condition. The usual dosage in adults for a bacterial infection is about 7.5 mg orally every 6 hours over a period of 7-10 days. The dose for other treatments varies from one person to another. In case of a drug overdose, seek medical attention immediately.

• Amebiasis

• Trichomoniasis

• Bacterial Vaginosis

• Bacterial Infections

• Surgical Prophylaxis

• Giardiasis

• Peptic Ulcer

• Allergy

• Pregnancy

• Dizziness

• Headache

• Nausea

• Diarrhoea

• Loss Of Appetite

• Vomiting

• Ataxia

• Seizures

• Dry Mouth

• Metallic Taste

• Dark Urine

• Peripheral Neuropathy

• Abdominal Pain

• How long is the duration of effect?

  The effect of this medicine lasts for about 24 hours.

• What is the onset of action?

  The top effect of this medication is usually observed within 1 to 2 hours after administration.

• Are there any pregnancy warnings?

  This medicine is not recommended in the first trimester of pregnancy to treat bacterial vaginosis and trichomoniasis. It can be used in the second and third trimesters of pregnancy only if clearly needed.

• Is it habit forming?

  No habit forming tendencies are reported for this drug.

• Are there any breast-feeding warnings?

  This medicine is known to excreted through the breastmilk. It is used in breastfeeding women only if clearly needed. Breastfeeding should be avoided for 24 hours after single-dose maternal treatment. Monitoring of candidal infections and diarrhea is necessary.

• Does this affect kidney function?

  Dose adjustment is required in case of renal dysfunction. Consult a doctor before taking this medicine.

• Does this affect liver function?

  The medication is know to cause liver injury and liver treatment of baseline liver enzymes if you are about to start this medication. Consult your doctor if you want to seek other alternative or want to be on a safer side while under this medication. You should discontinue the treatment if you see the state of your liver deteriorating.

• Is It safe with alcohol?

  It is suggested to avoid, Metronidazole 400 MG Tablet along with alcohol as it may cause side effects that can worsen the condition of the patients. Kindly consult your doctor before taking this medication.

• Is it safe to drive while on this medicine?

  This medicine cause effects which affects the alertness of the patients, thus the patient must not drive after taking Metronidazole 400 MG Tablet.

Below is the list of medicines, which have the same composition, strength and form as Metronidazole 400 MG Tablet , and hence can be used as its substitute.

• Aristogyl 400 MG Tablet

  Aristo Pharmaceuticals Pvt.Ltd

• Balgyl 400 MG Tablet

  Micro Labs Ltd

• Emnac 400 MG Tablet

  Emcure Pharmaceuticals Ltd

• Flagyl 400 MG Tablet

  Abbott Healthcare Pvt. Ltd

• Metron 400 MG Tablet

  Alkem Laboratories Ltd

• Missed Dose instructions

  If you miss a dose, take it as soon as you remember.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

This medicine works by getting into a product which interacts with DNA to cause a loss of helical DNA structure and strand breakage resulting in inhibition of protein synthesis and cell death in the susceptible organism.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  A disulfiram-like reaction characterized by flushing, headache, nausea, vomiting, sweating or tachycardia; patients should be warned to avoid alcohol during and 72 hours after therapy

• Interaction with Lab Test

  Metronidazole 400 MG Tablet may interfere with AST, ALT, triglycerides, glucose, and LDH testing.

• Interaction with Medicine

  Metronidazole 400 MG Tablet may interact with CYP2C9 enzyme substrate; CYP2C9, 3A3/4, and 3A5-7 enzyme inhibitor. The drugs that you should avoid while taking this medication are Warfarin, Ethinyl Estradiol, Atorvastatin, and Disulfiram. Consult your doctor if you are under any other medication to avoid unnecessary complications.

• Interaction with Food

  Information not available.

• Ques : What is Metronidazole 400 MG Tablet?

  Ans : Metronidazole tablet is a medication which has Metronidazole as an active ingredient present in it. This medicine performs its action by treating bacterial and viral infections.

• Ques : What are the uses of Metronidazole 400 MG Tablet?

  Ans : Metronidazole tablet is used for the treatment and prevention from conditions and symptoms of diseases like gynecologic infections, endocarditis and bacterial septicemia.

• Ques : What are the Side Effects of Metronidazole 400 MG Tablet?

  Ans : Constipation, dizziness, vaginal irritation, abdominal pain and dry mouth are common side effects.

• Ques : What are the instructions for storage and disposal Metronidazole 400 MG Tablet?

  Ans : Metronidazole tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Ques : Should I use Metronidazole 400 MG Tablet empty stomach, before food or after food?

  Ans : Taking this medication with the food will be much beneficial than using it on an empty stomach, as the mechanism of the medication requires nutrients to carry out the reaction.

• Ques : How long do I need to use Metronidazole 400 MG Tablet before I see improvement of my conditions?

  Ans : The time taken by this medication to improve your health is unknown. It is advised to use this medication for the time period it is prescribed by your doctor.

• Ques : Is there any food or drink I need to avoid?

  Ans : You can follow your normal diet under the usage of this medication. Avoidance of any specific food product is not required.

• Ques : Will Metronidazole 400 MG Tablet be more effective if taken in more than the recommended dose?

  Ans : There is no need to take this medication more than its recommended doses. Taking over-dosage of this medication may trigger side effects.

• Ques : Is Metronidazole 400 MG Tablet prescribed for stomach infections and infections of gum and cavities?

  Ans : Yes, this drug is prescribed for infections of stomach, gum and cavities. However, one should take medical help before consuming Metronidazole 400 MG Tablet.

• Ques : Can the consumption of this medication stopped suddenly?

  Ans : Some medications have rebound effects if stopped suddenly. For recommendations specific to your body, health and other medications, please take medical help.

• Ques : Is Metronidazole 400 MG Tablet recommended for loose motions?

  Ans : Yes, it can be used in loose motion. This drug belongs to the group of antiprotozoal that helps in the treatment of several infections in the genital areas and stomach.

• Ques : Is Metronidazole 400 MG Tablet used for chest infections?

  Ans : This medication is rarely used for chest infections. The medicine should be taken for chest infections strictly under the guidance of a doctor.

• Ques : Can the use of Metronidazole 400 MG Tablet cause metallic taste?

  Ans : Yes, this medicine may cause a temporary metallic taste. YOu can reduce this metallic taste by staying hydrated, brushing teeth after meals and chewing sugar-free gum or mints.

• Ques : Can I stop taking Metronidazole 400 MG Tablet when I feel better?

  Ans : No, do not stop taking this medicine and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured. Hence, if you stop taking the medicine before completing the course, your infection may come back.

• Ques : What if there is no improvement after using Metronidazole 400 MG Tablet?

  Ans : Inform your doctor if you didn't feel better after finishing the full course of treatment.

• Metronidazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 23 Nov 2021]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/metronidazole

• Flagyl 200mg Tablets- EMC [Internet]. www.medicines.org.uk. 2021 [Cited 23 Nov 2021]. Available from:

  https://www.medicines.org.uk/emc/product/9237/smpc

• METRONIDAZOLE BENZOATE powder- Daily Med [Internet]. dailymed.nlm.nih.gov. 2019 [Cited 23 Nov 2021]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=58b338e7-e114-413e-b9bd-0e5f7ec037c7