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Overview

Mifegest 200 MG Tablet

Manufacturer :  Zydus Cadila
Medicine Composition :  Mifepristone
Prescription vs OTC : Prescription by Doctor not required

About Mifegest 200 MG Tablet

It is a medication that is used to bring about abortion in only those women who have been pregnant for about seven weeks or fifty days. It is taken along with the combination of misoprostol.

This medication interferes with the hormones that help in pregnancy continuation. It is a synthetic steroid. A doctor should be consulted before taking this medicine and should not be self-prescribed under any circumstances.

Inform your doctor, if you are older than 35 years, you smoke more than 10 cigarettes a day, you have asthma problem or have any kind of lungs, liver or kidney diseases, you are pregnant outside the uterus region, you are allergic to any of the medication content or if you are taking any anticoagulants.

A women should not take Mifegest 200 MG Tablet if she is/has:

  • An ectopic pregnancy
  • Treated with long-term corticosteroid medicines
  • Inherited porphyria
  • Problem with the adrenal glands
  • Bleeding problems or is taking anticoagulant (blood-thinning) medication
  • An intrauterine device (IUD) in place, it must be removed before taking this medication.

The dose that is generally given is 200 MG orally once and after say about 2-3 days the dosage is increased to about 800 MG every 24 to 48 hours. However, these are not the dosage patterns that you should assign to yourself and should always consult a doctor.

This medication is prescribed for the purpose of termination of pregnancy which are less than 10 weeks old. It is also used for labour induction in case of a getup death. It is also used for managing elevated sugar levels in patients having Cushing’s syndrome coupled with glucose intolerance type diabetes.

The dosage for this medication will be prescribed by your doctor depending on your age, weight, health, and current condition. After 7 days, you must visit your doctor to check if you are still pregnant. Also, track the quantity and frequency of the bleeding.

    What are the uses of Mifegest 200 MG Tablet

    What are the contraindications of Mifegest 200 MG Tablet ?

    What are the side effects of Mifegest 200 MG Tablet ?

    Key highlights of Mifegest 200 MG Tablet

    • How long is the duration of effect?

      The effect of this medication last for about 7-10 days on an average.

    • What is the onset of action?

      The medication reaches the peak level in say about 1-2 hours and is immediately absorbed in the bloodstream.

    • Are there any pregnancy warnings?

      The medication is acceptable for medical termination of pregnancy which is about 63-70 days old only. A pregnant woman who is not looking for an abortion should completely avoid taking it and should not used this medication for the purpose of high sugar level along with elevated cortisol.

    • Is it habit forming?

      This medication is not habit forming.

    • Are there any breast-feeding warnings?

      This medication should be avoided by the women who are breast feeding. If this medication is taken during an emergency, breast feeding should be discontinued immediately. Consult a doctor for the risks and benefits.

    • Is It safe with alcohol?

      Consumption of alcohol along with this medicine is found to be safe.

    • Is it safe to drive while on this medicine?

      The side effects of this medication may cause sleepiness, dizziness. Hence, driving after taking such medicine should be avoided.

    • Does this affect kidney function?

      No information available. Consult a doctor if anything unusual happens.

    • Does this affect liver function?

      No information available. Consult a doctor if anything unusual is noticed.

    What are the substitutes for Mifegest 200 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Mifegest 200 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      When using it for elevated sugar levels, the missed dose should be taken as soon as possible and if it is almost time for the next dose, then it should be avoided. In case of termination of pregnancy, it is a single dose therapy.

    • Are there any overdose instructions?

      If there is a situation of overdose then immediately contact your doctor.

    How does this medication work?

    This medication blocks the effect of progesterone by competitively binding to the specific receptors and sensitizing the inner linings of the uterus inducing bleeding and contractions. It also blocks the effect of cortisol at the specific receptors and reducing the effect caused by an excess of this hormone.

      What are the interactions of Mifegest 200 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Medicine

        Mifegest 200 MG Tablet severely interacts with the following drugs- dexamethasone, erythromycin, hydrocortisone, ketoconazole, simvastatin, pimozide, warfarin and ergotamine.

      • Interaction with Disease

        This medication is not prescribed for people who are suffering from unexplained vaginal bleeding, adrenal gland malfunction or porphyria which is a genetic disorder of the blood having adverse reactions on the skin as well as the nervous system.

      • Interaction with Food

        Grapefruit juice

        It is recommended that you avoid grapefruit juice while taking this medication. It may modify the effects of the drug.

      FAQs about Mifegest 200 MG Tablet

      • Ques : What is Mifegest 200 MG Tablet?

        Ans : This medication belongs to the class of synthetic steroids which are used for abortion or termination of early pregnancy. It is used along with misoprostol. It functions by inhibiting the hormone that ensures the continuity of pregnancy. Patients allergic to the ingredients of this medication and the women who are pregnant outside the uterus region should take this medicine after consulting a doctor.

      • Ques : What is Mifegest 200 MG Tablet used for?

        Ans : This medication is used for the treatment and prevention of condition or symptoms like managing elevated blood sugar levels in patients having Cushing's syndrome combined with type 2 diabetes mellitus or glucose intolerance. It is mainly used in the termination of pregnancy which are less than 10 weeks old. In the case of Cushing’s Syndrome, the tablet should be taken with food by swallowing it.

      • Ques : What are the side effects of Mifegest 200 MG Tablet?

        Ans : Common Side effects of taking this medication are Abdominal Pain And Cramps, Uterine Cramping, Nausea Or Vomiting, Headache, Dizziness and Diarrhoea.

      • Ques : What will happen after taking Mifegest 200 MG Tablet?

        Ans : It can be taken before the 10th week of pregnancy to abort the growth of the fetus. Women more than 10 weeks pregnant should consult a doctor for Abortion. It is observed that the women who are less than 10 weeks pregnant have achieved desired results in about 8 to 10 days.

      • Ques : What is you miss a dose of Mifegest 200 MG Tablet?

        Ans : If you accidentally miss a dose of this medication, as it is advised to take as soon as possible to avoid serious effects.

      • Ques : Is Mifepristone(Primary constituent of Mifegest 200 MG Tablet) and Misoprostol available/ legal in India?

        Ans : Yes, Mifepristone and Misoprostol medications are available and legal in India.

      • Ques : Can I take Ibuprofen with Mifepristone (Primary constituent of Mifegest 200 MG Tablet)?

        Ans : Yes, it is safe to consume Ibuprofen with Mifepristone as it may not cause any side effects.

      • Ques : Can you take Mifepristone (Primary constituent of Mifegest 200 MG Tablet) with water?

        Ans : Yes. It is advised to consume Mifepristone with water.

      References

      • KORLYM- mifepristone tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2016 [Cited 24 April 2019]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=542f3fae-8bc8-4f00-9228-e4b66c9ad6a9

      • Mifepristone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/mifepristone

      • Mifegyne- EMC [Internet]. www.medicines.org.uk. 2015 [Cited 23 April 2019]. Available from:

        https://www.medicines.org.uk/emc/product/3783

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Content Details
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Yuvraj Arora MongaMD-Pharmacology, MBBSSexology
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