Mifepristone
About Mifepristone
Mifepristone is a steroid used to terminate a pregnancy. It inhibits the secretion of progesterone that is needed to maintain the pregnancy. It should only be used if the pregnancy is within 70 days (10 weeks).
It is recommended that you do not use it if you are over 10 weeks pregnant. It can only be bought with a prescription. For a complete medical termination of the pregnancy, Mifepristone is used with Misoprostol. Mifepristone is taken as a tablet once. After 24-48 hours, Misoprostol is taken.
A women should not take Mifepristone if she is/has:
- An ectopic pregnancy
- Treated with long-term corticosteroid medicines
- Inherited porphyria
- Problem with the adrenal glands
- Bleeding problems or is taking anticoagulant (blood-thinning) medication
- An intrauterine device (IUD) in place, it must be removed before taking this medication.
The dosage for this medication will be prescribed by your doctor depending on your age, weight, health, and current condition. After 7 days, you must visit your doctor to check if you are still pregnant. Also, track the quantity and frequency of the bleeding.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.
What are the uses of Mifepristone
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.
What are the contraindications of Mifepristone ?
Unexplained Vaginal Bleeding
Chronic Adrenal Failure
Other Bleeding Disorders
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.
What are the side effects of Mifepristone ?
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.
Key highlights of Mifepristone
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 7-10 days.
What is the onset of action?
Mifepristone starts producing the required effects within 1-2 hours of administration.
Are there any pregnancy warnings?
It is advised that Mifepristone is used to terminate a pregnancy that is within 63-70 days. Use of this drug to control elevated blood sugar level should not be done if you are pregnant.
Is it habit forming?
It is not habit forming.
Are there any breast-feeding warnings?
It is recommended that you do not breastfeed your child if the administration of this drug is highly necessary.
Is It safe with alcohol?
Interaction with alcohol is still unknown. Consult your doctor before proceeding
Is it safe to drive while on this medicine?
Mifepristone may cause sleepiness. It is advised that you do not drive if you are experiencing this side-effect.
Does this affect kidney function?
There is no reported impairment to the kidney functioning.
Does this affect liver function?
There is no reported impairment to the liver functioning.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.
What are the dosage instructions?
Are there any missed dose instructions?
For termination of pregnancy, it is a single dose therapy; it is not possible to miss a dose. If you are taking it for controlling blood sugar level and miss a dose, take it as soon as possible. But do not double dose.
Are there any overdose instructions?
If you overdose on Mifepristone, contact your physician right away.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.
Where is the Mifepristone approved?
India
United States
Japan
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.
Medicines containing Mifepristone
Below is the list of medicines, which contains Mifepristone as ingredient
- Festone Combi Kit
Leeford Healthcare Ltd
- Undo 200 MG Tablet
Fdc Ltd
- Pri Vc 200 MG Tablet
Alembic Ltd
- Mifepro 200 MG Tablet
Hll Life Care Ltd
- Fibristone 25Mg Tablet
Jagsonpal Pharmaceuticals Ltd
- Mefetrac 200 MG Kit
Fourrts India Laboratories Pvt. Ltd
- Mifegest 200 MG Tablet
Zydus Cadila
- Pregnot Kit 200 MG Tablet
Lupin Ltd
- Unwanted 200 MG Tablet
Mankind Pharmaceuticals Ltd
- Mtp Kit
Cipla Ltd
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.
How does this medication work?
This medication works by blocking the effect of progesterone by competitively binding to the specific receptors and sensitizing the inner linings of the uterus inducing bleeding and contractions. It also blocks the effect of cortisol at the specific receptors and reducing the effect caused by an excess of this hormone.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.
What are the interactions of Mifepristone ?
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
- test
Interaction with Alcohol
Interaction with Medicine
Mifepristone severely interacts with the following drugs- dexamethasone, erythromycin, hydrocortisone, ketoconazole, simvastatin, pimozide, warfarin and ergotamine.
Interaction with Food
It is recommended that you avoid grapefruit juice while taking this medication. It may modify the effects of the drug.
Interaction with Disease
There are no known disease interactions.
FAQs about Mifepristone
Ques : What is Mifepristone?
Ans : This medication helps in medical termination of the pregnancy. It blocks the effect of progesterone (a female sex hormone) which is required for maintenance of pregnancy.
Ques : How and in what dose should I consume?
Ans : This medication can be taken orally with water. It should be taken under the supervision of your medical health practitioner.
Ques : What should I expect after taking Mifepristone?
Ans : After consuming this drug, you may or may not experience vaginal bleeding. After 48 hours of taking this drug, your medical practitioner shall examine you and may prescribe you another medicine for complete termination of pregnancy.
Ques : Can Mifepristone affect my future chances of getting pregnant?
Ans : No, Your future chances of conceiving are as equal as of those who have not taken this drug.
Ques : What are the common side effects of taking Mifepristone?
Ans : Most common side effects include vaginal bleeding and abdominal cramping. The other common side effects include diarrhea, nausea, & vomiting.
References
Mifepristone-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:
https://druginfo.nlm.nih.gov/drugportal/name/mifepristone
Mifepristone-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:
https://go.drugbank.com/drugs/DB00834
MIFEPRISTONE tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:
https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=MIFEPRISTONE
Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.
Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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