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Overview

Miofree A 100 Mg/4 Mg Tablet

Manufacturer :  Lupin Ltd
Medicine Composition :  Aceclofenac, Thiocolchicoside
Prescription vs OTC : Prescription by Doctor not required

About Miofree A 100 Mg/4 Mg Tablet

Miofree A 100 Mg/4 Mg Tablet is chiefly known as a pain killer. It is primarily used to treat pain caused due to muscle spasm. This medication is a combination of Aceclofenac and Thiocolchicoside.

These two drug belongs to the class of non-steroidal anti-inflammatory drugs and natural anti-inflammatory glycosides, respectively. The drug combination works together and helps in improving muscle movement and also relieves discomfort and pain associated with the spasm.

This drug works by blocking the effect of cyclooxygenase (COX) enzymes which make chemical prostaglandins at sites of injury or damage causing pain, swelling and inflammation.

The side effects of this drug include nausea, vomiting, diarrhoea, flatulence, constipation, dyspepsia, drowsiness, confusion, etc. You should not be taking this medicine if–

  • You are allergic to this drug or other anti-inflammatory painkillers.
  • You ever had a problem with stomach or duodenal bleeding.
  • You have a heart condition or impaired kidney or liver function.
  • You are pregnant or breastfeeding woman.
  • You have high blood pressure or blood clotting problems.

This medication interacts with medicines like lithium, digoxin, corticosteroids, antihypertensives, etc and certain diseases like asthma, gastrointestinal toxicity. It can be taken with food or after food.

Drinking an adequate amount of water minimises chances of indigestion and stomach irritations. The duration and amount of medicine should be followed as per the doctor’s prescription.

    What are the uses of Miofree A 100 Mg/4 Mg Tablet

    What are the contraindications of Miofree A 100 Mg/4 Mg Tablet ?

    What are the side effects of Miofree A 100 Mg/4 Mg Tablet ?

    Key highlights of Miofree A 100 Mg/4 Mg Tablet

    • How long is the duration of effect?

      The effect lasts for a duration of 12 to 16 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed in 1.5 to 3 hours.

    • Are there any pregnancy warnings?

      This medicine is not recommended for pregnant women.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medicine is not recommended for breastfeeding women.

    What are the substitutes for Miofree A 100 Mg/4 Mg Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Miofree A 100 Mg/4 Mg Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose can be taken as soon as you remember.

    • Are there any overdose instructions?

      A doctor should be contacted immediately if an overdose is suspected.

    How does this medication work?

    This medication is a combination of Aceclofenac and Thiocolchicoside, thus it works via a dual mechanism of action. The former drug, Aceclofenac, belongs to the class of a non-steroidal anti-inflammatory drug that helps relieve pain. Prostaglandins are responsible for pain, inflammation, swelling and fever. It inhibits the action of cyclooxygenase in the brain which is involved in the production of prostaglandins.

    The latter constituent, Thiocolchicoside, is a derivative of glucoside, colchicoside that is contained within the Colchicum autumnale plant. It is a type of synthetic sulphur derivative. This medication has a high affinity for g-aminobutyric acid receptors. It activates GABA pathways and acts on the muscular contractures.

      What are the interactions of Miofree A 100 Mg/4 Mg Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Ethanol

        This medicine should not be consumed with alcohol.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Food

        Food

        Information not available.
      • Interaction with Disease

        Disease

        Patients suffering from asthma and impaired kidney function should exercise caution.

      FAQs about Miofree A 100 Mg/4 Mg Tablet

      • Ques : What is Miofree A 100 Mg/4 Mg Tablet?

        Ans : This medication performs its action by obstructing the release of pain and fever chemical messengers.

      • Ques : What are the uses of Miofree A 100 Mg/4 Mg Tablet?

        Ans : This medicine used for the treatment of osteoarthritis, muscle stiffness, rheumatoid arthritis and joint stiffness.

      • Ques : What are the Side Effects of Miofree A 100 Mg/4 Mg Tablet?

        Ans : Heartburn, appetite loss, diarrhea and stomach disorders, nausea, vomiting and sleepiness are common side effects.

      • Ques : What are the instructions for storage and disposal Miofree A 100 Mg/4 Mg Tablet?

        Ans : Miofree tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

      • Ques : How long do I need to use Miofree A 100 Mg/4 Mg Tablet before I see improvement of my conditions?

        Ans : The time period to use this medication is around 1 to 2 days to make an improvement in the condition.

      • Ques : Is there any food or drink I need to avoid?

        Ans : You can follow your normal diet under the usage of this medication.

      • Ques : Will Miofree A 100 Mg/4 Mg Tablet be more effective if taken in more than the recommended dose?

        Ans : There is no need to take this medication more than its recommended doses.

      References

      • Aceclofenac- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/aceclofenac

      • Aceclofenac- DrugBank [Internet]. Drugbank.ca. 2010 [Cited 1 February 2020]. Available from:

        https://www.drugbank.ca/drugs/DB06736

      • Thiocolchicoside- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/thiocolchicoside

      • Thiocolchicoside- DrugBank [Internet]. Drugbank.ca. 2016 [Cited 1 February 2020]. Available from:

        https://www.drugbank.ca/drugs/DB11582

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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