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Overview

Nac Injection

Manufacturer :  Systopic Laboratories Pvt Ltd
Medicine Composition :  Diclofenac
Prescription vs OTC : Prescription by Doctor required

About Nac Injection

Nac Injection is a non-steroidal anti-inflammation medication which is used as a painkiller in the treatment of conditions like Gout, migraines, Rheumatoid Arthritis, fever and to some degree of muscle spasms and joints. It is known to effectively relieve pain, swelling and joint stiffness caused by arthritis.

This is a prescription drug and has some severe side effects such as abdominal pain, constipation, Diarrhoea, Nausea, and vomiting, these side effects can generally be avoided by taking the drug with food. The consumption of alcohol is not advisable as it may cause dizziness and in severe cases gastrointestinal bleeding.

The medication is not recommended for pregnant women and is known to pass down through milk while breast-feeding. Patients suffering from peptic ulcer and have undergone Coronary artery bypass are not recommended to this medication.

You must inform your doctor before initiating this medication, if you suffer from various conditions such as

  • Asthma
  • Impaired kidney function
  • Heart diseases.

The strength of this medication to be prescribed depends upon the age, gender, and physical conditions of the patient. It is not recommended if you are expecting or planning on becoming pregnant anytime soon. During pregnancy, it is not recommended in the first and last trimesters of the pregnancy due to the possible harm of the fetus.

Symptoms of Nac Injection overdose include acute renal failure, vomiting, drowsiness, leukocytosis. Management of a nonsteroidal anti-inflammatory drug (NSAID) intoxication is primarily supportive and symptomatic.

Fluid therapy is commonly effective in managing the hypotension that may occur following an acute NSAID overdose, except when this is due to an acute blood loss.

Take this medication exactly as directed; do not increase dose without consulting prescriber. Do not crush or chew tablets. Take with 8 ounces of water, along with food or milk products to reduce GI distress.

Maintain adequate fluid intake (2-3 L/day of fluids unless instructed to restrict fluid intake). Avoid excessive alcohol, aspirin and aspirin-containing medication, and all other anti-inflammatory medications unless consulting prescriber.

GI bleeding, ulceration, or perforation can occur with or without pain; discontinue medication and contact prescriber if persistent abdominal pain or cramping, or blood in stool occurs.

Nac Injection may rarely cause agranulocytosis; use caution with clozapine and carbamazepine; may decrease the clearance of lithium resulting in elevated serum levels and potential toxicity; monitor serum lithium levels.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the uses of Nac Injection

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the contraindications of Nac Injection ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the side effects of Nac Injection ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Key highlights of Nac Injection

    • How long is the duration of effect?

      The effect generally lasts for about 2-3 hours after intake of the medication.

    • What is the onset of action?

      The medication having a potassium base usually starts its action within 10-15 minutes of intake as it is easier for the absorption in the the stomach.

    • Are there any pregnancy warnings?

      This medication is generally not recommended for pregnant women as it can cause harm to the developing child and alter the developmental progress.

    • Is it habit forming?

      No habit forming tendencies were reported and is not addictive.

    • Are there any breast-feeding warnings?

      Breast-feeding mother are not advised to take this medication as traces of the drug passes on through breast milk.

    • Is It safe with alcohol?

      It is not recommended with alcohol as it may interact and cause in the increase of side effects such as dizziness, fatigue, weakness and sever gastrointestinal bleeding. This will do more harm than good and is therefore not suggested that the two be mixed together.

    • Is it safe to drive while on this medicine?

      It may cause side effects like blurred vision, drowsiness or dizziness in some patients which affect their ability to drive.

    • Does this affect kidney function?

      Caution must be taken in patients with kidney disease. Thus dose adjustment is needed. Please consult your doctor before taking this medicine.

    • Does this affect liver function?

      Caution must be taken in patients with liver disease. Thus dose adjustment is needed. Please consult your doctor before taking this medicine.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the substitutes for Nac Injection ?

    Below is the list of medicines, which have the same composition, strength and form as Nac Injection , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you have missed a dose then take it as soon as you remember, do not overlap or take multiple doses to make up for the missed dose.

    • Are there any overdose instructions?

      If there are symptoms of overdose then contact the nearest emergency room and get professional help.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Where is the Nac Injection approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    How does this medication work?

    This medication works by inhibiting an enzyme named Cyclooxygenase which is responsible for the formation of prostaglandin. Prostaglandin is a major contributor to the process of inflammation and pain sensation in the body.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

      What are the interactions of Nac Injection ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        The drug should not consumed with or under the effect of alcohol as they react and cause side effects like nausea, dizziness and severe indigestion.
      • Interaction with Medicine

        • Painkiller such as aspirin, ibuprofen and naproxen should be avoided as it increases the chance of side effects.
        • Blood thinner are also not recommended if you are hypertensive you should consult your doctor before starting this medication.
        • Increased toxicity of digoxin, methotrexate, cyclosporine, lithium, insulin, sulfonylureas, potassium-sparing diuretics, aspirin.
      • Interaction with Disease

        Use with caution in patients with congestive heart failure, dehydration, hypertension, decreased renal or hepatic function, history of GI disease, or those receiving anticoagulants.
      • Interaction with Food

        One should have ample food while taking this medication as it will help in the absorption of the medication and increase the effectiveness.

      FAQs about Nac Injection

      • Ques : What is Nac Injection?

        Ans : Nac Injection is a drug which belongs to the class of Non-steroidal anti-inflammatory drug.

      • Ques : What Nac Injection is used for?

        Ans : It works as a pain killer and prescribed in numerous clinical conditions related to pain and inflammation like Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis, Dysmenorrhea, Mild To Moderate Pain, Migraine, Bursitis, Tendinitis, etc.

      • Ques : Is Nac Injection a narcotic?

        Ans : No this medicine is not a narcotic. It belongs to NSAIDs group of medicines.

      • Ques : What are the side effects of Nac Injection?

        Ans : Side effects include abdominal pain, constipation, diarrhoea, nausea, skin rash, tinnitus, etc.

      • Ques : Is it safe to take Nac Injection daily for a long time?

        Ans : This medicine is safe to use if taken as per doctor’s prescription. However, this medicine is unlikely to harm you, but it’s suggested to take it for the period of time you need it.

      • Ques : Is Nac Injection a good painkiller?

        Ans : This drug is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains and other injuries.

      • Ques : Is Nac Injection a narcotic?

        Ans : No, Nac Injection is not a narcotic. It belongs to a non-steroidal anti-inflammatory drugs group of medicines.

      • Ques : Does Nac Injection get you high?

        Ans : No, this drug does not get you high. If, however, you do not feel well, consult your medical practitioner.

      • Ques : Can Nac Injection hurt your kidneys?

        Ans : Long-term use and high doses of this medication may cause renal problems such as protein or blood in urine and painful urination.

      • Ques : Does Nac Injection make you drowsy?

        Ans : This drug causes drowsiness and also dizziness, fatigue (tiredness) and visual disturbances. However, it is not very common and may not affect everyone. If you experience these symptoms avoid driving or operating heavy machinery.

      • Ques : What is the most important information I need to know about Nac Injection?

        Ans : You must know that this drug may increase your chance of having a heart attack or stroke. The risk is more if you take higher doses and have been using the medicine for a longer time.

      • Ques : Can Nac Injection be taken during pregnancy?

        Ans : You should not take this medication during the last 3 months of pregnancy as it may cause harmful effects on your baby. The use of this drug can also lead to reduced labor (premature delivery).

      References

      • Diclofenac- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 23 Nov 2021]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/diclofenac

      • DICLOFENAC SODIUM- diclofenac gel- Daily Med [Internet]. dailymed.nlm.nih.gov. 2018 [Cited 24 Nov 2021]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f64b68a5-d6d2-4e92-87e7-90af04c1f9db

      • Diclofenac 1% Gel- EMC [Internet]. www.medicines.org.uk. 2021 [Cited 24 Nov 2021]. Available from:

        https://www.medicines.org.uk/emc/product/12073/smpc

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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