Napra D 500Mg Tablet

Napra D 500 MG Tablet is a combination medication, primarily prescribed for the treatment and prevention of migraine attack. This medication is comprized of two drugs, Naproxen and Domperidone, which belongs to the class of a non-steroidal anti-inflammatory drugs and dopamine antagonists, respectively.

On using this medicine some side effects like stomach upset, nausea, vomiting, heartburn, drowsiness, headache may occur. Serious side effects may include easy bruising or bleeding, painful swallowing, ringing in the ears, signs of kidney problems, mood changes, unusual tiredness, swelling of the ankles, feet and hands, unexplained stiff neck, unexplained weight gain and vision changes.

To ensure this medicine is safe for you tell your doctor if you have asthma, blood disorders, nasal polyps, liver disease, heart disease, stroke, high blood pressure or throat, stomach or intestinal problems.

Take this Napra D 500 by mouth as instructed by your doctor, usually 2 or 3 times in a day. Remember to not lie down for a minimum of 10 minutes after taking it. To prevent stomach upset, take this drug with milk, food or an antacid.

To reduce your risk of side effects, start the medication at the lowest effective dose for a short period of time. Take a higher dosage if needed, after consulting with a doctor.

Also Read: Uphold Tablet Uses

• Migraine Headache

• Migraine Prophylaxis

• Nausea Or Vomiting

• Allergy

• Dry Mouth

• Indigestion

• Flu-Like Symptoms

• How long is the duration of effect?

  The exact duration of effect of this medicine is not known. On an average, it is about 8 to 12 hours.

• What is the onset of action?

  The onset of action of this medicine is not known. However, reports have specified one day before onset of action.

• Is it habit forming?

  Habit forming tendencies have not been reported for this medicine.

• Is It safe with alcohol?

  If you take this medicine with alcohol, you will have a higher chance of stomach and gastrointestinal bleeding. This is caused due to chemical naproxen. Therefore, you are advised to strictly avoid alcohol when consuming this medicine.

• Are there any pregnancy warnings?

  While concrete results on human foetuses are yet not available, experiments on animal foetuses have shown less than safe results. Therefore, it is not advisable for pregnant women to use this unless indispensable, and that too with the advice of a doctor.

• Are there any breast-feeding warnings?

  Experiments on neither humans nor animals have been carried out, and data is not available. You should always consult your doctor before use of this medicine when lactating.

• Is it safe to drive while on this medicine?

  Do not engage in physically or mentally taxing activities like driving or operating heavy, complex machines while on this medicine.

• Does this affect kidney function?

  If you have kidney problems, you are advised to not use this medicine, especially if your condition is severe. If your kidneys are permanently destroyed, you have to avoid this medicine altogether.

• Does this affect liver function?

  This medicine does not harm ongoing liver treatment, and liver medication also does not interfere with its functioning. Therefore, you can use this medicine at the average dosage amount even if you have liver disease.

Below is the list of medicines, which have the same composition, strength and form as Napra D 500Mg Tablet , and hence can be used as its substitute.

• Naprodom 500Mg Tablet

  Crescent Therapeutics Ltd

• Naxdom 500 Tablet

  Sun Pharmaceutical Industries Ltd

• Pandex Tablet

  Mission Research Laboratories Pvt Ltd

• Are there any missed dose instructions?

  If you miss a dose, you should take another supplementary dose as fast as possible. However, do not take it very close to the time for your next dose, and do not take additional doses in amounts greater than specified for you.

• Are there any overdose instructions?

  If you suspect an overdose, make sure of your condition by checking for symptoms of an overdose. After that, contact your doctor or seek medical help immediately.

Napra D 500 MG Tablet is a combination of Naproxen and Domperidone. This medicine is prescribed for the treatment of migraine attacks. As both the drugs belong to two different classes, namely, NSAIDs (Non-Steroidal Anti Inflammatory Drug) and Dopamine antagonist, respectively, thus it works via dual mechanism.

Firstly it inhibits prostaglandin synthesis by non selectively impeding the COX -1 and COX -2 enzymes. This helps in alleviating inflammation, as prostaglandin is a regulator for inflammation in muscles. Secondly, it gets attached to the dopaminergic receptors without causing any release of the chemical dopamine. This, in turn, eases gastric emptying and abate small bowel transit time.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Alcohol use is strictly advised against when you are on this medicine. That is because alcohol increases the tendency of your stomach to bleed, which may be a side effect of this medicine. The bleeding is caused due to the chemical naproxen.

• Interaction with Medicine

  Napra D 500 MG Tablet may interact with other medicines you currently are on. These other medicines include antacids, aluminium hydroxide and oxide, amiodarone, amprenavir, aprepitant, atropine, bisoprolol, erythromycin, fluconazole and ketoconazole.

• Interaction with Disease

  Napra D 500 MG Tablet should not be consumed in case you have had allergy to it or its active components in the past. It also should not be taken in case you have other diseases like vertigo, active peptic ulcers, kidney diseases and impairment, gastrointestinal and stomach bleeding and congestive heart failure.

• Interaction with Food

  Napra D 500 MG Tablet does not have any known interactions with food items.

• Ques : What is Napra D 500Mg Tablet?

  Ans : Napra D 500Mg Tablet is a medication used to treat migraine. This medication contains domperidone and naproxen as active ingredients. Do not chew or break this medicine, it has to be swallowed as a whole and can be taken with or without food at a fixed time.

• Ques : What is Napra D 500Mg Tablet used for?

  Ans : This medication used to treat, control, and prevent condition such as Acute migraine attacks and Vomiting.

• Ques : What are the side effects of Napra D 500Mg Tablet?

  Ans : Napra D 500Mg Tablet has several side effects that can appear because of its ingredients which are domperidone and naproxen. Some of the side effects are mentioned below;

  • Drowsiness,
  • Headache,
  • Depression,
  • Itching,
  • Inability of concentration, and
  • Swelling of eyes and lips.

• Ques : Can Napra D 500Mg Tablet be used for acute migraine attacks and analgesic?

  Ans : Yes, this medication can be used to treat analgesic and intense migraine attacks. Do not consume Napra D 500 Tablet for analgesic and intense migraine attacks without asking your doctor first. It is a prescribed medication which should only be used on prescription only.

• Ques : How long do I need to use Napra D 500Mg Tablet before I see improvement of my conditions?

  Ans : In Most of the cases the average time taken by this medication, to reach its peak effect is within a day, before noticing improvement in the condition. But the same experience is not mandatory to everyone and so, it is not a recommended time period for this medication's action. Please consult your doctor, for the time period you need to consume this medication.

• Ques : At what frequency do I need to use Napra D 500Mg Tablet?

  Ans : Napra D 500 MG Tablet is generally used twice a day, as the time interval upto which this medication has an impact, is around 10 to 12 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor for the dosage, as the frequency also depends on the patient's condition.

• Ques : Should I use Napra D 500Mg Tablet empty stomach, before food or after food?

  Ans : The action of salts involved in this medication, do not depend on using it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

• Ques : What are the instructions for storage and disposal of Napra D 500Mg Tablet?

  Ans : Napra D 500 MG Tablet contains salts, which are suitable to store between 15 to 30 degree Celsius temperature and keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light.

• Naproxen 500 mg tablets- EMC [Internet]. www.medicines.org.uk. 2018 [Cited 23 April 2019]. Available from:

  https://www.medicines.org.uk/emc/product/543/smpc

• Naproxen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/naproxen

• Domperidone 10mg Tablets- EMC [Internet]. www.medicines.org.uk. 2018 [Cited 23 April 2019]. Available from:

  https://www.medicines.org.uk/emc/product/556