Neopride Total Capsule Sr

Neopride Total Capsule Sr is a combination medication, primarily used for treating ulcerative GERD. It is also prescribed for erosive healing, maintenance of ulcerative GERD, duodenal ulcers, irritable bowel syndrome and chronic gastritis. Recently, it has also come to be used in the treatment of hypersecretory conditions that include Zollinger-Ellison syndrome.

On using Neopride Total Capsule Sr the associated side effects that you may suffer from are disorientation, delirium, the elevation of thyroid-stimulating hormone (TSH), rhabdomyolysis, bullous, erythema multiforme, drug-induced diarrhoea, twitching, tremor, weight gain or akathisia.

In certain severe cases, you may experience jaundice, interstitial pneumonia, tardive dyskinesia, gynecomastia (a disorder of the endocrine system where there is an enlargement of the male breast size). In the latter case it will be necessary for you to seek medical attention.

Before using this medication it is advised that you consult your doctor and tell him/her if you had/have or are:

• Pregnant, or are planning to become pregnant.
• Nursing a baby
• Taking any prescriptive or over the counter drugs, herbals medications or dietary supplements.
• A recent surgery or are scheduled for one in the near future.
• Pheochromocytoma or gastrointestinal perforation.
• A history of cancer-related disease.
• A history of epilepsy or any other kind of seizures.
• Allergic to any medicine, food or substance.

The dosage of this medication will be as prescribed by your doctor as per the severity of your condition, your age, gender and overall medical history. But commonly a dose of 25 mg of this medicine is prescribed which needs to be taken three times in a day. Results may start to show within an hour or two of using. In case of drug overdose notify your physician right away.

• Gastroesophageal Reflux Disease

• Irritable Bowel Syndrome (Ibs)

• Duodenal Ulcer

• Allergy

• Epilepsy

• Bipolar Disorder

• Pheochromocytoma

• Breast Cancer

• Breast Tenderness

• Gynecomastia

• Weight Gain

• Unusual Tiredness And Weakness

• Decrease In Libido

• Fever

• Excessive Sweating

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 5-8 hours upon oral administration.

• What is the onset of action?

  The effect of this medicine can be observed within 1-2 hours of oral administration.

• Are there any pregnancy warnings?

  Use of this medicine during pregnancy is not recommended unless absolutely necessary. It is advised to use this medicine only when the benefits outweigh the risks involved.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  The medicine should not be consumed by breastfeeding mothers as there is a higher risk of side-effects on the infant. You are suggested to consult your doctor to discuss the potential benefits and risks before taking this medicine.

• Is it safe to drive while on this medicine?

  This medicine affects the consciousness of the patient, thus driving must be avoided while taking this medicine.

• Does this affect kidney function?

  Only limited information is available regarding its use in patients with kidney disease. Kindly consult your doctor before taking it.

• Does this affect liver function?

  Caution must be taken in patients with liver disease. Adjustment of dose is needed. Kindly consult your doctor before taking this medicine.

Below is the list of medicines, which have the same composition, strength and form as Neopride Total Capsule Sr , and hence can be used as its substitute.

• Cyra-Ls Tablet Sr

  Systopic Laboratories Pvt Ltd

• Acera L 75Mg/20Mg Tablet Sr

  Ipca Laboratories Ltd

• Zaxid-L 75Mg/20Mg Capsule Sr

  Akumentis Healthcare Ltd

• Derek L Capsule SR

  Albert David Ltd

• Rabifast-Xl Capsule

  Zuventus Healthcare Ltd

• Superia L Capsule Sr

  Sun Pharmaceutical Industries Ltd

• Happi-L Capsule Sr

  Zydus Cadila

• Drego Ls 75 Mg/20 Mg Capsule Sr

  USV Ltd

• Rabonik Plus Capsule SR

  Eris Life Sciences Pvt Ltd

• Rekool-L Tablet Sr

  Alembic Pharmaceuticals Ltd

• Are there any missed dose instructions?

  Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped.

• Are there any overdose instructions?

  Contact a doctor if an overdose with this medication is suspected. Symptoms of an overdose may include excessive drowsiness, fall in blood pressure, agitation, coma, etc.

This medicine is a combination of Levosulpiride and Rabeprazole. These two belongs to neuroleptic and PPI class respectively. Thus this medicine works via the dual mechanism.

Firstly, it works by selectively binding to dopamine receptors in the brain and the periphery. This action results in an increased tone of muscles in the gastrointestinal tract. Secondly, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Avoid or limit the uptake of alcohol while taking this medicine as the risk of adverse effects are increasingly high. Contact your doctor if an excess of drowsiness is experienced.

• Interaction with Others

  Pregabalin

  Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent monitoring while using these medicines together. Do not stop the use of any medicine without consulting your doctor.

• Interaction with Lab Test

  Prolactin test

  Report the use of this medicine before undergoing a laboratory test to determine the levels of the hormone prolactin in the body. This medicine can interfere with the test and yield false positive results.

• Interaction with Medicine

  Diltiazem

  Report the use of diltiazem or any other medicine taking for managing high blood pressure to the doctor. These medicines should be used with caution as the risk of adverse effects are increasingly high. Your doctor may determine the best course of treatment after assessing the conditions.

  Sucralfate

  Report the use of either of the medicine to the doctor. You may require a dose adjustment and frequent clinical monitoring while using these medicines together. Do not stop the use of any medicine without consulting your doctor.

  Tramadol

  Report the use of any narcotic pain-killer medicine to the doctor. These medicines should be used with extreme caution as the risk of adverse effects are significantly high. Your doctor may decide the best course of treatment after assessing the conditions.

  Aluminium Hydroxide/Magnesium Hydroxide

  Report the use of any aluminum or magnesium containing antacids to the doctor before receiving this medicine. You may need a dose adjustment and frequent clinical monitoring to safely use these medicines together.

  Ipratropium

  Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent monitoring while using these medicines together. Do not stop the use of any medicine without consulting your doctor.

  Warfarin

  Concomitant use of this medication with warfarin causes increase in INR and prothombin time. This leads to abnormal bleeding and even death.

  Cyclosporine

  If concomitantly administered, this medication inhibits the metabolism of cyclosporine and creates its concentration to be over 50 times higher than its normal Cmax.

  Other medications

  Its action on GI motility could also be antagonized by concomitant use of narcotics, anticholinergic agents and analgesics.

• Interaction with Disease

  Heart Diseases

  This medicine should be used with caution in patients suffering from a disease of the heart and blood vessels. You may require an adjusted dose and safety monitoring to safely use this medicine.

  Gastrointestinal Bleeding

  This medicine should be used with extreme caution in patients suffering from perforation and bleeding of the stomach and the intestine. Report any instance of fever with chills, nausea, vomiting, presence of blood in stool to the doctor.

  Prolactin Imbalance

  This medicine should not be used in patients having an abnormal level of the hormone prolactin. Breast cancer due to a high level of prolactin should be ruled out before treatment with this medicine is initiated.

  Neuroleptic Malignant Syndrome (Nms)

  Use of this medicine is not recommended if the patient suffers from Neuroleptic malignant syndrome. Introduction or reintroduction of this medicine should be done with caution in patients having a known history of this syndrome.

  Asthma

  This medicine should be used with caution if you have asthma. Report any instances of difficulty in breathing, wheezing, chest pain etc to the doctor immediately.

• Interaction with Food

  Information not available.

• Ques : What is Neopride Total Capsule Sr?

  Ans : This medicine is a combination of levosulpiride and rabeprazole. It is primarily used for the treatment of Gastroesophageal reflux disease and irritable bowel syndrome.

• Ques : What are the uses of Neopride Total Capsule Sr?

  Ans : It is prescribed for treating the following-

  • Healing of erosive or ulcerative gastro-oesophageal reflux disease (GERD)
  • Maintenance of healing of erosive or ulcerative GERD
  • Healing of duodenal ulcers
  • Treatment of pathological hypersecretory conditions, including Zollinger- Ellison syndrome
  • Irritable bowel syndrome
  • Chronic gastritis

• Ques : What are the Side Effects of Neopride Total Capsule Sr?

  Ans : This medication has many common side effects such as Nausea, Stomach pain, Diarrhea, Flatulence, Constipation, Headache, Dizziness, Weakness, Sleepiness, Flu-like symptoms. In case of patients having any of the side effects or issues like allergic reactions or skin rashes. It is advised to stop the consumption of this medicine and contact to doctor as soon as possible.

• Ques : What are the instructions for storage and disposal Neopride Total Capsule Sr?

  Ans : Store this capsule in a cool dry place and keep it in the original pack or container until it is time to take them. Store this medication out of sight and reach of children. Unused medicines should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

• Ques : How long do I need to use Neopride Total Capsule Sr before I see improvement of my conditions?

  Ans : Neopride Total Capsule Sr is a medicine which takes 1 or 2 days before you see an improvement in your health conditions. It would be ideal if you note, it doesn't mean you will begin to notice such health improvement in a similar time span as different patients. There are numerous elements to consider such as, salt interactions, precautions to be taken care of, time is taken by the salt to performs its action, etc.

• Ques : What are the contraindications to Neopride Total Capsule Sr?

  Ans : Contraindication to Neopride. In addition, this medication should not be used if you have the following conditions such as Allergic reactions, Breastfeeding, Cardiac impairment, Epilepsy, Gastrointestinal bleeding, Hyperprolactinaemia, Hypersensitivity, etc.

• Ques : Is Neopride Total Capsule Sr safe to use when pregnant?

  Ans : This medication is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

• Ques : Will Neopride Total Capsule Sr be more effective if taken in more than the recommended dose?

  Ans : No, taking higher than the recommended dose of this medication can lead to increased chances of side effects such as Allergic reactions, Breastfeeding, Cardiac impairment, Epilepsy, Gastrointestinal bleeding, etc.

• Levosulpiride- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 26 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/levosulpiride

• Gupta, S., Garg, G.R., Halder, S. and Sharma, K.K., 2007. Levosulpiride: a review. Delhi Psychiatry Journal, 10(2), pp.144-146 [Cited 23 May 2019]. Available from:

  http://medind.nic.in/daa/t07/i2/daat07i2p144.pdf

• Rabeprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/rn/117976-89-3

• Rabeprazole: Uses, Side Effects, Dosage- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 24 April 2019]. Available from:

  https://www.drugsbanks.com/important-information-about-rabeprazole/