Nervite 75mg/10mg Tablet

Nervite 75mg/10mg Tablet is a combination medication prescribed for the treatment of severe neuropathic pain. It is also used for the management of neuropathic disorders like diabetic peripheral neuropathy, postherpetic neuralgia, and spinal cord injury.

It works by binding to a certain region of the brain and reducing the pain signals sent out by the damaged nerves of the body. This medicine is also utilised for treating restless leg syndrome, epilepsy, shingles, seizures, fibromyalgia and generalised anxiety disorder.

This medication is not recommended for you if you are pregnant, or have an allergic reaction towards any of its ingredients. Some medicines interact with it. Inform your doctor if you are taking any of the following:

• Angiotensin- converting enzyme inhibitors
• Benzodiazepines or narcotic pain medicines
• Thiazolidinedione antidiabetic agents

Ensure your doctor is informed if you have any of the following medical conditions before starting the medication:

• If you have congestive heart failure, irregular heartbeat, diabetes, bleeding problems, muscle problems, highballed pressure or low platelet count.
• If you have improper kidney functioning or are on dialysis.
• If you have a history of angioedema.
• If you are pregnant, planning to be pregnant or are breastfeeding.
• If you take any other medicines, dietary supplements or herbal preparations.
• If you have mental or mood problems, suicidal thoughts, or are dealing with depression.

The dose for this medication may vary according to the age, sex, pathological conditions and other factors. The dosage can later be increased depending on efficacy and tolerability of the patient.

• Neuropathic Pain

• Diabetic Peripheral Neuropathy

• Postherpetic Neuralgia

• Allergy

• Myocardial Infarction

• Dizziness

• Drowsiness

• Peripheral Edema

• Nausea

• Blurred Vision

• Dry Mouth

• Weight Gain

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 10-12 hours.

• What is the onset of action?

  This medicine has a varying onset time depending on the intended use.

• Are there any pregnancy warnings?

  Use of this medicine during pregnancy is not recommended unless absolutely necessary.

• Is it habit forming?

  This medicine has a low abuse potential with limited physical and psychological dependence.

• Are there any breast-feeding warnings?

  Use of this medicine by breastfeeding women is not recommended.

Below is the list of medicines, which have the same composition, strength and form as Nervite 75mg/10mg Tablet , and hence can be used as its substitute.

• Pretyline 75Mg/10Mg Tablet

  Carise Pharmaceuticals Pvt Ltd

• Nuromark Pnt 75Mg/10Mg Tablet

  Unimarck Healthcare Ltd

• Pregalift Nt 75 Mg/10 Mg Tablet

  Linux Laboratories

• Pregamax Nt 75Mg/10Mg Tablet

  Winmark Pharmaceuticals Pvt Ltd

• Preganza Nt Tablet

  Emcure Pharmaceuticals Ltd

• Megabid Nt 75Mg/10Mg Tablet

  Ordain Health Care Global Pvt Ltd

• Gabacure Nt 75Mg/10Mg Tablet

  HBC Lifesciences Pvt Ltd

• Neurotin-Nt Tablet

  Medsol India Overseas Pvt Ltd

• NERVILAX NT 75MG/10MG TABLET

  Saffron Therapeutics Pvt Ltd

• Zylin Nt 75 Mg/10 Mg Tablet

  Zydus Cadila

• Missed Dose instructions

  Take the missed dose as soon as you remember.

• Are there any overdose instructions?

  Contact your doctor immediately if an overdose is suspected.

This medication is a combination of Pregabalin and Nortriptyline, thus work through a dual mechanism of action. Primarily, it behaves as a GABA analogue and binds to the voltage-gated calcium channels in the central nervous system. This causes a reduced release of neurotransmitters like serotonin, dopamine, substance P thus slowing down nerve signals. Secondarily, it blocks the serotonin reuptake at the neuronal membrane. Also, it inhibits the reuptake of norepinephrine and raises its concentration in the synaptic cleft.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Ethanol

  Avoid or limit the use of alcohol while taking this medicine.

• Interaction with Lab Test

  Lab

  Information not available.

• Interaction with Food

  Food

  Information not available.

• Ques : What is Nervite 75mg/10mg Tablet?

  Ans : This medication is a combination of Pregabalin and Nortriptyline and is considered to be the first-line of treatment for neurotic pain, shingles, seizures and fibromyalgia.

• Ques : How long do I need to use Nervite 75mg/10mg Tablet before I see improvement in my condition?

  Ans : This medication is to be taken till the time you see an improvement in your health conditions.

• Ques : What are the Side Effects of Nervite 75mg/10mg Tablet?

  Ans : Constipation, Difficulty in urination, Weight gain, Sleepiness, Dizziness, Tiredness, Blurred vision, Dryness in mouth, Increased heart rate, etc are possible side-effects which may occur.

• Ques : What are the instructions for storage and disposal Nervite 75mg/10mg Tablet?

  Ans : Nervite 75mg/10mg should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

• Ques : At what frequency do I need to use Nervite 75mg/10mg Tablet?

  Ans : This medication should be taken in the dosage as prescribed by the doctor.

• Nortriptyline- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 23 January 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/pregabalin

• Pregabalin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 23 January 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/nortriptyline

• Nortriptyline 10 mg Film-coated Tablets [Internet]. medicines.org.uk 2019 [Cited 23 January 2020]. Available from:

  https://www.medicines.org.uk/emc/medicine/32962