Nervite Plus Tablet

This is a combination medication which has Pregabalin, Nortriptyline, and Methylcobalamin as active ingredients. It is an anticonvulsant. This medication is considered to be the first-line of treatment for neurotic pain, shingles, seizures, and fibromyalgia. It is used for the treatment of diabetic nerve pain, epilepsy, spinal cord injury, restless leg syndrome, and generalized anxiety disorder. This works by binding to a certain region of the brain. Also, reducing the pain signals sent out by the damaged nerves of the body.

Some common side effects of this medication include sleepiness, trouble with memory, confusion, poor motor coordination, the problem with vision, dry mouth and weight gain. More serious side effects may include drug misuse, angioedema, and an increased risk of suicide. Prolonged use of this medicine can cause addiction.

The initial dose for this medication is usually 50 mg, taken orally 3 times a day. the dosage can later be increased depending on efficacy and tolerability.

• Neuropathic Pain

• Allergy

• Hypersensitivity

• Difficulty In Breathing

• Chest Tightness

• Chills

• Blurred Or Double Vision

• Allergic Skin Reaction

• Dizziness

• Dry Mouth

• How long is the duration of effect?

  The effect of this medication lasts for an average duration of 10-12 hours.

• What is the onset of action?

  This medication has a varying onset time depending on the intended use.

• Are there any pregnancy warnings?

  Use of this medication during pregnancy is not recommended unless absolutely necessary. It should be used only when no other alternatives are capable of producing the desired results. Consult your doctor and discuss the potential benefits and risks before taking this medicine.

• Is it habit forming?

  This medication has a low abuse potential with limited physical and psychological dependence.

• Are there any breast-feeding warnings?

  Use of this medication by breastfeeding women is not recommended. However, if it becomes necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before using this medicine.

• Missed Dose instructions

  Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose can be skipped.

• Are there any overdose instructions?

  Contact your doctor immediately if an overdose is suspected.

This medication is a GABA analog and binds to the voltage-gated calcium channels in the central nervous system. It causes a reduced release of neurotransmitters like serotonin, dopamine, substance P thus slowing down nerve signals. Nortriptyline is a tricyclic antidepressant which blocks the norepinephrine presynaptic receptors which in turn inhibits norepinephrine reuptake. This raises its concentration in the synaptic clefts of the CNS. It also blocks the reuptake of serotonin at the neuronal membrane. Methylcobalamin acts as a cofactor for enzyme methionine synthase, which transfers methyl groups for the regeneration of methionine from homocysteine. In anemia, it increases blood cell production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Ethanol

  Avoid or limit the use of alcohol while taking this medicine. One should refrain from operating heavy machinery or performing works that require a high level of mental alertness.

• Interaction with Lab Test

  Lab

  Information not available.

• Interaction with Medicine

  Lorazepam

  Report the use of Lorazepam or any other medicine that you take for sleep disorders or anxiety problems. The risk of adverse effects like dizziness, drowsiness, confusion, lack of focus, etc., is very high while taking these medicines together. Special precaution is advised if these medicines are taken by an elderly person.

  Pioglitazone

  Report the use of Pregabalin to the doctor before receiving Pioglitazone or any other medicine used for controlling high blood sugar levels. These medicines could increase the risk of weight gain, fluid retention, and heart failure when taken together. You may need a dose adjustment and frequent monitoring to safely use these medicines together.

  Ramipril

  Report the use of Ramipril or any other medicine belonging to the class of ACE inhibitors used for lowering blood pressure. The risk of fluid retention and associated adverse effects on the heart are significantly increased when these medicines are used together.

  Oxycodone

  Report the use of any opiate pain medicines to the doctor before receiving Pregabalin. Using these medicines together can cause severe dizziness, confusion, lack of coordination especially in the elderly and people with a history of emotional disturbances, suicidal thoughts, alcohol abuse, or drug abuse. Any such effect while using them together should be reported to the doctor.

• Interaction with Disease

  Angioedema

  This medicine should be administered with caution in patients who have a history of or are at risk of developing swellings of the inner layers of the skin. These swellings can cause airway blockage and prove life-threatening.

• Interaction with Food

  Food

  Information not available.

• Ques : What is nervite plus tablet?

  Ans : This medication has Pregabalin, Nortriptyline and Methylcobalamin as active elements present. Pregabalin reduces pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical, serotonin and noradrenaline that stop the movement of pain signals in the brain. Methylcobalamin is a form of vitamin B that helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells.

• Ques : What are the uses of nervite plus tablet?

  Ans : This medication is used for the treatment and prevention from conditions such as Neuropathic pain. The patient should inform the doctor about any ongoing medications and treatment before using Nervite plus tablet to avoid undesirable effects.

• Ques : What are the Side Effects of nervite plus tablet?

  Ans : This medication has some commonly reported side effects. Here are some side effects of this medication which are as follows: constipation, weight gain, orthostatic hypotension, increased heart rate, dizziness, sleepiness, tiredness, etc.

• Ques : What are the instructions for storage and disposal nervite plus tablet?

  Ans : Store this medication in a cool dry place and keep it in the original pack or container until it is time to take them. Store this medication out of sight and reach of children and pets.