Nexito Plus Tablet

Nexito Plus Tablet is used to treat and prevent generalized anxiety disorder and depression. This medicine is a combination of an anti-epileptic and an anti-convulsant in combination with an antidepressant. This medicine is administered to control panic attacks.

Belonging to a cluster of drugs called benzodiazepines. Nexito Plus Tablet works by inducing a calming effect on your nerves and brain. The most common side effects include

• drowsiness
• dizziness
• fatigue
• loss of focus
• increased secretion of saliva in the mouth.

Let your doctor know if you have been feeling depressed for no particular reason. If you notice any change in the way you behave with people around you. Other side effects include rash, itching, sore throat and fever.

This medication can increase suicidal thoughts and behaviours especially amongst teenagers, children, and young adults if taken in excess amounts. Hence, this drug should only be taken under a doctor’s prescription.

This medication is normally prescribed to be taken once a day. The usual dose is 10-20 mg for adults as well as children. It is not suitable for everyone as it might cause harmful effects on people suffering from certain conditions.

If you are suffering from irregular heartbeats or are allergic to certain ingredients present in the medicine, it is advisable to consult with the doctor first. Also, this medication might have a harmful effect on a pregnant woman. Consult with the doctor if you have a history of liver disease or kidney disease.

Take exactly as directed (do not increase dose or frequency); may cause physical and/or psychological dependence. While using this medication, do not use alcohol and other prescription or OTC medications (especially pain medications, sedatives, antihistamines, or hypnotics) without consulting prescriber.

• Anxiety Disorder

• Allergy

• Liver Disease

• Glaucoma

• Delayed Ejaculation

• Confusion

• Vomiting

• Memory Impairment

• Drowsiness

• Tiredness

• Diarrhoea

• Uncoordinated Body Movements

• How long is the duration of effect?

  The effect of this medication lasts for an average duration of 6 to 8 hours in adults. This duration increases to 12 hours in infants and children.

• What is the onset of action?

  The effect of this medication can be observed within 30 to 40 minutes of administration.

• Are there any pregnancy warnings?

  Pregnant women should consult doctor before using this medication.

• Is it habit forming?

  Habit forming tendencies were reported in some cases especially if the usage is for an extended period of time. A gradual withdrawal of the drug i.e. decrease in dosing over a period of time is suggested in such cases.

• Are there any breast-feeding warnings?

  The medicine should not be consumed by breastfeeding mothers as there is a higher risk of side-effects on the infant. You are suggested to consult your doctor to discuss the potential benefits and risks before taking this medicine.

• Is It safe with alcohol?

  It is unsafe to consume alcohol with this medicine. Kindly consult your doctor.

• Is it safe to drive while on this medicine?

  This medicine may cause side effects that affects the consciousness of the patient. Thus driving must be avoided while taking this medicine.

• Does this affect kidney function?

  This medicine is probably safe to be used in patients with kidney disease. Availability of limited data suggests that adjustment of dose might not be needed. Kindly consult your doctor before this medicine.

• Does this affect liver function?

  Caution must be taken in patients with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

Below is the list of medicines, which have the same composition, strength and form as Nexito Plus Tablet , and hence can be used as its substitute.

• Citajoy C 0.5 Mg/5 Mg Tablet

  Wings Biotech Ltd

• Xtaz 5Mg Tablet

  Medley Pharmaceuticals

• Es Ok Plus 0.5 Mg/5 Mg Tablet

  Eisai Pharmaceuticals India Pvt Ltd

• Clonasig Plus Tablet

  Signova Pharma Pvt Ltd

• S Citadep Plus 0.5 Mg/5 Mg Tablet

  Cipla Ltd

• Camdem 0.5Mg/5Mg Tablet

  Sinsan Pharmaceuticals

• Escirise Cz 0.5Mg/5Mg Tablet

  Carise Pharmaceuticals Pvt Ltd

• Escepam 0.5Mg/5Mg Tablet

  Carise Pharmaceuticals Pvt Ltd

• Joycom Plus 0.5 Mg/5 Mg Tablet

  Saffron Therapeutics Pvt Ltd

• Ezeepam Plus 0.5 Mg/5 Mg Tablet

  Eris Life Sciences Pvt Ltd

• Are there any missed dose instructions?

  Take the missed dose as soon as you remember. If it is time for the next scheduled dose then the missed dose can be skipped. Contact your doctor and seek advice if you there are any doubts regarding dosage.

• Are there any overdose instructions?

  Contact a doctor immediately if an overdose is suspected. Symptoms of an overdose like drowsiness, confusion or fainting should be reported immediately.

Nexito Plus Tablet is an anticonvulsant and an ant-epileptic which acts as a tranquilizer. It inhibits the synaptic transmission that occurs in the central nervous system. This also reduces the use of serotonin by neurons and is used to treat seizures and anxiety. Acts as a selective inhibitor of serotonin (5-HT) re-uptake with high affinity for the primary binding site. Binds to an allosteric site on the serotonin transporter, with a 1000 fold lower affinity.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Additive CNS depression has been reported with benzodiazepines; avoid or limit alcohol

• Interaction with Medicine

  • The combined use of Nexito Forte Tablet and valproic acid has been associated with absence seizures.
  • Carbamazepine, rifampin, rifabutin may enhance the metabolism of Nexito Forte Tablet and decrease its therapeutic effect; consider using an alternative sedative/hypnotic agent.
  • Cimetidine, ciprofloxacin, clarithromycin, clozapine, CNS depressants, diltiazem, disulfiram, digoxin, erythromycin, ethanol, fluconazole, fluoxetine, fluvoxamine, grapefruit juice, isoniazid, itraconazole, ketoconazole, labetalol, levodopa, loxapine, metoprolol, metronidazole, miconazole, nefazodone, omeprazole, phenytoin, rifabutin, rifampin, troleandomycin, verapamil may increase the serum level and/or toxicity of clonazepam; monitor for altered benzodiazepine response.

• Interaction with Disease

  This medication interacts with the following disease Seizure disorders, Closed-Angle Glaucoma, and Respiratory disorders.

• Ques : what is nexito plus tablet?

  Ans : Nexito Plus Tablet belongs to the antiepileptic and anticonvulsant class of medicines. It is used in treating and preventing seizures. It contains Clonazepam and Escitalopram as active ingredients. This medicine induces a calming effect on nerves and the brain. Nexito Plus Tablet works by increasing the activity of serotonin in the brain; enhancing the activity of gamma-aminobutyric acid (GABA) neurotransmitter.

• Ques : what is nexito plus tablet used for?

  Ans : Nexito Plus Tablet is used for the treatment and prevention from conditions and symptoms of diseases such as major depressive disorder, panic disorder, anxiety disorder, depression. Apart from these, it can also be used to treat a few other conditions. These include the treatment of seizure disorder, agitation, and even panic disorder. The patient should consult a doctor before using Nexito Plus Tablet for any of the above conditions about its dosage and side effects it may cause.

• Ques : what are the side effects for nexito plus tablet?

  Ans : This is a list of possible side-effects that may occur due to the constituting ingredients of Nexito Plus Tablet. This is an exhaustive list. These side-effects have been observed but do not always occur. Some of the side-effects may be rare but serious. These include constipation, drowsiness, insomnia, dry mouth, skin rash, and dizziness. Weight loss or gain, vertigo, headache, ejaculation disorder can also be included in the list of side effects of this medicine. If any of these symptoms occur often or on daily basis, a doctor should be promptly consulted.

• Ques : Can the Nexito Plus cause sleepiness or drowsiness?

  Ans : Yes, drowsiness is one of the side effects caused by the consumption of Nexito Plus Tablet. The patient should consult a doctor before taking this medication. The doctor should be informed about any ongoing medication or any allergies related to any of the constituents of this medicine. In case of any side effect occurs, the patient should not panic and report to some medical assistance.

• Ques : Can I take a higher than the recommended dose of this medicine?

  Ans : No, Nexito Plus is not adequate to take on higher dose as it may lead to severe side effects.

• Ques : Any special instruction regarding storage and disposal of Nexito Plus?

  Ans : Nexito Plus should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets. It is important to dispose unused medications and expired medications properly to avoid adverse effects.

• Ques : Can I stop taking Nexito Plus when my symptoms are relieved?

  Ans : No, Patient should not stop taking Nexito Plus immediately after symptoms are relieved. It may lead to adverse effects such as tiredness, headache, sleep changes and mood swings.

• Ques : what precaution should you take while using nexito plus tablet?

  Ans : Patients having allergic reactions, irregular heart beats, impaired renal functions, mania, porphyria and hypersalivation should not consume Nexito plus tablet.

• Clonazepam (Rivotril): Uses, Side Effects,Mechanism & Dosage- Drugs Bank [Internet]. drugsbanks.com. 2018 [Cited 26 April 2019]. Available from:

  https://www.drugsbanks.com/clonazepam-rivotril/

• Clonazepam- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 26 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/clonazepam

• Escitalopram- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 29 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/escitalopram