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Overview

Nexpro 40 MG Injection

Manufacturer :  Torrent Pharmaceuticals Ltd
Medicine Composition :  Esomeprazole
Prescription vs OTC : Prescription by Doctor required

About Nexpro 40 MG Injection

Nexpro 40 MG Injection is used in the treatment of conditions caused by excessive production of acid in the stomach. The conditions may include erosive esophagitis, gastroesophageal reflux disease (GERD), Helicobactor pylori infections and Zollinger-Ellison syndrome (tumours in the pancreas or in the upper part of the small intestine). Apart from that, Nexpro 40 MG Injection can also help in preventing stomach ulcer that is caused due to the consumption of nonsteroidal anti-inflammatory drugs (NSAID).The medication is available as a delayed-release capsule or in the form of a liquid suspension.

Belonging to the drug group of proton pump inhibitors, Nexpro 40 MG Injection blocks the proton pump in your stomach’s cells. When this proton pump gets blocked, there will be less production of acid in your stomach.

The dosage of Nexpro 40 MG Injection is decided by your doctor based on your age, the severity of the condition, your medical history and the reaction of your body after taking the first dose. Taking this medication can lead to certain mild side effects like headache, nausea, diarrhea, constipation, stomach pain, flatulence and dry mouth. In case of babies, the side effects may include burping up of food and an increase in the breathing rate. However, you must consult your doctor immediately if you suffer from serious side effects like:

  • Severe diarrhea with stomach pain, watery stool and fever
  • Inflammation of your stomach lining
  • Low magnesium levels, the symptoms of which include dizziness, seizures, tremors, muscle weakness, cramps or abnormal heart rates
  • An allergic reaction to the medication
  • Inflammation of the kidneys

It should be kept in mind that Nexpro 40 MG Injection is processed by the liver. If you have a chronic liver disease, the body will be unable to process it well, causing build-up of the drug. Also, this medicine can pass on to a child through his/her mother by breastfeeding. Hence, both pregnant and breastfeeding mothers must consult the doctor before taking the medication.

    What are the uses of Nexpro 40 MG Injection

    • Erosive Esophagitis

      Nexpro 40 MG Injection is used to cure severe ulcers caused from chronic acidity.

    • Gastroesophageal Reflux Disease

      Nexpro 40 MG Injection helps in Gastroesophagal Reflux Disease in which acid from the stomach and bile irritates the food pipe.

    • Helicobacter Pylori Infection

      Nexpro 40 MG Injection is also helpful against Helicobacter Pylori infection.

    • Zollinger-Ellison Syndrome

      Nexpro 40 MG Injection cures Zollinger-Ellison Syndrome, a condition where excessive amount of acid is produced in the stomach due to tumors in the small intestine.

    • Other Forms Of Ulcers

      Nexpro 40 MG Injection helps in curing ulcers in the stomach or small intestine. It can also be used to manage ulcers caused due from stress and pain medications.

    What are the contraindications of Nexpro 40 MG Injection ?

    • Allergy

      This medicine is not advised in patients who are allergic to it or any other drug of the same group.

    What are the side effects of Nexpro 40 MG Injection ?

    • Headache

    • Nausea

    • Flatulence

    • Stomach Pain

    • Skin Rash

    • Swelling And Redness At The Injection Site

    • Difficulty In Breathing

    • Swelling Of Face, Lips, Eyelids, Tongue, Hands And Feet

    • Irregular Heart Beat

    • Severe Diarrhea

    • Unusual Tiredness And Weakness

    • Fever

    • Decreased Appetite

    Key highlights of Nexpro 40 MG Injection

    • How long is the duration of effect?

      The effect of this medicine lasts for a duration of about 16-18 hours.

    • What is the onset of action?

      The effect of this medicine is usually observed in 1 hour of administration.

    • Are there any pregnancy warnings?

      This medicine cannot be used by pregnant women. Consult your doctor before taking this medicine.

    • Is it habit forming?

      No habit forming tendencies has been reported.

    • Are there any breast-feeding warnings?

      This medicine is not advised for use by breastfeeding women as it may cause certain side effects in the infant. Consult your doctor before taking this medicine.

    What are the substitutes for Nexpro 40 MG Injection ?

    Below is the list of medicines, which have the same composition, strength and form as Nexpro 40 MG Injection , and hence can be used as its substitute.

    What are the dosage instructions?

    • Missed Dose instructions

      Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose should be skipped.

    • Are there any overdose instructions?

      Contact your doctor immediately if an overdose is suspected. Symptoms may include confusion, drowsiness, blurred vision, dry mouth, and headache.

    How does this medication work?

    Nexpro 40 MG Injection is a proton pump inhibitor drug and binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

      What are the interactions of Nexpro 40 MG Injection ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Neuroendocrine tumor diagnosis

        Report the use of Nexpro 40 MG Injection to the doctor before undergoing for the neuroendocrine/carcinoid tumor test. This medicine may give a false positive result for this diagnostic test.
      • Interaction with Medicine

        Clopidogrel

        Report the use of either of the medicine to the doctor. Your doctor may prescribe a safer alternative for reducing the stomach acidity while you are being treated with Clopidogrel.

        Ketoconazole

        Nexpro 40 MG Injection should be used with Ketoconazole or other antifungals of the same group with caution. Inform the doctor about the usage of either of these medications so that safer alternatives can be prescribed.

        Methotrexate

        Nexpro 40 MG Injection should not be used with Methotrexate. Use of either of the drugs should be reported to the doctor so that safer substitute could be prescribed.

        Warfarin

        Usage of Nexpro 40 MG Injection with Warfarin should be strictly monitored by the doctor. Suitable adjustment in dosage and monitoring of Prothrombin time is necessary to ensure safety. Any symptoms like unusual bleeding, swelling, vomiting, or presence of blood in urine should be reported immediately.

        Nelfinavir

        Nexpro 40 MG Injection is not recommended for use when the patient is already taking anti-viral medications like Nelfinavir or other drugs used in the management of HIV Infection.

        Digoxin

        Nexpro 40 MG Injection should be used with caution if the patient is on Digoxin. Prior usage of any of these drugs should be informed to the doctor. Any symptoms like nausea, vomiting, diarrhea, loss of appetite, disturbances in vision, and abnormalities in heartbeat should be reported immediately.
      • Interaction with Disease

        Liver Disease

        Report any incidence of liver disease to the doctor. Suitable adjustment in dosage might be needed based on the extent of the liver impairment

        Osteoporosis

        Suitable adjustment in dosage and duration should be made for patients who are at risk for Osteoporosis related fracture. Established treatment guidelines should be strictly followed in such cases.

        Hypomagnesemia

        Report any incidence of magnesium level imbalance in the body to the doctor. The imbalance could occur due to a disease or due to other medication used by the patient. Regular monitoring is recommended for patients taking Nexpro 40 MG Injection in such cases.
      • Interaction with Food

        Food

        Information not available.
      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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