Nicorandil

Nicorandil is a vasodilatory drug. It treats angina chest pain. This medication widens blood vessels thus increasing the blood and oxygen flow to the heart. This medication is used to treat other heart conditions also.

On using Nicorandil you may experience side effects such as rapid or irregular heartbeat, swelling, darkening of urine, dizziness, headache, nausea, fatigue, a decrease in blood pressure levels, flushes, skin rash, high potassium levels, muscle pain or stomach pain. Notify your physician if you face any of these effects.

Before using this medication tell your doctor if you are allergic to any of the ingredients contained within Nicorandil, having any other allergies, already taking any medications, have low blood pressure, skin/ mouth ulcers, heart problems or pulmonary oedema, are pregnant or are breastfeeding a baby.

The dosage should be prescribed by your doctor based on your medical history and current condition. The usual dose in adults is about 10 mg twice a day which may be increased to 20 mg depending on your response.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Chest Pain

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Hypersensitivity

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Nausea

• Vomiting

• Headache

• Weakness

• Dizziness

• Flushing

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Is It safe with alcohol?

  It is unsafe to consume alcohol while taking this medicine.

• Are there any pregnancy warnings?

  Nicorandil may be unsafe to use during pregnancy.
  Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Are there any breast-feeding warnings?

  Nicorandil is probably unsafe to use during breastfeeding. Please consult your doctor.

• Does this affect kidney function?

  There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

• Is it safe to drive while on this medicine?

  This medicine might affect the consciousness of the patient. Thus driving must be avoided while taking Nicorandil.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Are there any missed dose instructions?

  If you miss a dose of Nicorandil, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

Below is the list of medicines, which contains Nicorandil as ingredient

• Zynicor 5Mg Tablet

  Zydus Cadila

• Corflo 5Mg Tablet

  Wockhardt Ltd

• Mayonil 5Mg Tablet

  El-Dorado Bio-Tech Pvt Ltd

• Nikosol 10Mg Tablet

  Saaol Pharma Pvt Ltd

• Nucoril 10Mg Tablet

  Emcure Pharmaceuticals Ltd

• K-Ion 5Mg Tablet

  Nouveau Medicament Pvt Ltd

• K-Ion 10Mg Tablet

  Nouveau Medicament Pvt Ltd

• Nicoduce Od 10Mg Tablet

  Abbott India Ltd

• Nicorex 20Mg Tablet

  Aprica Pharmaceuticals Pvt Ltd

• Nikoran 2Mg Injection

  Torrent Pharmaceuticals Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

This medication works following the dual mechanism. Firstly, it activates the ATP sensitive potassium channel, leading to vascular smooth muscle hyperpolarization. Secondly, it triggers guanylate cyclase to enhance the production of cyclic GMP, thereby activating protein kinase G. Therefore, GTPase RhoA is inhibited and Rho-kinase activity is decreased. As a result, the myosin phosphatase activity is accelerated and the calcium sensitivity of the smooth muscle is reduced. Owing to its nitrate property, nicorandil works as a vasodilator.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Medicine

  This medication interacts with Corticosteroids, Riociguat, NSAIDs, Phosphodiesterase 5 (PDE) inhibitors, and Vasodilators.

• Interaction with Disease

  This medication interacts with Gastrointestinal Disorders.

• Ques : What is Nicorandil?

  Ans : AnsNicorandil is a vasodilatory drug. It treats angina chest pain. This medication widens blood vessels thus increasing the blood and oxygen flow to the heart.

• Ques : What are the uses of Nicorandil?

  Ans : Ans Nicorandil is used for the control and treatment of Chest Pain.

• Ques : What are the side effects of this Nicorandil?

  Ans : On using Nicorandil you may experience side effects such as rapid or irregular heartbeat, swelling, darkening of urine, dizziness, headache, nausea, fatigue, a decrease in blood pressure.

• Ques : How long do I need to use Nicorandil before I see improvement in my condition?

  Ans : This medication is to be taken till the time you see an improvement in your health conditions.

• Ques : At what frequency do I need to use Nicorandil?

  Ans : This medication should be taken in the dosage as prescribed by the doctor.

• Ques : Should I use Nicorandil empty stomach, before food or after food?

  Ans : This medication should be taken after food in a prescribed dosage.

• Ques : What are the instructions for the storage and disposal of Nicorandil?

  Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

• Ques : How is this Nicorandil administered?

  Ans : This medication is administered orally.

• Nicorandil-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 14 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/nicorandil

• Nicorandil-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 14 June 2022].Available from:

  https://go.drugbank.com/drugs/DB09220