Niftran 100 MG Capsule
About Niftran 100 MG Capsule
Niftran 100 MG Capsule is administered to cure UTIs caused by a few typical kinds of bacteria. Lung inflammation is one of the major but very rare side effects of Niftran 100 MG Capsule and usually occurs if the usage persists for more than half a year.
Damage to the liver is also another serious but infrequent adverse reaction of Niftran 100 MG Capsule. If the therapy is a long term one, then certain tests will be administered to check whether all is good with liver functioning or not. Signs of liver damage include persistent itching, yellowing of the eye’s whites or the skin, vomiting, dark colored urine, nausea and reduced appetite.
Niftran 100 MG Capsule can also result in damage to the nerves. Nerve damage is characterized by pain and numbness of the feet and the hands. Another adverse effect of Niftran 100 MG Capsule is damage to the red blood cells. This condition is known as hemolysis, indicators of which include weakness, fatigue, tiredness and paling of the skin. This generally subsides once the usage is discontinued.
There are certain medications, administration of which is strictly advised against while using Niftran 100 MG Capsule. These include antacids that contain certain ingredients such as magnesium trisilicate, sulfinpyrazone and probenecid.
Pregnant women who are in their term of pregnancy (38 to 42 weeks) should talk to their doctor before using this drug. Also, Niftran 100 MG Capsule is usually advised against at the time of labor and delivery. This drug can be passed onto a mother’s breast milk and thus prove harmful for the baby that is being breastfed.
In case of the elderly, their kidney functioning isn’t usually at their best. Hence, any medicine, once inside their system, tends to stay there for a longer time, thus increasing the risks of various side effects.
Take per recommended schedule, at regular intervals around-the-clock. Complete full course of therapy; do not skip doses. Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake).
Diabetics should consult prescriber if using Clinitest® for glucose testing. Nitrofurantoin may discolor urine dark yellow or brown (normal). Use caution when driving or engaging in tasks that require alertness until response to drug is known.
Report chest pains or palpitations; pain on urination or blood in urine; skin rash; muscle weakness, pain, or tremors; excessive fatigue or weakness; other persistent adverse effects; or if condition does not improve.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.
What are the uses of Niftran 100 MG Capsule
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.
What are the contraindications of Niftran 100 MG Capsule ?
Impaired Kidney Function
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.
What are the side effects of Niftran 100 MG Capsule ?
Chills
Headache
Rash
Stomach Upset
Loss Of Appetite
Weakness
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.
Key highlights of Niftran 100 MG Capsule
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 1 to 3 hours.
What is the onset of action?
This medicine is well observed orally. Food may increase the bioavailability of the medicine.
Are there any pregnancy warnings?
This medicine is recommended for pregnant women. It is contraindicated in pregnant patients at term (38 to 42 weeks' gestation), during labor and delivery.
Is it habit forming?
No habit forming tendencies were reported
Are there any breast-feeding warnings?
This medicine is known to excreted through breast milk. This medicine is not contraindicated in children less than 3 months and glucose-6-phosphate dehydrogenase (G-6-PD) deficient infants.
Is It safe with alcohol?
Avoid consuming alcohol while taking this medicine.
Is it safe to drive while on this medicine?
This medicine might cause side effects that affect the alertness of the patient. Thus driving must be avoided.
Does this affect kidney function?
This medicine might be avoided in patients with Clcr <50 mL/minute. Also avoid use in hemo and peritoneal dialysis and continuous arteriovenous or venovenous hemofiltration (CAVH/CAVHD).
Does this affect liver function?
This medicine is probably safe to be used in patient with liver disease. Adjustment of dose might not be needed. Kindly consult for further details.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.
What are the substitutes for Niftran 100 MG Capsule ?
Below is the list of medicines, which have the same composition, strength and form as Niftran 100 MG Capsule , and hence can be used as its substitute.
- Macfuran 100 MG Capsule
Macleods Pharmaceuticals Pvt.Ltd
- Niftran Tm 100 MG Capsule
Ranbaxy Laboratories Ltd
- Nitrobact 100 MG Capsule
Mankind Pharmaceuticals Ltd
- U Free 100 MG Capsule
Zydus Cadila
- Urifast Cp 100 MG Capsule
Cipla Ltd
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.
What are the dosage instructions?
Missed Dose instructions
If you miss a dose of Niftran 100 MG Capsule, take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Are there any overdose instructions?
Seek emergency medical treatment or contact the doctor in case of an overdose.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.
Where is the Niftran 100 MG Capsule approved?
India
United States
Japan
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.
How does this medication work?
The active constituent of this medication belongs to the class urinary anti-infectives. It works by inhibiting the cell wall synthesis by forming reactive intermediates by bacterial flavoproteins. These intermediates will alter the bacterial ribosomal proteins, DNA synthesis, RNA synthesis and cell wall synthesis.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.
What are the interactions of Niftran 100 MG Capsule ?
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
- test
Interaction with Alcohol
Interaction with Lab Test
Interaction with Medicine
- Decreased effect: Antacids, especially magnesium salts, decrease absorption of nitrofurantoin; nitrofurantoin may antagonize effects of norfloxacin.
- Increased toxicity: Probenecid (decreases renal excretion of nitrofurantoin); anticholinergic drugs increase absorption of nitrofurantoin.
Interaction with Food
Interaction with Disease
- Use with caution in patients with G-6-PD deficiency, patients with anemia, vitamin B deficiency, diabetes mellitus or electrolyte abnormalities.
- Therapeutic concentrations of nitrofurantoin are not attained in urine of patients with Clcr <40 mL/minute (elderly).
- Use with caution if prolonged therapy is anticipated due to possible pulmonary toxicity.
- Acute, subacute, or chronic (usually after 6 months of therapy) pulmonary reactions have been observed in patients treated with nitrofurantoin.
- If these occur, discontinue therapy; monitor closely for:
- Malaise,
- Dyspnea,
- Cough,
- Fever,
- Radiologic evidence of diffuse interstitial pneumonitis or fibrosis.
FAQs about Niftran 100 MG Capsule
Ques : What is Niftran 100 MG Capsule?
Ans : Niftran 100 MG Capsule is administered to cure UTIs caused by a few typical kinds of bacteria. Lung inflammation is one of the major but very rare side effects of Niftran 100 MG Capsule and usually occurs if the usage persists for more than half a year.
Ques : What are the uses of Niftran 100 MG Capsule?
Ans : Niftran 100 MG Capsule used for the treatment of Urinary Tract Infection.
Ques : What are the side effect of this Niftran 100 MG Capsule?
Ans : Possible side effects of this tablet are as follows:
- Chest Pain
- Chills
- Fever
- Fatigue
- Drowsiness
Ques : How long do I need to use Niftran 100 MG Capsule before I see improvement in my condition?
Ans : This medication is to be taken till the time you see an improvement in your health conditions.
Ques : At what frequency do I need to use Niftran 100 MG Capsule?
Ans : This medication should be taken in the dosage as prescribed by the doctor.
Ques : Should I use Niftran 100 MG Capsule empty stomach, before food or after food?
Ans : This medication should be taken after food in a prescribed dosage.
Ques : What are the instructions for the storage and disposal of Niftran 100 MG Capsule?
Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.
Ques : How is this Niftran 100 MG Capsule administered?
Ans : This medication is administered orally.
References
Nitrofurantoin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:
https://druginfo.nlm.nih.gov/drugportal/name/nitrofurantoin
Nitrofurantoin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:
https://go.drugbank.com/drugs/DB00698
NITROFURANTOIN tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:
https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=NITROFURANTOIN
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Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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