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Overview

Nor Metrogyl Plus 500 Mg/200 Mg Tablet

Banned
Manufacturer :  LEKAR PHARMA LTD.
Medicine Composition :  Ofloxacin, Ornidazole
Prescription vs OTC : Prescription by Doctor not required

About Nor Metrogyl Plus 500 Mg/200 Mg Tablet

Nor Metrogyl Plus 500 Mg/200 Mg Tablet is a combination medication primarily prescribed for treating diarrhoea and/or dysentery. It comprises antibacterial and antiamoebic drugs that fight against parasitic and bacterial infections. It is very effective in treating infectious conditions due to its dual-action.

This medication inhibits the production of certain enzymes in the DNA of a bacteria, which are necessary for the survival and growth of this bacterial infections. Therefore, this antibiotic drug fights against bacterial infections by killing the bacteria and inhibiting the process of bacterial cell division.

It is advisable to take this medication only under the strict guidelines of your doctor. Follow this prescription until the course is complete, even if the symptoms disappear. You should not skip a dose and avoid taking an extra tablet to make up for it.

It is possible for some people to experience a few common side effects after taking this medication. Some people are more likely to face harmful side effects if they also suffer from other conditions like brain disorders, seizures, heart conditions, myasthenia gravis, epilepsy, tendonitis, bone disorders and problems of the joints.

It is advisable to inform your doctor about the above-mentioned conditions beforehand if he/she recommends you taking this medicine. It is advisable for pregnant women, women who are breastfeeding and children below 16 years, to avoid taking this antibiotic since it can lead to harmful consequences.

    What are the uses of Nor Metrogyl Plus 500 Mg/200 Mg Tablet

    • Infectious Diarrhea

    • Dysentery

    What are the contraindications of Nor Metrogyl Plus 500 Mg/200 Mg Tablet ?

    What are the side effects of Nor Metrogyl Plus 500 Mg/200 Mg Tablet ?

    • Abdominal Pain

    • Joint Pain

    • Fever With Chills

    • Numbness Of The Hands

    • Running Nose

    • Loss Of Appetite

    • Dizziness

    • Headache

    • Memory Impairment

    • Nervousness

    • Agitation

    • Disorientation

    Key highlights of Nor Metrogyl Plus 500 Mg/200 Mg Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for a duration of 12 to 20 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed within 1 to 2 hours of administration of the dose.

    • Are there any pregnancy warnings?

      Use of this medicine is not recommended in pregnant women. Use only if clearly needed under the supervision of the doctor.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      This medicine should be given to the breastfeeding women only if extremely needed. It is advised to consult the doctor before giving the medicine.

    • Is It safe with alcohol?

      This medication is not safe with alcohol. If you experience certain symptoms such as drowsiness or disorientation, then you must speak to your doctor immediately.

    • Is it safe to drive while on this medicine?

      As some of the side effects of this medication include headaches and hallucinations, it is not advisable to drive after taking the medication.

    • Does this affect kidney function?

      Patients who have impaired kidney function should not take this medication as it can lead to more kidney problems.

    • Does this affect liver function?

      Patients who have impaired liver function should not take this medication as it can lead to more liver problems, including liver failure.

    What are the substitutes for Nor Metrogyl Plus 500 Mg/200 Mg Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Nor Metrogyl Plus 500 Mg/200 Mg Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Contact the doctor in case of overdose.

    How does this medication work?

    This medicine is a combination of Ofloxacin and Ornidazole belonging to the class antibacterial and antiamoebic. Thus the medication follows a dual mechanism to produce its action. Firstly, it works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death. Secondly, it works by seeping into the cells of the bacteria and/or protozoa through diffusion and damaging DNA and other critical biomolecules through the formation of reactive nitro radicals.

      What are the interactions of Nor Metrogyl Plus 500 Mg/200 Mg Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        These tablets can have adverse interactions with certain medications. These include cholera vaccine, amikacin, Furosemide, ethinyl estradiol, warfarin, chloramphenicol, and nifedipine.
      • Interaction with Disease

        It can have negative interactions with certain diseases. These include heart disease, tendonitis, epilepsy impaired kidney function, and impaired liver function.

      FAQs about Nor Metrogyl Plus 500 Mg/200 Mg Tablet

      • Ques : What is Nor Metrogyl Plus 500 Mg/200 Mg Tablet?

        Ans : Nor metrogyl tablet is a medication which has Ofloxacin and Ornidazole as active elements present in it. This tablet performs its action by inhibits the infections caused by bacteria and restricts the growth of microorganism.

      • Ques : What are the uses of Nor Metrogyl Plus 500 Mg/200 Mg Tablet?

        Ans : It is a medication, which is used for the treatment of infectious diarrhoea and dysentery.

      • Ques : What are the Side Effects of Nor Metrogyl Plus 500 Mg/200 Mg Tablet?

        Ans : Side effects include Headache, Diarrhea, Photosensitivity, Nausea, Hallucination, Sinus tachycardia, Insomnia, Seizures, Dizziness, Vomiting, Severe, itching of the skin, Abdominal pain, Eosinophilia, Vaginitis, Distortion of the sense of taste, Tendon damage, Rupture, and Loss of app. It is a list of possible side-effects which may occur due to the constituting ingredients of this medication.

      • Ques : What are the instructions for storage and disposal nor Nor Metrogyl Plus 500 Mg/200 Mg Tablet?

        Ans : Store Nor metrogyl plus tablet in a cool dry place and keep it in the original pack or container until it is time to take them. Store this medication out of sight and reach of children.

      • Ques : How long do I need to use Nor Metrogyl Plus 500 Mg/200 Mg Tablet before I see improvement of my conditions?

        Ans : Nor Metrogyl Plus 500 Mg/200 Mg Tablet is a medicine which takes 1 or 2 days before you see an improvement in your health conditions.

      • Ques : What are the contraindications to Nor Metrogyl Plus 500 Mg/200 Mg Tablet?

        Ans : This medication should not be used if you have the conditions such as fever, rash, inflammation of the blood vessels, joint pain, muscle pain, inflammation of lungs, forming kidney diseases, acute kidney failure, etc.

      • Ques : Is Nor Metrogyl Plus 500 Mg/200 Mg Tablet safe to use when pregnant?

        Ans : This medication is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

      • Ques : Will Nor Metrogyl Plus 500 Mg/200 Mg Tablet be more effective if taken in more than the recommended dose?

        Ans : No, taking higher than the recommended dose of this medication can lead to increased chances of side effects such as diarrhea, dizziness, external genital severe itching, headache, inflammation of vagina, insomnia, nausea, Vomiting, etc.

      References

      • Ofloxacin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 24 January 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ofloxacin

      • Ornidazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 24 January 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ornidazole

      • Ofloxacin- DrugBank [Internet]. Drugbank.ca. 2020 [Cited 24 January 2020]. Available from:

        https://www.drugbank.ca/drugs/DB01165

      • Ornidazole- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 24 January 2020]. Available from:

        https://www.drugbank.ca/drugs/DB13026

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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