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Overview

Norflox Tz Lb 400 Mg/600 Mg Tablet

Manufacturer :  Cipla Ltd
Medicine Composition :  Norfloxacin, Tinidazole
Prescription vs OTC : Prescription by Doctor not required

About Norflox Tz Lb 400 Mg/600 Mg Tablet

Norflox Tz Lb 400 Mg/600 Mg Tablet is a combination medicine that is used to cure bacterial infections. It is primarily used to treat diarrhoea and dysentery. It is a combination of two antibiotics Norfloxacin and Tinidazole.

However, remember that this drug will not be effective for infections that aren’t caused by bacteria (viral infections such as common cold and the flu). Using an antibiotic repetitively and for infections that aren’t bacterial will lead the medicine to lose its potency over a period of time.

The treatment plan and dosage will depend upon the severity of the condition. It is advised to take this drug minimum two hours prior to consuming other minerals/vitamins or such products containing aluminium/magnesium such as antacids.

For best results, take this medicine at regular intervals every day. Try to limit your intake of caffeinated beverages such as coffee or tea, for that matter, as caffeine can interfere with the medicine’s potency in all probability. Don’t consume any dairy product either two hours prior to or an hour after taking this medication.

Risk factors for this medicine include kidney disorders, heart afflictions and epileptic seizures. It isn’t recommended for children below the age of 12 years. Overdosing on this medicine can result in irregular (slow) heartbeats.

Few side effects include an allergic response in the form of rashes, irritation of the skin, itching, etc. (though very rare), chest pain, dizziness, confusion, seizures, liver damage, joint or muscle pain, a ringing sensation in the ears (tinnitus), lightheadedness, diarrhea, fatigue, nausea, headaches and troubled sleeping.

Don’t take narcotic pain medicines if you experience any of these side effects since these can cause you more harm than good. Yeast infection and oral thrush are other concerns that might show up if you use this medicine indiscriminately. Know from your doctor the names of all those drugs that could diminish the efficacy of this medication.

    What are the uses of Norflox Tz Lb 400 Mg/600 Mg Tablet

    What are the contraindications of Norflox Tz Lb 400 Mg/600 Mg Tablet ?

    • Allergy

      Avoid taking Norflox Tz Lb 400 Mg/600 Mg Tablet if you have a known allergy to this medicine or any other medicines belonging to the class fluoroquinolones.

    • Tendinitis Or Tendon Rupture

      Avoid taking this medicine if you have a past history of tendinitis or tendon rupture after using Norflox Tz Lb 400 Mg/600 Mg Tablet.

    • Myasthenia Gravis

      Avoid taking this medicine if you have a past or family history of Myasthenia Gravis (weakness and rapid fatigue of muscles under voluntary control).

    What are the side effects of Norflox Tz Lb 400 Mg/600 Mg Tablet ?

    Key highlights of Norflox Tz Lb 400 Mg/600 Mg Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 9 to 12 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed in 1 to 2 hours.

    • Are there any pregnancy warnings?

      The medicine should not be consumed by breastfeeding mothers as there is a higher risk of side-effects on the infant. You are suggested to consult your doctor to discuss the potential benefits and risks before taking this medicine.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      Use of this medicine is not recommended in women who breastfeed due to the adverse effect on the development of the infant's joints. Use only if clearly needed under the supervision of the doctor. Monitoring of undesired effects like diarrhea, diaper rash is necessary.

    What are the substitutes for Norflox Tz Lb 400 Mg/600 Mg Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Norflox Tz Lb 400 Mg/600 Mg Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    How does this medication work?

    This medicine is a combination of Norfloxacin and Tinidazole. These drugs are antibiotic and belong to fluoroquinolone and anthelmintics, respectively. Thus it works following a dual mechanism.

    Firstly, it works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death.

    Secondly, it enters into the organism and forms the free radical. A concentration gradient is created in the organism due to alteration in the molecule and promotes the influx of the molecule. Thus, the free radical and the altered molecule will interfere with the DNA synthesis and stops the growth of the organism.

      FAQs about Norflox Tz Lb 400 Mg/600 Mg Tablet

      • Ques : What is Norflox Tz Lb 400 Mg/600 Mg Tablet?

        Ans : This medication belongs to the antibacterial group of medicines and is mainly used to cure bacterial infections. It contains Norfloxacin and Tinidazole as active ingredients. Norflox TZ LB Tablet works by inhibiting bacterial reproduction; killing bacteria and reducing the infection.

      • Ques : What is the use of Norflox Tz Lb 400 Mg/600 Mg Tablet?

        Ans : Norflox TZ LB 400 Mg/600 Mg Tablet is used for the treatment and prevention from conditions and symptoms of diseases like stomach infection, skin infection, vaginal infection, Infections of the abdomen, sexual dysfunction, and chest infections. Besides these, it can further be used to treat conditions such as urinary tract infections, sexually transmitted disease, typhoid fever, bacterial infections. The patient should inform the doctor about any ongoing medications and treatment before using Norflox TZ LB 400 Mg/600 Mg Tablet to avoid undesirable effects.

      • Ques : What are the side effects of Norflox Tz Lb 400 Mg/600 Mg Tablet?

        Ans : This is a list of possible side-effects which may occur due to the constituting ingredients of Norflox TZ LB 400 Mg/600 Mg Tablet. This is not a comprehensive list. These side-effects have been observed and not necessarily occur. Some of these side-effects may be serious. These include face redness, blurred vision, indigestion, nausea, abdominal swelling, and anal or rectal pain. Apart from these, using this medicine may further lead to conditions like abdominal pain, chills, abnormal blood counts, and vomiting. If any of these symptoms occur often or on daily basis, a doctor should be urgently consulted.

      • Ques : What are the instructions for storage and disposal of Norflox Tz Lb 400 Mg/600 Mg Tablet?

        Ans : Norflox TZ LB 400 Mg/600 Mg Tablet should be stored at room temperature, away from heat and direct light. Unless instructed by the package to do so, don’t freeze it. Keep it away from children and pets. Regarding the dosage of Norflox TZ LB 400 Mg/600 Mg Tablet, it should be consulted by a physician or pharmacist. You can also refer to the product package. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.

      • Ques : How long do I need to use Norflox Tz Lb 400 Mg/600 Mg Tablet before I see improvement in my condition?

        Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition. So please consult your doctor.

      • Ques : At what frequency do I need to use Norflox Tz Lb 400 Mg/600 Mg Tablet?

        Ans : The duration of effect for this medicine is dependent on the severity of the patient’s condition. Therefore the frequency of usage of this medication will vary from person to person. It is advised to follow the proper prescription of the doctor, directed according to the patient's condition.

      • Ques : Should I use Norflox Tz Lb 400 Mg/600 Mg Tablet empty stomach, before food or after food?

        Ans : This medication is advised to be consumed orally. The salts involved in this medication react properly if it is taken with the food. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

      References

      • Norfloxacin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/norfloxacin

      • Norfloxacin- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 1 February 2020]. Available from:

        https://www.drugbank.ca/drugs/DB01059

      • Tinidazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/tinidazole

      • Tinidazole- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 1 February 2020]. Available from:

        https://www.drugbank.ca/drugs/DB00911

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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