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Overview

Nortee 400mg Tablet

Manufacturer :  Zydus Cadila
Medicine Composition :  Norfloxacin
Prescription vs OTC : Prescription by Doctor required

About Nortee 400mg Tablet

Nortee 400mg Tablet is a used to treat uncomplicated urinary tract infections and cystitis caused by susceptible gram-negative and gram-positive bacteria. It is also prescribed to treat sexually transmitted disease (eg, uncomplicated urethral and cervical gonorrhoea) caused by N. gonorrhoeae.

This medicine is also used to treat prostatitis due to E. coli; ophthalmic solution for conjunctivitis. Nortee 400mg Tablet is not recommended in children <18 years of age. CNS stimulation may occur which may lead to tremor, restlessness, confusion, and very rarely to hallucinations or convulsive seizures.

However, remember that this drug will not be effective for infections that aren’t caused by bacteria (viral infections such as common cold and the flu). Using an antibiotic repetitively and for infections that aren’t bacterial will lead the medicine to lose its potency over a period of time.

The treatment plan and dosage will depend upon the severity of the condition. It is advised to take this drug minimum two hours prior to consuming other minerals/vitamins or such products containing aluminium/magnesium such as antacids.

For best results, take this medicine at regular intervals every day. Try to limit your intake of caffeinated beverages such as coffee or tea, for that matter, as caffeine can interfere with the medicine’s potency in all probability. Don’t consume any dairy product either two hours prior to or an hour after taking this medication.

Risk factors for this medicine include kidney disorders, heart afflictions and epileptic seizures. It isn’t recommended for children below the age of 12 years. Overdosing on this medicine can result in irregular (slow) heartbeats.

Few side effects include an allergic response in the form of rashes, irritation of the skin, itching, etc. (though very rare), chest pain, dizziness, confusion, seizures, liver damage, joint or muscle pain, a ringing sensation in the ears (tinnitus), lightheadedness, diarrhea, fatigue, nausea, headaches and troubled sleeping.

Don’t take narcotic pain medicines if you experience any of these side effects since these can cause you more harm than good. Yeast infection and oral thrush are other concerns that might show up if you use this medicine indiscriminately. Know from your doctor the names of all those drugs that could diminish the efficacy of this medication.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the uses of Nortee 400mg Tablet

    • Bacterial Infections

    • Cystitis

    • Prostatitis

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the contraindications of Nortee 400mg Tablet ?

    • Allergy

      Avoid taking Nortee 400mg Tablet if you have a known allergy to this medicine or any other medicines belonging to the class fluoroquinolones.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the side effects of Nortee 400mg Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Key highlights of Nortee 400mg Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 9 to 12 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed in 1 to 2 hours.

    • Are there any pregnancy warnings?

      This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      Use of this medicine is not recommended in women who breastfeed due to the adverse effect on the development of the infant's joints. Use only if clearly needed under the supervision of the doctor. Monitoring of undesired effects like diarrhea, diaper rash is necessary.

    • Is It safe with alcohol?

      It is unsafe to consume alcohol along with this medicine.

    • Is it safe to drive while on this medicine?

      It is not known whether Nortee 400mg Tablet affects the patients ability to drive or not.

    • Does this affect kidney function?

      Caution must be taken in patients with kidney disease. Adjustment of dose is needed. Kindly consult your doctor before taking it.

    • Does this affect liver function?

      Limited information is available regarding the use of this medicine in patients with liver disease. Kindly consult your doctor before doing it.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the substitutes for Nortee 400mg Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Nortee 400mg Tablet , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Where is the Nortee 400mg Tablet approved?

    • India

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    How does this medication work?

    This medicine works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

      What are the interactions of Nortee 400mg Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Information not available.
      • Interaction with Medicine

        Disulfiram

        Increased toxicity/serum levels: Quinolones cause increased levels or toxicity of digoxin, caffeine, warfarin, cyclosporine, and possibly theophylline. Cimetidine and probenecid increase quinolone levels.
      • Interaction with Disease

        Central Nervous System Depression

        If you suffer from CNS disorder and you take Nortee 400mg Tablet, then you may experience tremors, restlessness, anxiety, confusion and hallucinations. Avoid consuming caffeine-containing products like coffee, chocolates and energy drinks.

        Qt Prolongation

        Avoid using Nortee 400mg Tablet if you experience any chest discomfort. Regular cardiac function tests are to be performed if you have any heart disease (arrhythmia) or family history of heart disease.

        Colitis

        Avoid taking Nortee 400mg Tablet if you experience severe diarrhea, abdominal pain, and blood in stools after taking the medicine. Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.
      • Interaction with Food

        Dairy products

        The desired effect of Nortee 400mg Tablet is not observed if consumed with dairy products. There should be at least 2 hours gap between taking Nortee 400mg Tablet and dairy products.

        Decreases absorption with food; should be administered on an empty stomach with water

      FAQs about Nortee 400mg Tablet

      • Ques : What is Nortee 400mg Tablet?

        Ans : This medication belongs to the class of fluoroquinolones and used to treat Bacterial infections.

      • Ques : How long do I need to use Nortee 400mg Tablet before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Nortee 400mg Tablet?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Nortee 400mg Tablet empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Nortee 400mg Tablet?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      References

      • Ofloxacin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 31 May 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ofloxacin

      • Ofloxacin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 31 May 2022].Available from:

        https://go.drugbank.com/drugs/DB01165

      • OFLOXACIN Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 31 May 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=OFLOXACIN

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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