Octreotide acetate

Octreotide is a man-made (synthetic) version of a naturally occurring hormone known as somatostatin. It is an even more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Like somatostatin, it also suppresses LH response to GnRH, decreases splanchnic blood flow, and inhibits release of serotonin, gastrin, vasoactive intestinal peptide, secretin, motilin, and pancreatic polypeptide.

Single doses of octreotide acetate have been shown to inhibit gallbladder contractility and to decrease bile secretion in normal person.

It is used to treat severe diarrhea, flushing, and other symptoms that occur with certain cancers of the intestine.Octreotide also reduces the amount of growth hormone in the body, and so it is also used to treat acromegaly, a condition associated with overgrowth of the hands, feet, and parts of the face.

Common side effects/Adverse effects of Octreotide include:

• Nausea
• Vomiting
• loose/oily stools
• Diarrhea
• Constipation
• Stomach pain or upset
• Gas
• Bloating
• Dizziness
• Headache
• Signs of liver/gallbladder problems
• Signs of underactive thyroid
• Worsening heart conditions
• Numbness and tingling of legs/arms

Octreotide is administered by two routes - Intravenous or Subcutaneous. Dose ranges from 2,400 micrograms/day to 6,000 micrograms/day administered by continuous infusion (100 micrograms/hour to 250 micrograms/hour) or subcutaneously (1,500 micrograms t.i.d.).

Dosing of Sandostatin depends on the condition being treated and the response of the patient. Sandostatin may interact with bromocriptine, cyclosporine, diuretics (water pills), diabetes medication, or medicine for heart disease or high blood pressure. It may also restore the normal ability to become pregnant in females with acromegaly who have infertility.

Octreotide acetate alters the balance between the counter-regulatory hormones, insulin, glucagon and growth hormone, which may result in hypoglycemia or hyperglycemia. Octreotide acetate also suppresses secretion of thyroid stimulating hormone, which may result in hypothyroidism. Cardiac conduction abnormalities have also occurred during treatment with octreotide acetate.

Sandostatin (octreotide acetate) may be administered subcutaneously or intravenously. Subcutaneous injection is the usual route of administration of Sandostatin (octreotide acetate) for control of symptoms. Pain with subcutaneous administration may be reduced by using the smallest volume that will deliver the desired dose. Multiple subcutaneous injections at the same site within short periods of time should be avoided. Sites should be rotated in a systematic manner.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Acromegaly

• Carcinoid Tumours And Bleeding Esophageal Varices

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Diarrhoea

• Abdominal Pain

• Nausea

• Constipation

• Flatulence

• Headache

• Increased Glucose Level In Blood

• Gallstones

• Injection Site Reaction

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  Octreotide acetate is probably safe to use during pregnancy.
  Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.

• Are there any breast-feeding warnings?

  Octreotide acetate is probably safe to use during lactation. \nLimited human data suggests that the drug does not represent a significant risk to the baby.

• Is it safe to drive while on this medicine?

  Octreotide acetate does not usually affect your ability to drive.

• Does this affect kidney function?

  Octreotide acetate is safe to use in patients with kidney disease. No dose adjustment of Octreotide acetate is recommended.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Are there any missed dose instructions?

  If you miss a dose of Octreotide acetate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

Below is the list of medicines, which contains Octreotide acetate as ingredient

• Actide 0.1mg Injection

  Samarth Life Sciences Pvt Ltd

• Neoctide 0.1mg Injection

  Neon Laboratories Ltd

• Neoctide 0.05mg Injection

  Neon Laboratories Ltd

• Octate 0.1mg Injection

  Vhb Life Sciences Inc

• Octotide 0.1mg Injection

  Troikaa Pharmaceuticals Ltd

• Octotide 0.05mg Injection

  Troikaa Pharmaceuticals Ltd

• Okeron 0.1mg Injection

  Wockhardt Ltd

• Otide 0.05mg Injection

  United Biotech Pvt Ltd

• Varioct 0.05mg Injection

  Biocon

• Varitide 0.05mg Injection

  J B Chemicals and Pharmaceuticals Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

This medication is used to treat any tumours originating from excessive growth hormones in the body. The luteinizing hormone is also inhibited through the use of this drug. GnRH causes this action.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Medicine

  Forxiga 5Mg Tablet

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  Forxiga 10Mg Tablet

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